Phenylmethanamine
C7H9N
phenylmethanamine
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Identification
- CAS Number
- 100-46-9
- EC Number
- 202-854-1
- UN Number
- 2735
- Index Number
- 612-047-00-X
- PubChem CID
- 7504
Physical-chemical properties
- Molecular Formula
- C7H9N
- Molar Mass
- 107.15 g/mol
- IUPAC Name
- phenylmethanamine
Chemical Identifiers
- InChI
- InChI=1S/C7H9N/c8-6-7-4-2-1-3-5-7/h1-5H,6,8H2
- InChI Key
- WGQKYBSKWIADBV-UHFFFAOYSA-N
Overview
Phenylmethanamine (CAS 100-46-9) is a primary aromatic amine with strong basic properties and high reactivity toward electrophilic compounds. This organic compound, also known by its IUPAC name phenylmethanamine, represents a fundamental building block in organic synthesis and industrial chemistry. With the molecular formula C7H9N and a molecular weight of 107.15 g/mol, this aromatic amine exhibits the characteristic properties of both benzene derivatives and primary amines. The compound features a benzyl group attached to an amino group, making it highly versatile for various chemical transformations and industrial applications. The substance is classified under multiple hazard categories, including Acute Toxicity Category 4 and Skin Corrosion 1B, requiring careful handling protocols. Its classification under ADR Class 8 indicates its corrosive nature, necessitating appropriate storage and transportation measures. The presence of GHS pictograms GHS07 and GHS05 with the signal word "Danger" emphasizes the importance of proper safety equipment and procedures when working with this material. Phenylmethanamine finds extensive use in pharmaceutical intermediates, where its reactive amine group serves as a key starting material for drug synthesis. The compound is also valuable in the production of specialty chemicals and as a reagent in organic synthesis. Industrial applications include its role in manufacturing processes that require primary aromatic amines, similar to applications involving compounds like N-cyclohexylcyclohexanamine, though with different reactivity profiles due to its aromatic nature. As a specialized chemical distributor, OYSI provides phenylmethanamine to European markets, ensuring compliance with regional safety and quality standards for industrial and research applications.
Safety & Classification
Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2735 |
| ADR Class | 8 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Benzylamin |
| Marine Pollutant | No |
Frequently Asked Questions
What is phenylmethanamine?
Phenylmethanamine is an organic chemical compound with the molecular formula C7H9N and CAS number 100-46-9. Also known as benzylamine, it belongs to the primary amine family and has a molecular weight of 107.15 g/mol. This aromatic amine consists of a benzyl group attached to an amino group, making it an important intermediate in organic synthesis and industrial applications.
What are the physicochemical properties of phenylmethanamine?
Phenylmethanamine is a colorless to pale yellow liquid at room temperature with a characteristic ammonia-like odor. It is miscible with water and most organic solvents due to its amine functionality. The compound has a boiling point around 184-185°C and is hygroscopic, readily absorbing moisture from air. Its basic nature (pKa ~9.3) makes it reactive with acids to form salts.
What is phenylmethanamine used for?
Phenylmethanamine serves as a versatile intermediate in pharmaceutical synthesis, particularly for manufacturing various drugs and active pharmaceutical ingredients. It is widely used in the production of surfactants, corrosion inhibitors, and rubber chemicals. Additionally, it finds applications in the synthesis of dyes, photographic chemicals, and as a catalyst in polymerization reactions in industrial settings.
How to handle phenylmethanamine safely?
Phenylmethanamine requires careful handling due to its corrosive nature and acute toxicity classification. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Avoid direct skin and eye contact, as the substance can cause severe burns and tissue damage.
How to store phenylmethanamine correctly?
Phenylmethanamine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep away from strong acids, oxidizing agents, and reactive metals to prevent dangerous reactions. Store in original containers with proper labeling and ensure adequate separation from incompatible materials. Maintain storage temperature below 25°C for optimal stability.
What to do in case of contact with phenylmethanamine?
Phenylmethanamine exposure requires immediate action due to its corrosive properties. For skin contact, immediately flush with plenty of water for at least 15 minutes and remove contaminated clothing. In case of eye contact, rinse thoroughly with water for 15-20 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly for all exposure routes, especially for burns or respiratory distress.
How to dispose of phenylmethanamine properly?
Phenylmethanamine disposal must comply with local and national hazardous waste regulations due to its classification as dangerous goods. The substance should be collected in appropriate containers and disposed of through licensed hazardous waste management companies. Never discharge into sewers, waterways, or soil. Incineration at high temperature in specialized facilities is typically the preferred disposal method for this organic compound.
How to transport phenylmethanamine?
Phenylmethanamine is classified as ADR Class 8 (corrosive substances), Packing Group III for transport purposes. It requires appropriate UN specification packaging and proper labeling with corrosive hazard markings. Transport vehicles must carry appropriate emergency equipment and documentation. Drivers need ADR certification, and the substance must be segregated from incompatible materials during transit according to dangerous goods regulations.
Is phenylmethanamine subject to specific regulations?
Phenylmethanamine is regulated under various European legislations including REACH registration requirements and CLP classification as Acute Tox. 4 and Skin Corr. 1B. It displays GHS07 and GHS05 pictograms with 'Danger' signal word. The substance is not currently listed as SVHC under REACH. Users must comply with occupational safety regulations and may need specific permits depending on quantities and applications.
Where to buy phenylmethanamine in Europe?
Phenylmethanamine is available through OYSI, a reliable European distributor of technical chemicals serving industrial customers across Europe. OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance support. As a specialized chemical distributor, OYSI ensures quality products and professional service for pharmaceutical, chemical manufacturing, and research applications throughout the European market.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.