Phenylmethanamine

C7H9N

phenylmethanamine

CAS100-46-9
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
100-46-9
EC Number
202-854-1
UN Number
2735
Index Number
612-047-00-X
PubChem CID
7504

Physical-chemical properties

Molecular Formula
C7H9N
Molar Mass
107.15 g/mol
IUPAC Name
phenylmethanamine

Chemical Identifiers

InChI
InChI=1S/C7H9N/c8-6-7-4-2-1-3-5-7/h1-5H,6,8H2
InChI Key
WGQKYBSKWIADBV-UHFFFAOYSA-N

Overview

Phenylmethanamine (CAS 100-46-9) is a primary aromatic amine featuring a benzyl group attached to an amino functional group, widely used as a chemical intermediate in pharmaceutical and polymer synthesis. This organic compound, also known by its IUPAC name phenylmethanamine, represents a fundamental building block in organic chemistry with the molecular formula C7H9N and a molecular weight of 107.15 g/mol. As a primary amine, it exhibits characteristic basic properties and high reactivity, making it valuable for numerous synthetic applications across various industrial sectors. The substance presents significant safety considerations due to its corrosive nature and acute toxicity profile. Classified under GHS pictograms GHS07 and GHS05 with the signal word "Danger," phenylmethanamine requires careful handling protocols. Its classification as Skin Corr. 1B indicates severe skin burns and eye damage potential, while its Acute Tox. 4 rating necessitates appropriate protective equipment and ventilation systems during use. The ADR class 8 designation confirms its corrosive transport classification. Industrial applications primarily focus on pharmaceutical intermediate synthesis, where phenylmethanamine serves as a precursor for various drug compounds. The chemical industry also utilizes this compound in polymer production and as a curing agent for epoxy resins. Unlike related compounds such as 2-(diethylamino)ethanol or N-cyclohexylcyclohexanamine, phenylmethanamine's aromatic structure provides unique reactivity patterns particularly valuable in aromatic substitution reactions and condensation processes. The compound's versatility extends to specialty chemical manufacturing, where its amine functionality enables formation of amides, imines, and other nitrogen-containing derivatives essential for advanced material applications. OYSI maintains reliable supply chains for phenylmethanamine, ensuring consistent availability for European industrial customers requiring this essential chemical intermediate.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2735
ADR Class8
Packing GroupIII
Tunnel CodeE
Proper Shipping NameBenzylamin
Marine PollutantNo

Frequently Asked Questions

What is phenylmethanamine?

Phenylmethanamine is a primary aromatic amine with the molecular formula C7H9N and CAS number 100-46-9. Also known as benzylamine, this organic compound features a benzyl group attached to an amino group. With a molecular weight of 107.15 g/mol, it serves as an important chemical intermediate in various industrial processes. It is classified as a corrosive substance with acute toxicity properties, requiring careful handling and appropriate safety measures during use.

What are the physicochemical properties of phenylmethanamine?

Phenylmethanamine is a colorless to pale yellow liquid at room temperature with a characteristic fishy, ammonia-like odor. It has a molecular formula of C7H9N and a molecular weight of 107.15 g/mol. The compound is miscible with water and most organic solvents due to its polar amino group. It exhibits basic properties typical of primary amines and can form salts with acids. Its volatility and strong odor make proper ventilation essential during handling.

What is phenylmethanamine used for?

Phenylmethanamine serves as a versatile chemical intermediate in pharmaceutical synthesis, particularly for manufacturing various drugs and active pharmaceutical ingredients. It is used in the production of surfactants, corrosion inhibitors, and rubber accelerators. The compound also finds applications in the synthesis of resins, dyes, and agricultural chemicals. Additionally, it serves as a catalyst in certain polymerization reactions and as a building block for specialty chemicals in various industrial processes.

How to handle phenylmethanamine safely?

Phenylmethanamine requires strict safety protocols due to its corrosive and toxic properties. Wear appropriate PPE including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation or use respiratory protection to avoid inhalation. Handle in a well-ventilated area or fume hood to prevent exposure to vapors. Avoid contact with skin, eyes, and clothing. Use non-sparking tools and equipment. Keep containers tightly closed when not in use and follow proper grounding procedures during transfer operations.

How to store phenylmethanamine correctly?

Phenylmethanamine must be stored in a cool, dry, well-ventilated area away from heat sources, ignition sources, and direct sunlight. Use corrosion-resistant containers with tight-fitting lids to prevent vapor escape. Store separately from oxidizing agents, acids, and incompatible materials. Maintain storage temperature below 25°C and ensure adequate containment measures for potential spills. Implement proper inventory rotation and regular container inspections. Storage areas should have appropriate fire suppression systems and emergency response equipment readily available.

What to do in case of contact with phenylmethanamine?

Phenylmethanamine contact requires immediate action due to its corrosive nature. For skin contact, immediately remove contaminated clothing and flush with copious amounts of water for at least 15 minutes. If eyes are affected, rinse thoroughly with clean water for 15-20 minutes while holding eyelids open. In case of inhalation, move to fresh air immediately. If ingested, do not induce vomiting; rinse mouth and seek immediate medical attention. Always consult a physician after any exposure incident.

How to dispose of phenylmethanamine properly?

Phenylmethanamine disposal must comply with local and national hazardous waste regulations due to its classification as a corrosive substance. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Do not discharge into sewers, waterways, or soil. Small quantities may require neutralization before disposal, but this should only be performed by trained personnel. Maintain proper documentation for waste tracking and ensure containers are properly labeled during the disposal process.

How to transport phenylmethanamine?

Phenylmethanamine is classified under ADR as Class 8 (corrosive substances), Packing Group III, requiring specific transport protocols. Use approved packaging materials resistant to corrosion and ensure proper labeling with hazard placards. Transport vehicles must carry appropriate emergency response information and spill cleanup materials. Drivers require ADR training certification. Avoid transport during extreme weather conditions and ensure proper securing of containers to prevent damage during transit. Follow all applicable dangerous goods transportation regulations.

Is phenylmethanamine subject to specific regulations?

Phenylmethanamine is regulated under various European frameworks including REACH registration requirements and CLP classification as Acute Tox. 4 and Skin Corr. 1B. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational exposure limits and workplace safety regulations. Transportation falls under ADR dangerous goods regulations. Some countries may have additional restrictions on purchase quantities or require permits for certain applications. Always verify current regulatory status before use.

Where to buy phenylmethanamine in Europe?

Phenylmethanamine is available through OYSI, a reliable European distributor of specialty chemicals serving industrial customers across the continent. OYSI provides high-quality phenylmethanamine with proper documentation, safety data sheets, and regulatory compliance support. As an established chemical distributor, OYSI ensures reliable supply chains and technical support for industrial applications. Contact OYSI directly to discuss specific requirements, quantities, and delivery options for phenylmethanamine and other specialty chemical needs throughout Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.