2-(dimethylamino)ethanol

C4H11NO

CAS108-01-0
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

Consulting for 2-(dimethylamino)ethanol

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Identification

CAS Number
108-01-0
EC Number
203-542-8
UN Number
2051
Index Number
603-047-00-0
PubChem CID
7902

Physical-chemical properties

Molecular Formula
C4H11NO
Molar Mass
89.14 g/mol
IUPAC Name
2-(dimethylamino)ethanol

Chemical Identifiers

InChI
InChI=1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3
InChI Key
UEEJHVSXFDXPFK-UHFFFAOYSA-N

Overview

2-(dimethylamino)ethanol (CAS 108-01-0) is a tertiary amine alcohol combining dimethylamino functionality with primary alcohol properties for industrial applications. This versatile chemical compound serves as an important intermediate in various industrial processes, offering dual functionality through its amine and alcohol groups. With the molecular formula C4H11NO and a molecular weight of 89.14 g/mol, this colorless liquid demonstrates significant reactivity due to its bifunctional nature. The presence of both tertiary amine and primary alcohol functionalities makes it particularly valuable in synthesis reactions, catalysis, and as a building block for more complex molecules. From a safety perspective, 2-(dimethylamino)ethanol requires careful handling due to its classification as a flammable liquid (Category 3) and skin corrosive material (Category 1B). The compound exhibits acute toxicity properties and necessitates appropriate personal protective equipment and ventilation systems during use. Its ADR Class 8 designation reflects its corrosive nature, requiring specialized storage and transport protocols. Industrial applications include its use as a catalyst in polyurethane foam production, where it facilitates the reaction between isocyanates and polyols. The compound also serves as an intermediate in pharmaceutical synthesis and finds application in water treatment formulations. Its chemical behavior is similar to related compounds such as 2-(diethylamino)ethanol, though with distinct reactivity profiles due to the different alkyl substituents on the nitrogen atom. The bifunctional nature of this amine alcohol makes it particularly suitable for applications requiring both basic catalytic properties and hydroxyl group reactivity. OYSI maintains reliable supply chains for this technical chemical, ensuring consistent availability for European industrial customers.

Safety & Classification

Danger
Classification:

Flam. Liq. 3; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2051
ADR Class8
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name2-Dimethylaminoethanol
Marine PollutantNo

Frequently Asked Questions

What is 2-(dimethylamino)ethanol?

2-(dimethylamino)ethanol is an organic chemical compound with the molecular formula C4H11NO and CAS number 108-01-0. This tertiary amine alcohol has a molecular weight of 89.14 g/mol and combines both amine and alcohol functional groups in its structure. It appears as a colorless to pale yellow liquid with a characteristic amine-like odor and is highly soluble in water due to its polar nature.

What are the physicochemical properties of 2-(dimethylamino)ethanol?

2-(dimethylamino)ethanol is a colorless to pale yellow liquid at room temperature with a distinctive amine-like, fishy odor. It has excellent water solubility due to its polar hydroxyl and amino groups, and is also miscible with most organic solvents. The compound is hygroscopic, readily absorbing moisture from air, and has basic properties due to the tertiary amine functionality.

What is 2-(dimethylamino)ethanol used for?

2-(dimethylamino)ethanol is primarily used as a chemical intermediate in pharmaceutical synthesis, particularly for producing antihistamines and local anesthetics. It serves as a catalyst in polyurethane foam production, a corrosion inhibitor in metalworking fluids, and an intermediate in manufacturing surfactants and emulsifiers. The compound is also used in water treatment applications and as a neutralizing agent in various industrial processes.

How to handle 2-(dimethylamino)ethanol safely?

2-(dimethylamino)ethanol requires careful handling due to its corrosive nature and multiple hazard classifications. Essential PPE includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or under fume hoods to avoid inhalation. Keep away from ignition sources as it's classified as Flam. Liq. 3, and ensure emergency eyewash stations and safety showers are readily accessible.

How to store 2-(dimethylamino)ethanol correctly?

2-(dimethylamino)ethanol should be stored in tightly sealed, corrosion-resistant containers in a cool, dry, well-ventilated area away from heat sources and ignition points. Keep containers upright and protected from direct sunlight and temperature extremes. Store separately from strong acids, oxidizing agents, and incompatible materials. Ensure storage areas have appropriate spill containment measures and are equipped with suitable fire suppression systems.

What to do in case of contact with 2-(dimethylamino)ethanol?

Immediate action is required due to the corrosive nature of 2-(dimethylamino)ethanol. For skin contact, immediately remove contaminated clothing and flush with plenty of water for at least 15 minutes. For eye contact, rinse immediately with water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention.

How to dispose of 2-(dimethylamino)ethanol properly?

2-(dimethylamino)ethanol must be disposed of as hazardous waste in accordance with local, national, and international regulations. The waste should be collected in appropriate containers, properly labeled, and handed over to licensed hazardous waste disposal companies. Incineration at high temperatures in authorized facilities is typically the preferred disposal method. Never dispose of this chemical through regular drains or municipal waste systems.

How to transport 2-(dimethylamino)ethanol?

2-(dimethylamino)ethanol is classified under ADR as Class 8 (corrosive substances), Packing Group II, indicating medium danger level during transport. It requires appropriate hazardous goods packaging, proper labeling with corrosive substance markings, and transport documentation. Vehicles must carry appropriate emergency equipment and drivers need ADR certification. The shipment must comply with quantity limitations and routing restrictions for corrosive materials.

Is 2-(dimethylamino)ethanol subject to specific regulations?

2-(dimethylamino)ethanol is subject to REACH regulation requiring registration for manufacture or import above one ton per year in the EU. It falls under CLP regulation with mandatory hazard classification and labeling requirements. The substance is not currently listed as SVHC (Substance of Very High Concern). Users must comply with occupational exposure limits, transport regulations (ADR), and local environmental discharge restrictions.

Where to buy 2-(dimethylamino)ethanol in Europe?

2-(dimethylamino)ethanol is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. OYSI provides this chemical compound with full regulatory compliance documentation, including safety data sheets and certificates of analysis. As a professional chemical distributor, OYSI ensures proper packaging, labeling, and transport arrangements according to applicable European regulations for corrosive substances.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.