Sodium (4-aminophenyl)-hydroxyarsinate
C6H7AsNNaO3
sodium (4-aminophenyl)-hydroxyarsinate
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Identification
- CAS Number
- 127-85-5
- EC Number
- 204-869-9
- UN Number
- 2473
- Index Number
- 033-002-00-5
- PubChem CID
- 23670523
Physical-chemical properties
- Molecular Formula
- C6H7AsNNaO3
- Molar Mass
- 239.04 g/mol
- IUPAC Name
- sodium (4-aminophenyl)-hydroxyarsinate
Chemical Identifiers
- InChI
- InChI=1S/C6H8AsNO3.Na/c8-6-3-1-5(2-4-6)7(9,10)11;/h1-4H,8H2,(H2,9,10,11);/q;+1/p-1
- InChI Key
- OUFRIWNNMFWZTM-UHFFFAOYSA-M
Overview
Sodium (4-aminophenyl)-hydroxyarsinate (CAS 127-85-5) is an organoarsenic compound featuring both amino and hydroxyl functional groups with pharmaceutical applications. This organoarsenic compound, with the molecular formula C6H7AsNNaO3 and molecular weight of 239.04 g/mol, represents a specialized chemical intermediate that has found significant applications in pharmaceutical synthesis and research. The compound is also identified by its European Community number 204-869-9 and belongs to the class of aromatic arsenic derivatives that combine the structural features of aniline-based compounds with arsenic functionality. The presence of both amino and hydroxyarsinate groups in its structure makes this sodium salt particularly interesting from a synthetic chemistry perspective. Unlike simpler aromatic compounds such as 4-nitroaniline, this arsenic-containing derivative offers unique reactivity patterns that are valuable in specialized synthetic pathways. The compound's molecular architecture allows for multiple coordination modes and chemical transformations, making it a versatile building block in pharmaceutical chemistry. From a safety perspective, the compound is classified under ADR Class 6.1, indicating its toxic nature, which requires appropriate handling procedures and safety protocols during storage, transport, and use. Professional handling with adequate ventilation and personal protective equipment is essential when working with this material. Primary industrial applications include pharmaceutical intermediate synthesis, specialized research applications, and as a reagent in analytical chemistry. The compound has historically been important in the development of certain therapeutic agents and continues to serve as a valuable synthetic intermediate in pharmaceutical manufacturing processes. OYSI maintains reliable supply channels for sodium (4-aminophenyl)-hydroxyarsinate to support European pharmaceutical and chemical research industries with consistent quality and regulatory compliance.
Safety & Classification
No Hazard Classification
This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.
Transport (ADR)
| UN Number | 2473 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Natriumarsanilat, fest |
| Marine Pollutant | No |
Frequently Asked Questions
What is sodium (4-aminophenyl)-hydroxyarsinate?
Sodium (4-aminophenyl)-hydroxyarsinate is an organoarsenic compound with the molecular formula C6H7AsNNaO3 and CAS number 127-85-5. This chemical substance has a molecular weight of 239.04 g/mol and contains both an amino group and an arsenic atom in its structure. It belongs to the class of arylarsonic acid derivatives and is primarily used in specialized industrial applications requiring organoarsenic compounds.
What are the physicochemical properties of sodium (4-aminophenyl)-hydroxyarsinate?
Sodium (4-aminophenyl)-hydroxyarsinate is typically a solid crystalline compound at room temperature. As a sodium salt of an organoarsenic acid, it generally exhibits good water solubility due to its ionic nature. The compound contains an aromatic ring with an amino substituent, which influences its chemical reactivity and stability. Its exact color, odor, and specific solubility data would require analytical characterization.
What is sodium (4-aminophenyl)-hydroxyarsinate used for?
Sodium (4-aminophenyl)-hydroxyarsinate is used in specialized chemical synthesis and research applications where organoarsenic compounds are required. Its applications may include pharmaceutical intermediate synthesis, analytical chemistry procedures, and specialized industrial processes. The compound's unique structure combining aromatic, amino, and arsenic functionalities makes it valuable for specific chemical transformations and research purposes in laboratory and industrial settings.
How to handle sodium (4-aminophenyl)-hydroxyarsinate safely?
Sodium (4-aminophenyl)-hydroxyarsinate should be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Given its arsenic content, avoid skin contact and ingestion. Follow standard laboratory safety protocols for handling organoarsenic compounds and ensure proper training before use.
How to store sodium (4-aminophenyl)-hydroxyarsinate correctly?
Sodium (4-aminophenyl)-hydroxyarsinate should be stored in tightly sealed containers in a cool, dry place away from direct sunlight and heat sources. Keep the compound in its original packaging and ensure proper labeling. Store separately from incompatible materials such as strong oxidizers and acids. Maintain storage areas with adequate ventilation and implement appropriate access controls due to the arsenic content of the compound.
What to do in case of contact with sodium (4-aminophenyl)-hydroxyarsinate?
In case of skin contact with sodium (4-aminophenyl)-hydroxyarsinate, immediately wash the affected area with plenty of water for at least 15 minutes and remove contaminated clothing. For eye contact, flush with water for 15-20 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a poison control center or physician for arsenic-containing compounds.
How to dispose of sodium (4-aminophenyl)-hydroxyarsinate appropriately?
Sodium (4-aminophenyl)-hydroxyarsinate must be disposed of as hazardous waste due to its arsenic content. Contact licensed hazardous waste disposal companies for proper handling and disposal. Do not dispose of in regular waste streams or pour down drains. Follow local and national regulations for arsenic-containing compounds. Maintain proper documentation of disposal activities and ensure compliance with environmental protection requirements.
How to transport sodium (4-aminophenyl)-hydroxyarsinate?
Sodium (4-aminophenyl)-hydroxyarsinate is classified under ADR Class 6.1 (Toxic substances), Packaging Group III for transportation. This classification requires appropriate hazardous material packaging, labeling, and documentation. Shipments must comply with dangerous goods regulations and be handled by certified carriers. Proper shipping papers, emergency response information, and appropriate packaging specifications must be followed according to ADR requirements.
Is sodium (4-aminophenyl)-hydroxyarsinate subject to specific regulations?
Sodium (4-aminophenyl)-hydroxyarsinate is subject to chemical regulations including REACH registration requirements for commercial use in the European Union. The compound is not currently listed as a Substance of Very High Concern (SVHC). However, due to its arsenic content, it may be subject to additional national restrictions and occupational exposure limits. Users must comply with CLP regulation requirements for classification and labeling.
Where to buy sodium (4-aminophenyl)-hydroxyarsinate in Europe?
Sodium (4-aminophenyl)-hydroxyarsinate is available through OYSI, a trusted European distributor of specialty chemicals. OYSI provides reliable supply chains for organoarsenic compounds to laboratories and industrial customers across Europe. As a specialized chemical, availability may require advance ordering and proper documentation of intended use. Contact OYSI directly for specific product availability, packaging options, and technical support for your application requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.