N-methylaniline

N-methylaniline is an organic aromatic amine compound with the chemical formula C7H9N and CAS number 100-61-8. This substance consists of an aniline molecule where one hydrogen atom on the amino group is replaced by a methyl group. With a molecular weight of 107.15 g/mol, N-methylaniline is classified as a hazardous chemical requiring careful handling due to its acute toxicity and potential for repeated dose toxicity.

N-methylaniline is typically a colorless to pale yellow liquid at room temperature with a characteristic aniline-like odor. As an aromatic amine, it exhibits moderate polarity and is partially soluble in water while being miscible with most organic solvents such as alcohol and ether. The compound is sensitive to light and air, which can cause discoloration over time, and it has a tendency to darken upon exposure to oxidizing conditions.

N-methylaniline is primarily used as an intermediate in the synthesis of dyes, pharmaceuticals, and agrochemicals. It serves as a key building block in the production of various organic compounds, particularly in the manufacture of azo dyes and pigments. The compound is also utilized in the synthesis of certain pharmaceutical active ingredients and as a chemical intermediate in specialty chemical manufacturing processes within industrial applications.

N-methylaniline requires strict safety measures due to its Acute Tox. 3 classification and STOT RE 2 hazard class. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Avoid skin contact, inhalation, and ingestion as the substance can cause serious health effects. Work in fume hoods when possible and ensure emergency eyewash and shower facilities are readily accessible in the work area.

N-methylaniline must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep away from oxidizing agents, acids, and incompatible materials to prevent dangerous reactions. Storage areas should be equipped with appropriate containment measures for spill control. Due to its aquatic toxicity classification, special precautions must be taken to prevent environmental release during storage.

Immediate action is critical due to N-methylaniline's acute toxicity. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical attention. For eye contact, flush with water for at least 15 minutes and remove contact lenses if present. In all cases of exposure, seek immediate medical attention and provide the safety data sheet to medical personnel.

N-methylaniline disposal must comply with local and international hazardous waste regulations due to its toxic and environmentally hazardous properties. The substance cannot be disposed of in regular waste streams or sewage systems due to its aquatic toxicity classification. Disposal should only be conducted by licensed hazardous waste disposal companies through appropriate treatment methods such as incineration at authorized facilities with proper emission controls.

N-methylaniline is classified under ADR regulations as Class 6.1 (Toxic substances), Packing Group III. Transport requires appropriate UN-approved packaging and proper hazard labeling including GHS06, GHS08, and GHS09 pictograms. Shipping documents must include the correct shipping name and hazard declarations. Carriers must be trained in hazardous materials handling and emergency response procedures for toxic substances during transportation.

N-methylaniline is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The substance carries multiple hazard classifications requiring specific labeling with 'Danger' signal word and appropriate pictograms. While not currently listed as an SVHC substance, it remains under regulatory scrutiny due to its toxic properties and environmental impact, requiring compliance with occupational exposure limits and environmental protection measures.

N-methylaniline is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. As an established chemical supplier, OYSI provides N-methylaniline with complete regulatory documentation, safety data sheets, and technical support. Professional buyers can contact OYSI directly for product availability, specifications, and delivery arrangements to European locations while ensuring full regulatory compliance for this controlled substance.