(2S)-2-hydroxypropanoic acid

C3H6O3

CAS79-33-4
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
79-33-4
EC Number
201-196-2
UN Number
3261
Index Number
607-743-00-5
PubChem CID
107689

Physical-chemical properties

Molecular Formula
C3H6O3
Molar Mass
90.08 g/mol
IUPAC Name
(2S)-2-hydroxypropanoic acid

Chemical Identifiers

InChI
InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1
InChI Key
JVTAAEKCZFNVCJ-REOHCLBHSA-N

Overview

(2S)-2-hydroxypropanoic acid (CAS 79-33-4) is a chiral alpha-hydroxy carboxylic acid with antimicrobial and keratolytic properties widely used in industrial applications. This optically active compound, also known as L-lactic acid, represents the naturally occurring enantiomer of lactic acid and plays a crucial role in various industrial processes. With the molecular formula C3H6O3 and a molecular weight of 90.08 g/mol, this substance exhibits significant commercial importance due to its biodegradable nature and versatile chemical properties. The (S)-configuration provides specific stereochemical characteristics that distinguish it from its racemic mixture, making it particularly valuable in applications requiring optical purity. From a safety perspective, (2S)-2-hydroxypropanoic acid is classified as a corrosive substance under the GHS classification system, carrying the danger signal word and requiring careful handling protocols. The compound falls under skin corrosion category 1C and eye damage category 1, necessitating appropriate personal protective equipment during handling and storage. Its classification under ADR class 8 indicates its corrosive nature for transportation purposes, requiring compliance with specific packaging and labeling requirements. Industrial applications include its use as a pH regulator and chemical intermediate in pharmaceutical manufacturing, food processing auxiliaries, and biodegradable polymer production. Unlike more aggressive chemicals such as trichlorostibane or pentachloro-lambda5-phosphane, this alpha-hydroxy acid offers a more environmentally compatible option for many industrial processes. The compound also serves as a building block for specialty chemical synthesis and as a processing aid in textile and leather industries. OYSI maintains reliable supply chains for (2S)-2-hydroxypropanoic acid to support diverse European industrial requirements with consistent quality specifications.

Safety & Classification

Danger
Classification:

Skin Corr. 1C; Eye Dam. 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H314

Causes severe skin burns and eye damage.

H318

Causes serious eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3261
ADR Class8
Packing GroupIII
Tunnel CodeE
Proper Shipping NameL-(+)-Milchsäure
Marine PollutantNo

Frequently Asked Questions

What is (2S)-2-hydroxypropanoic acid?

(2S)-2-hydroxypropanoic acid is the S-enantiomer of lactic acid, a naturally occurring organic acid with the molecular formula C3H6O3. This chiral compound has a molecular weight of 90.08 g/mol and is classified as a corrosive substance under GHS regulations. It is characterized by the presence of both a carboxyl group and a hydroxyl group, making it an alpha-hydroxy acid with significant industrial and biological importance.

What are the physico-chemical properties of (2S)-2-hydroxypropanoic acid?

(2S)-2-hydroxypropanoic acid is typically a colorless to slightly yellow liquid or crystalline solid at room temperature. It is highly soluble in water and polar solvents due to its hydroxyl and carboxyl functional groups. The compound has a slightly sour odor characteristic of organic acids. Its corrosive nature (Skin Corr. 1C; Eye Dam. 1) indicates it can cause severe chemical burns upon contact with skin and eyes.

What is (2S)-2-hydroxypropanoic acid used for?

(2S)-2-hydroxypropanoic acid is widely used in the food industry as an acidulant, preservative, and flavoring agent. It serves as a key intermediate in pharmaceutical manufacturing and is utilized in the production of biodegradable polymers like polylactic acid (PLA). The compound also finds applications in cosmetics as an exfoliating agent, in leather tanning processes, and as a pH regulator in various industrial formulations.

How to handle (2S)-2-hydroxypropanoic acid safely?

(2S)-2-hydroxypropanoic acid requires careful handling due to its corrosive properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume extraction systems. Emergency eyewash stations and safety showers must be readily accessible. Avoid generating aerosols and ensure proper training on corrosive substance handling procedures before use.

How to store (2S)-2-hydroxypropanoic acid correctly?

(2S)-2-hydroxypropanoic acid should be stored in tightly sealed, corrosion-resistant containers made of suitable materials like high-density polyethylene or glass. Storage areas must be cool, dry, and well-ventilated, away from incompatible materials such as strong bases, oxidizing agents, and metals. Containers should be clearly labeled and stored in secondary containment to prevent spills. Regular inspection of storage containers is essential to detect any signs of corrosion or leakage.

What to do in case of contact with (2S)-2-hydroxypropanoic acid?

Immediate action is required upon contact with (2S)-2-hydroxypropanoic acid. For skin contact, remove contaminated clothing and flush the affected area with copious amounts of water for at least 15 minutes. In case of eye contact, rinse immediately with water for at least 15 minutes while holding eyelids open. If inhaled, move the person to fresh air. Seek immediate medical attention in all cases of exposure, as this substance can cause severe chemical burns.

How to dispose of (2S)-2-hydroxypropanoic acid appropriately?

(2S)-2-hydroxypropanoic acid waste must be disposed of according to local and national hazardous waste regulations. The substance cannot be disposed of in regular drains or waste streams due to its corrosive classification. Waste should be collected in appropriate containers and handed over to licensed waste disposal companies. Neutralization may be possible under controlled conditions by qualified personnel, but professional waste management services are recommended for safe and compliant disposal.

How to transport (2S)-2-hydroxypropanoic acid?

(2S)-2-hydroxypropanoic acid is classified as ADR Class 8 (corrosive substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation for shipment. Packages must bear appropriate hazard labels and be constructed to withstand the corrosive nature of the contents. Transport vehicles must comply with ADR regulations, and drivers require proper training and certification for carrying corrosive materials.

Is (2S)-2-hydroxypropanoic acid subject to specific regulations?

(2S)-2-hydroxypropanoic acid is regulated under the CLP Regulation in Europe, requiring appropriate classification, labeling, and safety data sheets. While it is not currently listed as a Substance of Very High Concern (SVHC) under REACH, suppliers must comply with registration requirements if importing or manufacturing above specified tonnage thresholds. Food-grade applications are subject to additional food safety regulations, and pharmaceutical uses require compliance with relevant medicinal product legislation.

Where to buy (2S)-2-hydroxypropanoic acid in Europe?

(2S)-2-hydroxypropanoic acid is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides reliable supply chains across Europe with proper regulatory compliance and technical support. As a professional chemical distributor, OYSI ensures appropriate packaging, documentation, and safety data sheets for industrial customers. Contact OYSI directly for availability, specifications, and technical assistance regarding (2S)-2-hydroxypropanoic acid procurement for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.