Benzene

C6H6

benzene

CAS71-43-2
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
71-43-2
EC Number
200-753-7
UN Number
1114
Index Number
601-020-00-8
PubChem CID
241

Physical-chemical properties

Molecular Formula
C6H6
Molar Mass
78.11 g/mol
IUPAC Name
benzene

Chemical Identifiers

InChI
InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H
InChI Key
UHOVQNZJYSORNB-UHFFFAOYSA-N

Overview

Benzene (CAS 71-43-2) is an aromatic hydrocarbon compound with a characteristic ring structure and high industrial significance as a petrochemical building block. As one of the most fundamental aromatic compounds in organic chemistry, benzene serves as a cornerstone for numerous industrial processes and chemical syntheses. This colorless, highly flammable liquid exhibits a distinctive sweet odor and demonstrates exceptional chemical stability due to its unique hexagonal ring structure with delocalized electrons. The compound's molecular formula C6H6 represents the simplest aromatic hydrocarbon, making it an essential starting material for producing more complex aromatic compounds including ethylbenzene and styrene. Benzene presents significant safety considerations due to its classification as a Category 1A carcinogen and Category 1B mutagen. The substance requires careful handling protocols, appropriate ventilation systems, and specialized storage conditions to minimize exposure risks. Its flammable nature, combined with potential health hazards including skin and eye irritation, necessitates comprehensive safety measures including proper personal protective equipment and emergency response procedures. The compound's low flash point and high volatility demand particular attention to ignition sources and vapor control measures. Primary industrial applications include its use as a feedstock for producing cyclohexane, cumene, and various aromatic derivatives essential in plastics manufacturing, synthetic rubber production, and pharmaceutical intermediates. The petrochemical industry extensively utilizes benzene for synthesizing styrene monomer, phenol, and aniline, which serve as precursors for countless consumer and industrial products. Additionally, benzene functions as a solvent in specialized chemical processes, though this application has decreased due to health and environmental concerns. OYSI provides high-quality benzene with comprehensive technical documentation and regulatory compliance support for European industrial customers.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Carc. 1A; Muta. 1B; Asp. Tox. 1; STOT RE 1; Skin Irrit. 2; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H350

May cause cancer.

H340

May cause genetic defects.

H304

May be fatal if swallowed and enters airways.

H372

Causes damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1114
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameBenzen
Marine PollutantNo

Frequently Asked Questions

What is benzene?

Benzene is an aromatic hydrocarbon with the molecular formula C6H6 and a molar mass of 78.11 g/mol. It consists of a ring of six carbon atoms with alternating double bonds, making it one of the most fundamental compounds in organic chemistry. Benzene is classified as a highly hazardous substance due to its carcinogenic, mutagenic, and flammable properties, requiring strict safety measures during handling and use.

What are the physicochemical properties of benzene?

Benzene is a colorless liquid at room temperature with a characteristic sweet aromatic odor. It has a boiling point of 80.1°C and a melting point of 5.5°C. Benzene is highly volatile and immiscible with water but readily dissolves in organic solvents. It has a density of 0.8765 g/cm³ and forms highly flammable vapor-air mixtures with explosive limits between 1.2-7.8% by volume.

What is benzene used for?

Benzene is primarily used as a raw material in the chemical industry for producing other chemicals. Its main applications include the manufacture of styrene for plastics, phenol for resins, cyclohexane for nylon production, and various detergents and pesticides. Due to its carcinogenic properties, benzene's direct use has been heavily restricted, and it is mainly utilized in closed industrial processes with strict exposure controls.

How to handle benzene safely?

Benzene handling requires strict safety protocols due to its carcinogenic and flammable nature. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and respiratory protection in enclosed spaces. Work areas must be well-ventilated with explosion-proof equipment. Avoid all ignition sources and ensure emergency shower and eyewash stations are readily available. Only trained personnel should handle benzene in controlled industrial environments.

How to store benzene correctly?

Benzene must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use only approved containers made of compatible materials such as steel or aluminum. Storage areas should be equipped with fire suppression systems and spill containment measures. Keep benzene separated from oxidizing agents and incompatible materials. Ensure proper grounding of containers to prevent static electricity buildup.

What to do in case of contact with benzene?

Benzene exposure requires immediate action depending on the route of contact. For skin contact, immediately remove contaminated clothing and wash the affected area with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for 15 minutes. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention in all cases.

How to dispose of benzene appropriately?

Benzene disposal must comply with local and international hazardous waste regulations. It cannot be disposed of in regular waste streams due to its carcinogenic and environmental hazard classification. Benzene waste should be collected in appropriate containers, labeled correctly, and handed over to licensed hazardous waste disposal companies. Incineration at high temperatures in specialized facilities is typically the preferred disposal method.

How to transport benzene?

Benzene is classified as ADR Class 3 (flammable liquids), Packing Group II, requiring specialized transport procedures. It must be shipped in UN-approved packaging with proper labeling including GHS pictograms (GHS02, GHS08, GHS07) and hazard markings. Transportation vehicles must comply with ADR regulations for flammable substances, including appropriate placarding, emergency equipment, and driver certification for dangerous goods transport.

Is benzene subject to specific regulations?

Benzene is heavily regulated under multiple frameworks including REACH, CLP, and national chemical safety laws. It is classified as Carcinogenic 1A and Mutagenic 1B under CLP regulation, requiring strict labeling with 'Danger' signal words. Many jurisdictions have established extremely low occupational exposure limits and restrict its use in consumer products. Industrial users must implement rigorous risk management measures and report usage under REACH requirements.

Where to buy benzene in Europe?

Benzene is available through specialized chemical distributors in Europe, including OYSI, which supplies industrial-grade benzene to qualified customers across European markets. Due to its hazardous classification, benzene sales are restricted to industrial users with proper handling capabilities and regulatory compliance. Buyers must typically provide documentation of intended use, safety measures, and relevant permits before purchase approval.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.