2,4,5-trimethylaniline

C9H13N

CAS137-17-7

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Identification

CAS Number
137-17-7
EC Number
205-282-0
UN Number
2811
Index Number
612-197-00-6
PubChem CID
8717

Physical-chemical properties

Molecular Formula
C9H13N
Molar Mass
135.21 g/mol
IUPAC Name
2,4,5-trimethylaniline

Chemical Identifiers

InChI
InChI=1S/C9H13N/c1-6-4-8(3)9(10)5-7(6)2/h4-5H,10H2,1-3H3
InChI Key
BMIPMKQAAJKBKP-UHFFFAOYSA-N

Overview

2,4,5-trimethylaniline (CAS 137-17-7) is an aromatic amine compound with three methyl substituents on the benzene ring and primary amine functionality. This organic chemical compound belongs to the substituted aniline family, characterized by its distinctive molecular structure featuring a benzene ring substituted with methyl groups at positions 2, 4, and 5, along with an amino group. With a molecular formula of C9H13N and molecular weight of 135.21 g/mol, 2,4,5-trimethylaniline represents an important intermediate in organic synthesis and industrial chemistry applications. The compound exhibits typical aromatic amine properties, with the three methyl substituents significantly influencing its reactivity and physical characteristics compared to unsubstituted aniline. The electron-donating nature of the methyl groups enhances the nucleophilicity of the amino group while affecting the compound's solubility and volatility properties. Like other members of the aniline family, including 4-nitroaniline, it serves as a valuable building block for various chemical transformations. 2,4,5-trimethylaniline finds primary applications in the synthesis of dyes and pigments, where its substitution pattern provides specific color properties and stability characteristics. The compound is also utilized in pharmaceutical intermediate synthesis and as a precursor in the production of specialty chemicals for industrial applications. Its unique substitution pattern makes it particularly valuable for creating compounds with specific steric and electronic requirements. From a safety perspective, the compound is classified under ADR Class 6.1, indicating its toxic nature, requiring appropriate handling procedures and safety measures during storage and processing. Professional users should implement standard protocols for aromatic amine handling. OYSI provides 2,4,5-trimethylaniline to European industrial customers, ensuring reliable supply for specialized chemical synthesis applications.

Safety & Classification

No Hazard Classification

This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.

Transport (ADR)

UN Number2811
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name2,4,5-Trimethylanilin
Marine PollutantNo

Frequently Asked Questions

What is 2,4,5-trimethylaniline?

2,4,5-trimethylaniline is an aromatic amine compound with the molecular formula C9H13N and CAS number 137-17-7. This organic chemical belongs to the aniline family, characterized by an amino group (-NH2) attached to a benzene ring substituted with three methyl groups at positions 2, 4, and 5. With a molecular weight of 135.21 g/mol, it serves as an important intermediate in various chemical synthesis processes and industrial applications.

What are the physicochemical properties of 2,4,5-trimethylaniline?

2,4,5-trimethylaniline is typically a liquid or solid aromatic amine at room temperature, depending on purity and conditions. Like other substituted anilines, it generally exhibits limited water solubility but dissolves well in organic solvents such as alcohols, ethers, and aromatic hydrocarbons. The compound may have a characteristic amine-like odor and can be sensitive to light and air oxidation, potentially developing color upon exposure.

What is 2,4,5-trimethylaniline used for?

2,4,5-trimethylaniline is primarily used as an intermediate in organic synthesis and chemical manufacturing. It serves in the production of dyes, pigments, and pharmaceutical compounds where substituted aromatic amines are required. The compound is also utilized in the synthesis of specialty chemicals, agrochemicals, and as a building block for various industrial processes requiring specific aniline derivatives with controlled substitution patterns.

How to handle 2,4,5-trimethylaniline safely?

2,4,5-trimethylaniline should be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction to avoid inhalation exposure. Prevent skin and eye contact, as aromatic amines can be absorbed through the skin. Use proper laboratory techniques, avoid eating, drinking, or smoking in work areas, and wash hands thoroughly after handling.

How to store 2,4,5-trimethylaniline correctly?

2,4,5-trimethylaniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep away from oxidizing agents, acids, and incompatible materials. Store in original containers with proper labeling and maintain temperatures as recommended by the supplier. Ensure storage areas have appropriate spill containment measures and are accessible only to trained personnel.

What to do in case of contact with 2,4,5-trimethylaniline?

In case of skin contact with 2,4,5-trimethylaniline, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Remove from exposure and seek medical attention if symptoms develop. Do not induce vomiting if swallowed.

How to dispose of 2,4,5-trimethylaniline properly?

2,4,5-trimethylaniline must be disposed of according to local, national, and international waste regulations as a chemical waste. Contact licensed waste disposal companies specializing in organic chemical waste management. Do not discharge into drains, waterways, or soil. Small laboratory quantities may require special collection procedures, while larger industrial amounts need professional hazardous waste treatment. Always consult current waste disposal regulations in your jurisdiction.

How to transport 2,4,5-trimethylaniline?

2,4,5-trimethylaniline is classified under ADR Class 6.1 (Toxic substances), Packing Group II, indicating moderate toxicity for transportation purposes. It must be packaged in approved containers meeting UN specifications and properly labeled with hazard markings. Transport documentation must include proper shipping names and hazard information. Only use carriers licensed for dangerous goods transport and ensure compliance with all applicable transportation regulations.

Is 2,4,5-trimethylaniline subject to particular regulations?

2,4,5-trimethylaniline is subject to standard chemical regulations including REACH registration requirements in the European Union for commercial use. It falls under CLP regulation for classification and labeling, though currently shows no specific GHS classifications. The compound is not listed as an SVHC (Substance of Very High Concern). Users must comply with occupational safety regulations, environmental protection laws, and proper chemical management practices in their respective jurisdictions.

Where to buy 2,4,5-trimethylaniline in Europe?

2,4,5-trimethylaniline is available through OYSI, a European distributor of chemical products serving industrial and research customers across Europe. OYSI provides reliable supply chains for specialty chemicals including aromatic amines and intermediates. For procurement, contact OYSI directly to discuss specifications, quantities, packaging options, and delivery arrangements. Professional chemical distributors ensure proper handling, documentation, and regulatory compliance for chemical purchases.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.