1,2-diphenylguanidine
C13H13N3
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Identification
- CAS Number
- 102-06-7
- EC Number
- 203-002-1
- UN Number
- 2811
- Index Number
- 612-149-00-4
- PubChem CID
- 7594
Physical-chemical properties
- Molecular Formula
- C13H13N3
- Molar Mass
- 211.26 g/mol
- IUPAC Name
- 1,2-diphenylguanidine
Chemical Identifiers
- InChI
- InChI=1S/C13H13N3/c14-13(15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H,(H3,14,15,16)
- InChI Key
- OWRCNXZUPFZXOS-UHFFFAOYSA-N
Overview
1,2-Diphenylguanidine (CAS 102-06-7) is an organic guanidine derivative compound featuring two phenyl groups attached to the guanidine backbone, primarily used as a rubber accelerator. This crystalline organic compound with molecular formula C13H13N3 and molecular weight 211.26 g/mol serves as a critical intermediate in rubber vulcanization processes and various industrial applications. As a diphenyl-substituted guanidine, it belongs to a class of compounds known for their catalytic properties in polymer chemistry, sharing certain chemical characteristics with other aromatic compounds such as 4-aminophenol in terms of phenyl ring reactivity. The compound presents moderate safety considerations, classified under multiple hazard categories including reproductive toxicity (Repr. 2), acute toxicity (Acute Tox. 4), and skin irritation properties (Skin Irrit. 2). The GHS08, GHS07, and GHS09 pictograms indicate health hazards, general hazards, and environmental concerns respectively. Its ADR classification as Class 6.1 reflects its toxic nature during transportation, requiring appropriate handling protocols and protective equipment during industrial use. In industrial applications, 1,2-diphenylguanidine functions primarily as a secondary accelerator in rubber vulcanization, enhancing the cross-linking process in natural and synthetic rubber compounds. It also serves as an intermediate in pharmaceutical synthesis and as a catalyst in certain polymerization reactions. The compound's effectiveness in rubber processing makes it valuable for tire manufacturing, industrial rubber goods, and specialty elastomer production. The aquatic chronic toxicity classification (Aquatic Chronic 2) necessitates careful environmental management during handling and disposal. Proper storage conditions and worker protection measures are essential when working with this material. OYSI supplies 1,2-diphenylguanidine to meet European industrial requirements, ensuring compliance with REACH regulations and maintaining high-quality standards for technical applications across the rubber and chemical processing industries.
Safety & Classification
Repr. 2; Acute Tox. 4 *; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2811 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | 1,3-Diphenylguanidin |
| Marine Pollutant | No |
Frequently Asked Questions
What is 1,2-diphenylguanidine?
1,2-diphenylguanidine is an organic chemical compound with the molecular formula C13H13N3 and CAS number 102-06-7. This guanidine derivative has a molecular weight of 211.26 g/mol and appears as a white to off-white crystalline powder. It belongs to the class of substituted guanidines where two phenyl groups are attached to the nitrogen atoms. The compound is primarily used in industrial applications, particularly in rubber manufacturing as an accelerator for vulcanization processes.
What are the physicochemical properties of 1,2-diphenylguanidine?
1,2-diphenylguanidine is a white to light yellow crystalline solid at room temperature with a molecular weight of 211.26 g/mol. The compound has low solubility in water but dissolves well in organic solvents such as alcohol and acetone. It has a melting point typically around 147-150°C and demonstrates thermal stability under normal conditions. The substance is odorless or has a very faint characteristic odor and maintains its crystalline structure under proper storage conditions.
What is 1,2-diphenylguanidine used for?
1,2-diphenylguanidine is primarily used as a rubber accelerator in the vulcanization process of natural and synthetic rubbers. It serves as a secondary accelerator, often combined with other accelerators to improve curing efficiency and final product properties. The compound is also utilized in the production of rubber goods including tires, hoses, belts, and various molded rubber products. Additionally, it finds applications in some specialty chemical formulations and as an intermediate in organic synthesis processes.
How to handle 1,2-diphenylguanidine safely?
1,2-diphenylguanidine requires careful handling due to its classification as Acute Tox. 4, Skin Irrit. 2, Eye Irrit. 2, and STOT SE 3. Always wear appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Ensure adequate ventilation in work areas and avoid generating dust. Prevent skin and eye contact, and avoid inhalation of particles. Use in well-ventilated areas or under local exhaust ventilation to minimize exposure risks.
How to store 1,2-diphenylguanidine correctly?
1,2-diphenylguanidine should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed and store in original packaging or suitable chemical-resistant containers. The storage area should be separated from incompatible materials such as strong acids and oxidizing agents. Maintain storage temperatures below 25°C when possible and ensure the storage area is equipped with appropriate spill containment measures and emergency equipment.
What to do in case of contact with 1,2-diphenylguanidine?
In case of skin contact with 1,2-diphenylguanidine, immediately wash the affected area with plenty of soap and water for at least 15 minutes and remove contaminated clothing. For eye contact, rinse immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air immediately. If swallowed, do not induce vomiting and seek immediate medical attention. In all cases of exposure, consult a physician and provide the safety data sheet.
How to dispose of 1,2-diphenylguanidine appropriately?
1,2-diphenylguanidine must be disposed of in accordance with local, national, and international waste regulations as a hazardous chemical waste. Contact licensed waste disposal companies for proper treatment and disposal. Do not discharge into drains, waterways, or soil due to its Aquatic Chronic 2 classification. Contaminated packaging should also be treated as hazardous waste. Consider waste minimization through recovery or recycling where technically and economically feasible, following appropriate safety protocols.
How to transport 1,2-diphenylguanidine?
1,2-diphenylguanidine is classified under ADR Class 6.1 (toxic substances), Packing Group III, requiring specific transport regulations for hazardous materials. Packages must be properly labeled with appropriate hazard labels and UN identification numbers. Transport vehicles must carry appropriate emergency equipment and documentation. Drivers must have valid ADR training certificates. Ensure packages are secure, properly sealed, and protected from damage during transport. Follow all applicable national and international dangerous goods transport regulations.
Is 1,2-diphenylguanidine subject to specific regulations?
1,2-diphenylguanidine is subject to REACH regulation in Europe and must comply with CLP classification requirements, displaying Warning signal word and pictograms GHS07, GHS08, and GHS09. The substance is classified as Repr. 2, requiring special attention to reproductive health risks. While not currently listed as SVHC, it requires safety data sheets and appropriate risk assessments. Users must comply with occupational exposure limits and implement appropriate risk management measures according to local chemical safety regulations.
Where to buy 1,2-diphenylguanidine in Europe?
1,2-diphenylguanidine is available through OYSI, a European distributor of specialty chemicals serving industrial customers across Europe. OYSI provides technical-grade 1,2-diphenylguanidine with complete documentation including safety data sheets and certificates of analysis. As an established chemical distributor, OYSI ensures regulatory compliance and reliable supply chain management. Contact OYSI directly for pricing, availability, packaging options, and technical support to meet your specific application requirements in rubber processing and other industrial uses.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.