2-(dimethylamino)ethanol

C4H11NO

CAS108-01-0
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

Consulting for 2-(dimethylamino)ethanol

Our experts support you with application, dosage, and compliance.

Request Consultation

Identification

CAS Number
108-01-0
EC Number
203-542-8
UN Number
2051
Index Number
603-047-00-0
PubChem CID
7902

Physical-chemical properties

Molecular Formula
C4H11NO
Molar Mass
89.14 g/mol
IUPAC Name
2-(dimethylamino)ethanol

Chemical Identifiers

InChI
InChI=1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3
InChI Key
UEEJHVSXFDXPFK-UHFFFAOYSA-N

Overview

2-(dimethylamino)ethanol (CAS 108-01-0) is an organic amine compound with both tertiary amine and primary alcohol functional groups, exhibiting hygroscopic properties and moderate basicity. This versatile chemical intermediate serves as a crucial building block in numerous industrial applications due to its unique dual functionality. The compound features a dimethylamino group attached to an ethanol backbone, providing both nucleophilic and hydrogen-bonding capabilities that make it valuable for synthesis and formulation work. Its molecular structure allows it to function effectively as both a catalyst and a reactive intermediate in various chemical processes. From a safety perspective, 2-(dimethylamino)ethanol requires careful handling as it is classified as a flammable liquid (Category 3) and corrosive to skin (Category 1B). The compound also presents acute toxicity hazards through multiple exposure routes. Proper personal protective equipment, adequate ventilation, and appropriate storage conditions are essential when working with this material. Its ADR Class 8 classification reflects its corrosive nature during transport. The compound finds extensive use in the production of pharmaceuticals, where it serves as an intermediate in the synthesis of antihistamines and other therapeutic agents. It is also employed in the manufacture of corrosion inhibitors for metalworking fluids and water treatment applications. Additionally, this chemical plays an important role in textile finishing processes and as a catalyst in polyurethane foam production. Like related compounds such as 2-(diethylamino)ethanol, it demonstrates excellent performance in applications requiring both amine and alcohol functionality. OYSI maintains reliable supply chains for 2-(dimethylamino)ethanol to support diverse industrial requirements across European markets.

Safety & Classification

Danger
Classification:

Flam. Liq. 3; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2051
ADR Class8
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name2-Dimethylaminoethanol
Marine PollutantNo

Frequently Asked Questions

What is 2-(dimethylamino)ethanol?

2-(dimethylamino)ethanol is an organic compound with the molecular formula C4H11NO and a molecular weight of 89.14 g/mol. It belongs to the class of tertiary amines and contains both amine and alcohol functional groups. This colorless liquid is commonly used as an intermediate in chemical synthesis and industrial applications. The substance is classified as corrosive to skin and poses acute toxicity hazards, requiring careful handling and proper safety measures during use.

What are the physicochemical properties of 2-(dimethylamino)ethanol?

2-(dimethylamino)ethanol is a colorless liquid at room temperature with a characteristic amine-like odor. It is highly water-soluble due to its polar amine and hydroxyl groups, making it miscible with water and many organic solvents. The compound has a boiling point around 134°C and exhibits hygroscopic properties, readily absorbing moisture from air. Its dual functionality as both an amine and alcohol gives it amphiphilic characteristics, making it useful as a solvent and chemical intermediate.

What is 2-(dimethylamino)ethanol used for?

2-(dimethylamino)ethanol serves as a versatile chemical intermediate in pharmaceutical synthesis, particularly for producing antihistamines and local anesthetics. It functions as a catalyst in polyurethane foam production and as a corrosion inhibitor in metalworking fluids. The compound is also used in the manufacture of surfactants, emulsifiers, and textile auxiliaries. Additionally, it finds applications in water treatment chemicals and as a neutralizing agent in various industrial processes due to its basic properties.

How to handle 2-(dimethylamino)ethanol safely?

2-(dimethylamino)ethanol requires careful handling due to its corrosive nature and acute toxicity. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or under fume hoods to avoid inhalation exposure. Avoid heat sources and ignition as it is classified as a flammable liquid. Handle containers carefully to prevent spills and ensure proper grounding during transfer operations to prevent static electricity buildup.

How to store 2-(dimethylamino)ethanol correctly?

2-(dimethylamino)ethanol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition. Keep containers in secondary containment to prevent environmental contamination in case of leaks. Store separately from strong acids, oxidizing agents, and incompatible materials. Maintain storage temperatures below 25°C and protect from direct sunlight. Ensure storage areas are equipped with appropriate fire suppression systems and spill response materials due to its flammable and corrosive properties.

What to do in case of contact with 2-(dimethylamino)ethanol?

Immediate action is required upon contact with 2-(dimethylamino)ethanol due to its corrosive properties. For skin contact, immediately flush with copious amounts of water for at least 15 minutes and remove contaminated clothing. In case of eye contact, rinse immediately with water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air and seek medical help if breathing difficulties occur. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for specific emergency procedures.

How to dispose of 2-(dimethylamino)ethanol appropriately?

2-(dimethylamino)ethanol must be disposed of as hazardous waste in accordance with local and national regulations. The substance cannot be discharged into sewers or waterways due to its toxicity and environmental impact. Contact licensed waste disposal companies for proper collection and treatment. Small quantities may require neutralization before disposal, but this should only be performed by trained personnel. Containers must be completely emptied and may require special handling as contaminated packaging. Always consult local environmental authorities for specific disposal requirements.

How to transport 2-(dimethylamino)ethanol?

2-(dimethylamino)ethanol is classified under ADR Class 8 (corrosive substances) with Packing Group II, indicating moderate danger level. Transportation requires appropriate UN-specification packaging and proper labeling with corrosive hazard markings. Vehicles must carry emergency response information and drivers need hazardous materials training. The substance requires segregation from incompatible materials during transport. Shipping documents must include proper shipping names, hazard classifications, and emergency contact information. Ensure compliance with international transport regulations for dangerous goods.

Is 2-(dimethylamino)ethanol subject to specific regulations?

2-(dimethylamino)ethanol is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification for hazard communication. The substance is not currently listed as a Substance of Very High Concern (SVHC) under REACH. Workplace exposure limits may apply under occupational health regulations. Import/export may require permits or notifications depending on jurisdiction. Industrial users must comply with emission controls and waste management regulations. Always verify current regulatory status as requirements may change over time.

Where to buy 2-(dimethylamino)ethanol in Europe?

2-(dimethylamino)ethanol is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. OYSI provides comprehensive product support including safety documentation, regulatory compliance assistance, and technical expertise. As a professional chemical distributor, OYSI ensures proper handling, packaging, and delivery according to ADR transport regulations. Contact OYSI directly for product availability, specifications, and quotations tailored to your specific industrial requirements and volume needs.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.