4-nitroaniline

4-nitroaniline is an organic chemical compound with the molecular formula C6H6N2O2 and CAS number 100-01-6. It belongs to the family of nitroanilines, which are aromatic compounds containing both amino (-NH2) and nitro (-NO2) functional groups. With a molecular weight of 138.12 g/mol, this compound appears as yellow crystalline needles or powder and is commonly used as an intermediate in chemical synthesis, particularly in the production of dyes, pharmaceuticals, and other organic compounds.

4-nitroaniline is a yellow crystalline solid at room temperature with a melting point around 148-149°C. It has limited solubility in water but dissolves well in organic solvents like ethanol, acetone, and benzene. The compound exhibits a characteristic aromatic odor and is stable under normal conditions. Its molecular structure features a benzene ring substituted with an amino group at position 1 and a nitro group at position 4, giving it distinctive chemical reactivity patterns typical of substituted anilines.

4-nitroaniline is primarily used as a chemical intermediate in the synthesis of various industrial products. It serves as a key building block in the production of azo dyes, particularly yellow and orange colorants used in textile and printing industries. The compound is also utilized in pharmaceutical manufacturing as an intermediate for drug synthesis, in the production of antioxidants, and in the manufacture of rubber chemicals and corrosion inhibitors for various industrial applications.

4-nitroaniline should be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation of dust or vapors. Avoid skin and eye contact, and prevent ingestion. Use non-sparking tools and equipment, as the compound can be sensitive to static electricity. Always wash hands thoroughly after handling and ensure proper training on chemical safety procedures before use.

4-nitroaniline should be stored in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and incompatible materials. Keep containers tightly sealed and protected from moisture to prevent degradation. Store separately from strong oxidizing agents, acids, and bases to avoid dangerous reactions. The storage area should be equipped with appropriate spill containment measures and fire protection systems. Maintain proper labeling and inventory control according to local regulations.

In case of skin contact with 4-nitroaniline, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush eyes with clean water for at least 15 minutes and seek immediate medical attention. If inhaled, move the person to fresh air and monitor breathing. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a poison control center or physician for specific medical advice.

4-nitroaniline must be disposed of according to local and national hazardous waste regulations. It cannot be disposed of in regular waste streams due to its chemical nature. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may be suitable for incineration at high temperatures in approved facilities. Never discharge into sewers, waterways, or soil. Maintain proper documentation of disposal activities and ensure compliance with all applicable environmental regulations.

4-nitroaniline is classified under ADR class 6.1 (toxic substances), packing group II, requiring specific transport regulations. It must be packaged in approved containers with proper labeling and documentation. Transportation should be conducted by trained personnel with appropriate safety equipment and emergency response procedures. Vehicles must carry proper placards and shipping papers. Ensure compliance with international transport regulations including ADR for road transport, IMDG for sea transport, and IATA for air transport when applicable.

4-nitroaniline is subject to various chemical regulations including REACH registration requirements in the European Union for manufacturing or importing quantities above specified thresholds. It must be classified and labeled according to CLP regulation standards. The compound is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational health and safety regulations, environmental protection laws, and transportation requirements. Always check current regulatory status as requirements may change.

4-nitroaniline is available through OYSI, a leading European distributor of chemical products. OYSI provides high-quality chemical intermediates to industrial customers across Europe with proper documentation and regulatory compliance. As a specialized chemical distributor, OYSI ensures reliable supply chains and technical support for customers requiring 4-nitroaniline for various industrial applications. Contact OYSI directly for specific product specifications, availability, and procurement requirements to meet your industrial needs.