4-(4-aminophenoxy)aniline

4-(4-aminophenoxy)aniline is an aromatic organic compound with the molecular formula C12H12N2O and CAS number 101-80-4. This chemical belongs to the family of aminophenyl compounds and features two aniline groups connected by an oxygen bridge. With a molecular weight of 200.24 g/mol, it is classified as a highly hazardous substance with carcinogenic, mutagenic, and reproductive toxicity properties, requiring strict handling protocols in industrial applications.

4-(4-aminophenoxy)aniline typically appears as a solid crystalline material at room temperature due to its aromatic structure and hydrogen bonding capabilities. The compound contains amino groups that can participate in hydrogen bonding, affecting its solubility properties. As an aromatic amine, it may exhibit limited water solubility but better solubility in organic solvents. The presence of both amino and ether functional groups influences its chemical reactivity and physical characteristics.

4-(4-aminophenoxy)aniline is primarily used as an intermediate in the synthesis of dyes, pigments, and polymers in the chemical industry. It serves as a building block for producing various aromatic compounds and can be utilized in the manufacture of specialty chemicals. Due to its amino functional groups, it may also be employed in the production of pharmaceutical intermediates and advanced materials. However, its use is strictly regulated due to its hazardous classification.

4-(4-aminophenoxy)aniline requires extreme caution during handling due to its carcinogenic and mutagenic properties. Essential personal protective equipment includes chemical-resistant gloves, protective clothing, eye protection, and respiratory protection when necessary. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. All handling procedures must follow strict safety protocols, and workers should be trained on the specific hazards associated with this substance before use.

4-(4-aminophenoxy)aniline should be stored in a cool, dry, well-ventilated area away from sources of ignition and incompatible materials. The storage area must be secure and accessible only to trained personnel due to the substance's hazardous classification. Containers should be kept tightly closed and properly labeled according to GHS requirements. Storage facilities should comply with local regulations for handling carcinogenic substances and include appropriate containment measures to prevent environmental release.

Immediate action is required in case of contact with 4-(4-aminophenoxy)aniline due to its acute toxicity. For skin contact, remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes. If inhaled, move the person to fresh air immediately. Seek medical attention promptly in all cases of exposure and provide the safety data sheet to medical personnel.

4-(4-aminophenoxy)aniline must be disposed of as hazardous waste according to local and national environmental regulations. Due to its carcinogenic and mutagenic properties, it cannot be disposed of through normal waste streams. Disposal should only be conducted by licensed hazardous waste management companies with appropriate permits. The waste classification includes considerations for its aquatic chronic toxicity, requiring special handling to prevent environmental contamination during the disposal process.

4-(4-aminophenoxy)aniline is classified under ADR Class 6.1 (toxic substances) Packing Group III for transportation purposes. All shipments must comply with dangerous goods regulations including proper packaging, labeling with GHS pictograms (GHS06, GHS08, GHS09), and documentation requirements. Vehicles must carry appropriate emergency equipment and drivers require dangerous goods training. The transport documentation must include the proper shipping name, UN number, and emergency contact information for incident response.

4-(4-aminophenoxy)aniline is subject to extensive regulatory oversight under REACH and CLP regulations in Europe due to its hazardous classification. The substance requires registration for import or manufacture above one tonne per year. Its carcinogenic and mutagenic properties (Carc. 1B; Muta. 1B) make it subject to authorization procedures and potential restrictions. Companies must maintain detailed safety data sheets, conduct risk assessments, and implement appropriate risk management measures throughout the supply chain.

4-(4-aminophenoxy)aniline is available through specialized chemical distributors in Europe, including OYSI, which serves as a reliable supplier of technical chemicals across European markets. Due to the substance's hazardous classification, purchases are restricted to qualified industrial users with appropriate safety measures and regulatory compliance. Buyers must demonstrate proper handling capabilities, storage facilities, and waste management procedures. Contact OYSI's technical team for availability, specifications, and regulatory guidance for your specific application requirements.