(2S)-2-hydroxypropanoic acid

C3H6O3

CAS79-33-4
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
79-33-4
EC Number
201-196-2
UN Number
3261
Index Number
607-743-00-5
PubChem CID
107689

Physical-chemical properties

Molecular Formula
C3H6O3
Molar Mass
90.08 g/mol
IUPAC Name
(2S)-2-hydroxypropanoic acid

Chemical Identifiers

InChI
InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1
InChI Key
JVTAAEKCZFNVCJ-REOHCLBHSA-N

Overview

(2S)-2-hydroxypropanoic acid (CAS 79-33-4) is an optically active alpha-hydroxy carboxylic acid with natural occurrence and significant industrial applications. This chiral organic compound, commonly known as L-lactic acid, represents the naturally occurring stereoisomer of lactic acid and plays a crucial role in various biological and industrial processes. With the molecular formula C3H6O3 and a molar mass of 90.08 g/mol, this substance exhibits the characteristic properties of both a carboxylic acid and a secondary alcohol due to its hydroxyl group positioned on the alpha carbon. The compound presents specific safety considerations requiring careful handling protocols. Classified under GHS pictogram GHS05 with the signal word "Danger," it demonstrates corrosive properties toward skin (Skin Corr. 1C) and can cause serious eye damage (Eye Dam. 1). These characteristics necessitate appropriate personal protective equipment and storage conditions. For transportation purposes, it falls under ADR class 8, indicating its corrosive nature during shipping and handling operations. Industrial applications of (2S)-2-hydroxypropanoic acid span multiple sectors, including food and beverage production where it serves as a natural preservative and pH regulator, pharmaceutical manufacturing for drug synthesis and formulation, and polymer industry for biodegradable plastic production. Unlike more aggressive chemical compounds such as trichlorostibane or pentachloro-lambda5-phosphane, this organic acid offers safer handling characteristics while maintaining effective functionality in various applications. The compound's biocompatible nature and renewable sourcing make it increasingly valuable in sustainable chemistry applications, particularly in the development of environmentally friendly materials and processes. OYSI provides reliable access to (2S)-2-hydroxypropanoic acid for European industrial customers requiring consistent quality and technical support.

Safety & Classification

Danger
Classification:

Skin Corr. 1C; Eye Dam. 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H314

Causes severe skin burns and eye damage.

H318

Causes serious eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3261
ADR Class8
Packing GroupIII
Tunnel CodeE
Proper Shipping NameL-(+)-Milchsäure
Marine PollutantNo

Frequently Asked Questions

What is (2S)-2-hydroxypropanoic acid?

(2S)-2-hydroxypropanoic acid is the S-enantiomer of lactic acid, a naturally occurring organic acid with the molecular formula C3H6O3. This chiral carboxylic acid features a hydroxyl group on the second carbon atom, giving it both acidic and alcohol properties. With a molecular weight of 90.08 g/mol and CAS number 79-33-4, it is classified as a corrosive substance requiring careful handling due to its potential to cause skin and eye damage.

What are the physicochemical properties of (2S)-2-hydroxypropanoic acid?

(2S)-2-hydroxypropanoic acid is typically a colorless to slightly yellow liquid or crystalline solid at room temperature, depending on concentration. It is highly soluble in water and polar solvents due to its hydroxyl and carboxyl functional groups. The substance has a slightly sour odor characteristic of organic acids and exhibits hygroscopic properties, readily absorbing moisture from the atmosphere. Its corrosive nature stems from its acidic pH in aqueous solutions.

What is (2S)-2-hydroxypropanoic acid used for?

(2S)-2-hydroxypropanoic acid serves multiple industrial applications including food and beverage production as an acidulant and preservative, pharmaceutical manufacturing as an intermediate, and cosmetic formulations. It is widely used in the production of biodegradable polymers like polylactic acid (PLA), leather tanning processes, and as a pH regulator in various chemical processes. The compound also finds application in textile treatment and metal cleaning operations due to its chelating properties.

How to handle (2S)-2-hydroxypropanoic acid safely?

Safe handling of (2S)-2-hydroxypropanoic acid requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Skin Corr. 1C and Eye Dam. 1 classifications. Work in well-ventilated areas or under fume hoods to avoid inhalation. Use corrosion-resistant tools and containers, avoid contact with skin and eyes, and ensure emergency eyewash stations and safety showers are readily accessible. Always follow GHS05 pictogram warnings indicating corrosive hazards.

How to store (2S)-2-hydroxypropanoic acid correctly?

(2S)-2-hydroxypropanoic acid should be stored in tightly sealed, corrosion-resistant containers made of suitable materials like high-density polyethylene or glass. Keep in a cool, dry, well-ventilated area away from incompatible substances such as strong bases, oxidizing agents, and metals. Maintain storage temperatures as specified by the manufacturer and protect from direct sunlight. Ensure proper labeling with hazard information and implement appropriate containment measures to prevent environmental release.

What to do in case of contact with (2S)-2-hydroxypropanoic acid?

Immediate action is required upon contact with (2S)-2-hydroxypropanoic acid due to its corrosive nature. For skin contact, immediately flush with copious amounts of water for at least 15 minutes while removing contaminated clothing. For eye contact, rinse immediately with water for at least 15 minutes and seek immediate medical attention. If inhaled, move to fresh air and seek medical help if breathing difficulties occur. Always consult a physician and provide the safety data sheet for proper medical treatment.

How to dispose of (2S)-2-hydroxypropanoic acid appropriately?

(2S)-2-hydroxypropanoic acid disposal must comply with local, national, and EU waste regulations as it is classified as corrosive waste. Neutralization with appropriate alkaline substances under controlled conditions may be possible before disposal, but should only be performed by trained personnel. Contact licensed waste disposal companies for collection and treatment. Never dispose of down drains or into the environment. Maintain proper waste documentation and follow the waste hierarchy principles of the EU Waste Framework Directive.

How to transport (2S)-2-hydroxypropanoic acid?

(2S)-2-hydroxypropanoic acid is classified under ADR Class 8 (Corrosive substances), Packing Group III, indicating it requires special transport considerations. Use UN-approved packaging suitable for corrosive liquids, ensure proper labeling with hazard diamonds, and provide transport documentation including safety data sheets. Vehicles must be equipped with appropriate spill containment materials and drivers require ADR training. Follow ADR regulations for loading, segregation from incompatible substances, and emergency response procedures during transport.

Is (2S)-2-hydroxypropanoic acid subject to specific regulations?

(2S)-2-hydroxypropanoic acid is subject to European REACH regulation requiring registration for import/manufacture above one tonne per year. Under CLP regulation, it must be classified and labeled according to its hazard properties (Skin Corr. 1C, Eye Dam. 1). The substance is not currently listed as a Substance of Very High Concern (SVHC). Compliance with occupational exposure limits, waste regulations, and transport requirements (ADR) is mandatory. Always verify current regulatory status as requirements may change.

Where to buy (2S)-2-hydroxypropanoic acid in Europe?

(2S)-2-hydroxypropanoic acid is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. OYSI provides quality chemical products with proper documentation, safety data sheets, and regulatory compliance support. Professional customers can contact OYSI for availability, specifications, and pricing information. The company ensures proper packaging, labeling, and transport arrangements in accordance with European regulations, making it a reliable source for industrial chemical procurement needs.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.