1,2-dimethylhydrazine

C2H8N2

CAS540-73-8
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
540-73-8
UN Number
2382
Index Number
007-013-00-0
PubChem CID
1322

Physical-chemical properties

Molecular Formula
C2H8N2
Molar Mass
60.10 g/mol
IUPAC Name
1,2-dimethylhydrazine

Chemical Identifiers

InChI
InChI=1S/C2H8N2/c1-3-4-2/h3-4H,1-2H3
InChI Key
DIIIISSCIXVANO-UHFFFAOYSA-N

Overview

1,2-dimethylhydrazine (CAS 540-73-8) is an organic hydrazine derivative with high toxicity and carcinogenic properties used in specialized chemical applications. This highly hazardous chemical compound belongs to the hydrazine family and presents significant safety challenges in industrial handling. With its molecular formula C2H8N2 and molecular weight of 60.1 g/mol, 1,2-dimethylhydrazine exhibits properties that make it both valuable for specific applications and extremely dangerous without proper safety protocols. The substance is classified as a Category 1B carcinogen under the CLP regulation, indicating sufficient evidence of carcinogenic potential in animal studies. Additionally, it carries Acute Toxicity Category 3 classifications across multiple exposure routes, demonstrating its severe health hazards. The compound also poses environmental risks with its Aquatic Chronic 2 classification, requiring careful environmental protection measures during handling and disposal. Due to its ADR Class 6.1 classification, 1,2-dimethylhydrazine requires specialized transport conditions as a toxic substance. The presence of GHS pictograms including health hazard (GHS08), skull and crossbones (GHS06), and environmental hazard (GHS09) symbols emphasizes the comprehensive risk profile of this material. In industrial applications, 1,2-dimethylhydrazine finds use primarily as a rocket fuel component and propellant in aerospace applications, as a chemical intermediate in pharmaceutical synthesis, and in specialized research applications. Unlike related compounds such as phenylhydrazine which has broader synthetic applications, 1,2-dimethylhydrazine's use is largely restricted due to its extreme toxicity profile. OYSI provides 1,2-dimethylhydrazine to qualified industrial customers with appropriate safety certifications and handling capabilities, ensuring full regulatory compliance and safe supply chain management.

Safety & Classification

Danger
Classification:

Carc. 1B; Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2382
ADR Class6.1
Packing GroupI
Tunnel CodeC/D
Proper Shipping NameDimethylhydrazin, symmetrisch
Marine PollutantNo

Frequently Asked Questions

What is 1,2-dimethylhydrazine?

1,2-dimethylhydrazine is an organic chemical compound with the molecular formula C2H8N2 and CAS number 540-73-8. This hydrazine derivative has a molecular weight of 60.1 g/mol and is classified as a highly hazardous substance due to its carcinogenic properties (Category 1B) and acute toxicity. It poses significant health risks and requires specialized handling procedures in industrial applications.

What are the physicochemical properties of 1,2-dimethylhydrazine?

1,2-dimethylhydrazine is a colorless to pale yellow liquid at room temperature with a characteristic amine-like odor. It is highly soluble in water and polar organic solvents due to its hydrazine structure. The compound is hygroscopic and can absorb moisture from air. It has a relatively low molecular weight of 60.1 g/mol and exhibits basic properties typical of substituted hydrazines.

What is 1,2-dimethylhydrazine used for?

1,2-dimethylhydrazine is primarily used as a rocket propellant component, particularly as a hypergolic fuel in aerospace applications. It serves as an intermediate in the synthesis of pharmaceuticals and specialty chemicals. The compound is also utilized in research applications for chemical synthesis and as a reagent in analytical chemistry, though its use is strictly regulated due to its carcinogenic properties.

How to handle 1,2-dimethylhydrazine safely?

1,2-dimethylhydrazine requires extreme caution during handling due to its carcinogenic and acutely toxic nature. Essential personal protective equipment includes chemical-resistant gloves, full face protection, and respiratory protection with appropriate filters. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Emergency shower and eyewash facilities must be readily accessible.

How to store 1,2-dimethylhydrazine correctly?

1,2-dimethylhydrazine must be stored in tightly sealed containers in cool, dry, well-ventilated areas away from heat sources and incompatible materials. Store separately from oxidizing agents, acids, and combustible materials to prevent dangerous reactions. Use appropriate secondary containment and ensure storage areas are equipped with emergency response equipment. Temperature control is essential to prevent decomposition and vapor formation.

What to do in case of contact with 1,2-dimethylhydrazine?

Immediate action is required for any contact with 1,2-dimethylhydrazine. For skin contact, remove contaminated clothing and flush with copious amounts of water for at least 15 minutes. In case of eye contact, rinse immediately with water for 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting. Seek immediate medical attention in all cases and provide safety data sheet to medical personnel.

How to dispose of 1,2-dimethylhydrazine properly?

1,2-dimethylhydrazine disposal requires specialized hazardous waste treatment due to its carcinogenic classification. The substance must be disposed of through licensed hazardous waste contractors following local and European waste regulations. Incineration at high temperatures in approved facilities is typically required. Never dispose of through regular waste streams or sewers. Maintain proper documentation and waste tracking throughout the disposal process.

How to transport 1,2-dimethylhydrazine?

1,2-dimethylhydrazine is classified under ADR as Class 6.1 (toxic substances), Packing Group I, indicating the highest level of toxicity. Transport requires specialized packaging meeting UN specifications and proper hazard labeling with GHS06, GHS08, and GHS09 pictograms. Only authorized carriers with appropriate training and equipment should handle transportation. Shipping documentation must include proper shipping names and emergency response information.

Is 1,2-dimethylhydrazine subject to particular regulations?

1,2-dimethylhydrazine is subject to strict European regulations under REACH and CLP due to its carcinogenic classification (Category 1B) and acute toxicity. The substance requires specialized authorization for commercial use and is subject to workplace exposure limits. Additional restrictions may apply for certain applications. Companies must comply with notification requirements and implement appropriate risk management measures throughout the supply chain.

Where to buy 1,2-dimethylhydrazine in Europe?

1,2-dimethylhydrazine is available through specialized chemical distributors in Europe, including OYSI, which provides technical-grade chemicals to industrial customers. Due to its hazardous classification and regulatory requirements, purchases require proper documentation and compliance verification. OYSI offers expert technical support and ensures full regulatory compliance for European customers requiring this specialized chemical compound for legitimate industrial applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.