Aniline
C6H7N
aniline
Consulting for Aniline
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Identification
- CAS Number
- 62-53-3
- EC Number
- 200-539-3
- UN Number
- 1547
- Index Number
- 612-008-00-7
- PubChem CID
- 6115
Physical-chemical properties
- Molecular Formula
- C6H7N
- Molar Mass
- 93.13 g/mol
- IUPAC Name
- aniline
Chemical Identifiers
- InChI
- InChI=1S/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2
- InChI Key
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N
Overview
Aniline (CAS 62-53-3) is a primary aromatic amine with high industrial significance and notable toxicological concerns requiring careful handling protocols. This colorless to pale yellow organic compound serves as a fundamental building block in the chemical industry, particularly for manufacturing dyes, pharmaceuticals, and polymers. With the molecular formula C6H7N and a molar mass of 93.13 g/mol, aniline consists of a benzene ring directly attached to an amino group, making it the simplest aromatic amine. The substance exhibits basic properties due to its amino functionality while maintaining the characteristic stability of aromatic compounds. Safety considerations are paramount when handling aniline, as it carries multiple hazard classifications including carcinogenicity (Category 2), mutagenicity (Category 2), and acute toxicity through various exposure routes. The compound can cause severe eye damage, skin sensitization, and specific target organ toxicity with repeated exposure. These properties necessitate strict adherence to safety protocols, including appropriate personal protective equipment and controlled handling environments. The substance falls under ADR transport class 6.1, reflecting its toxic nature during transportation. Primary industrial applications include the production of methylene diphenyl diisocyanate (MDI) for polyurethane manufacturing, synthesis of rubber processing chemicals, and pharmaceutical intermediates. The compound also serves in manufacturing antioxidants and dye intermediates. Related compounds such as aniline hydrochloride share similar applications but offer different solubility and handling characteristics for specific industrial processes. OYSI maintains reliable supply chains for aniline and related aromatic amines, supporting European industries with consistent quality and comprehensive technical documentation for safe industrial use.
Safety & Classification
Carc. 2; Muta. 2; Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE 1; Eye Dam. 1; Skin Sen...
GHS Pictograms
Health Hazard
GHS08
Serious health hazard. May cause cancer, organ damage, or genetic defects.
Skull and Crossbones
GHS06
Acute toxicity. Fatal if swallowed, in contact with skin, or if inhaled.
Corrosion
GHS05
Corrosive. Causes severe skin burns and eye damage.
Environment
GHS09
Environmental hazard. Toxic to aquatic life with long lasting effects.
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Suspected of causing cancer.
Suspected of causing genetic defects.
Toxic if inhaled.
Toxic in contact with skin.
Toxic if swallowed.
Causes damage to organs through prolonged or repeated exposure.
Causes serious eye damage.
May cause an allergic skin reaction.
Very toxic to aquatic life.
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1547 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | Anilin |
| Marine Pollutant | No |
Frequently Asked Questions
What is aniline?
Aniline is an aromatic amine with the chemical formula C6H7N and CAS number 62-53-3. It consists of a benzene ring attached to an amino group (-NH2), making it the simplest aromatic amine. With a molecular weight of 93.13 g/mol, aniline is a fundamental building block in organic chemistry and serves as a precursor for numerous industrial chemicals and dyes.
What are the physicochemical properties of aniline?
Aniline is a colorless to pale yellow oily liquid at room temperature with a characteristic fishy or musty odor. It has a boiling point of 184°C and is slightly soluble in water but readily dissolves in organic solvents like ethanol and ether. The compound darkens upon exposure to air and light due to oxidation, and its aromatic amine structure makes it basic in nature.
What is aniline used for?
Aniline is primarily used as an intermediate in the production of polyurethane foams, rubber chemicals, and dyes. It serves as a key raw material for manufacturing methylene diphenyl diisocyanate (MDI), antioxidants, and pharmaceutical intermediates. The chemical industry also utilizes aniline in producing herbicides, synthetic resins, and various aromatic compounds essential for industrial applications.
How to handle aniline safely?
Aniline requires careful handling due to its toxic nature and multiple hazard classifications including carcinogenicity and mutagenicity. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods, avoiding skin contact and inhalation. Emergency eyewash stations and safety showers must be readily accessible in work areas.
How to store aniline correctly?
Aniline should be stored in tightly sealed containers in cool, dry, well-ventilated areas away from heat sources, strong oxidizers, and acids. Storage areas must be equipped with appropriate spill containment and ventilation systems. The substance should be protected from light and air exposure to prevent degradation and discoloration. Secondary containment is recommended due to its toxic properties and environmental hazards.
What to do in case of contact with aniline?
Immediate medical attention is required for any exposure to aniline due to its high toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with water for at least 15 minutes. If inhaled, move to fresh air and seek medical care. For ingestion, do not induce vomiting and contact emergency services immediately.
How to dispose of aniline properly?
Aniline must be disposed of as hazardous waste through licensed waste disposal contractors in accordance with local and European regulations. The substance cannot be discharged into sewers or the environment due to its toxicity and environmental impact. Contaminated materials, including packaging and absorbents, require proper hazardous waste classification and disposal through authorized facilities following waste management protocols.
How to transport aniline?
Aniline is classified as ADR Class 6.1 (toxic substances) Packing Group II, requiring specialized dangerous goods packaging and documentation. Transportation must comply with ADR regulations including proper labeling with GHS pictograms (GHS08, GHS06, GHS05, GHS09) and the 'Danger' signal word. Only certified dangerous goods transporters with appropriate vehicle equipment and driver training can handle aniline shipments.
Is aniline subject to specific regulations?
Aniline is subject to strict European regulations under REACH and CLP due to its classification as carcinogenic (Category 2), mutagenic (Category 2), and toxic. While not currently listed as a Substance of Very High Concern (SVHC), it requires safety data sheets, hazard communication, and compliance with occupational exposure limits. Industrial users must implement risk management measures and report usage under REACH requirements.
Where to buy aniline in Europe?
OYSI serves as a reliable European distributor for aniline, providing quality chemical products to industrial customers across Europe. As a specialized chemical distributor, OYSI ensures proper packaging, documentation, and regulatory compliance for aniline shipments. Contact OYSI directly for availability, technical specifications, and delivery options tailored to your specific industrial requirements and location within Europe.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.