2,4,5-trimethylaniline;hydrochloride

2,4,5-trimethylaniline hydrochloride is an aromatic amine compound in its hydrochloride salt form, with the molecular formula C9H14ClN and CAS number 21436-97-5. This chemical substance has a molecular weight of 171.67 g/mol and belongs to the substituted aniline family, featuring three methyl groups attached to the benzene ring at positions 2, 4, and 5, combined with hydrochloric acid to form the stable salt form.

2,4,5-trimethylaniline hydrochloride is typically a crystalline solid at room temperature due to its salt form structure. As an aromatic amine hydrochloride, it generally exhibits good water solubility compared to its free base form, while maintaining limited solubility in non-polar organic solvents. The compound's physical appearance and specific properties like melting point and exact solubility values would depend on the specific grade and purity of the material.

2,4,5-trimethylaniline hydrochloride is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its aromatic amine structure makes it valuable for producing dyes, pigments, and various chemical compounds through substitution reactions. The compound serves as a building block in the synthesis of more complex molecules, particularly in research and development applications where substituted aniline derivatives are required for specific chemical transformations.

2,4,5-trimethylaniline hydrochloride requires careful handling due to its classification as Carcinogenic 1B and Acute Toxic 3. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection when handling powders. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact, and ensure proper hygiene practices including thorough hand washing after handling.

2,4,5-trimethylaniline hydrochloride should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly closed and properly labeled according to GHS requirements with appropriate danger pictograms (GHS06, GHS08, GHS09). Store separately from oxidizing agents, acids, and bases. Ensure storage areas have appropriate containment measures and access restrictions due to the substance's carcinogenic and toxic properties.

2,4,5-trimethylaniline hydrochloride exposure requires immediate action due to its acute toxicity. For skin contact, remove contaminated clothing and rinse thoroughly with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention immediately. Always consult emergency services for serious exposures.

2,4,5-trimethylaniline hydrochloride must be disposed of as hazardous waste through licensed waste management companies due to its carcinogenic and toxic properties. The substance cannot be disposed of through regular waste streams or sewage systems. Follow local and national regulations for hazardous chemical disposal, maintaining proper documentation and chain of custody. Consider waste minimization strategies and recovery options where technically feasible before disposal.

2,4,5-trimethylaniline hydrochloride is classified as ADR Class 6.1 (Toxic substances) Packing Group II, indicating significant transport hazards. Packages must comply with UN specifications and bear appropriate hazard labels and markings. Transport documents must include proper shipping names and emergency contact information. Only authorized carriers with appropriate training and equipment should handle transportation, following ADR regulations for toxic substances throughout the journey.

2,4,5-trimethylaniline hydrochloride is subject to comprehensive chemical regulations including REACH registration requirements and CLP classification obligations in Europe. Its Carcinogenic 1B classification imposes strict workplace exposure limits and handling requirements. The substance may face restrictions under various national and international chemical control frameworks. Companies must ensure compliance with occupational health regulations and maintain appropriate safety data sheets and exposure assessments.

2,4,5-trimethylaniline hydrochloride is available through OYSI, a specialized European distributor of technical chemicals and intermediates. OYSI provides reliable supply chains for research institutions, pharmaceutical companies, and industrial manufacturers requiring this compound. As a regulated substance with significant hazard classifications, purchase typically requires verification of legitimate end-use and compliance with applicable regulations. Contact OYSI directly for availability, specifications, and regulatory support.