Sodium 2-fluoroacetate

C2H2FNaO2

sodium 2-fluoroacetate

CAS62-74-8
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
62-74-8
EC Number
200-548-2
UN Number
2629
Index Number
607-169-00-5
PubChem CID
16212360

Physical-chemical properties

Molecular Formula
C2H2FNaO2
Molar Mass
100.02 g/mol
IUPAC Name
sodium 2-fluoroacetate

Chemical Identifiers

InChI
InChI=1S/C2H3FO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
InChI Key
JGFYQVQAXANWJU-UHFFFAOYSA-M

Overview

Sodium 2-fluoroacetate (CAS 62-74-8) is a highly toxic fluorinated organic salt with potent rodenticidal properties and extreme hazard classification. This fluorinated acetate compound represents one of the most hazardous substances in industrial chemistry, classified under multiple acute toxicity categories with Danger signal word and requiring stringent handling protocols. The molecular structure features a fluorine atom substituted at the alpha position of acetate, creating a metabolic poison that interferes with cellular respiration through fluorocitrate formation in the Krebs cycle. The compound appears as a white, odorless crystalline powder that is highly soluble in water, making it particularly dangerous due to its ease of absorption and distribution in biological systems. Its classification under ADR Class 6.1 reflects its severe toxicity profile, requiring specialized transport and storage conditions. The substance carries GHS06 skull and crossbones pictogram for acute toxicity and GHS09 environmental hazard symbol, indicating significant risks to aquatic ecosystems. Unlike less hazardous compounds such as N-methylaniline or phenylhydrazine, sodium 2-fluoroacetate requires exceptional safety measures including specialized personal protective equipment, controlled access areas, and emergency response protocols. Industrial applications are strictly regulated and typically limited to specialized pest control formulations in agricultural settings, research applications in biochemical studies, and controlled manufacturing processes where its unique metabolic interference properties are specifically required. Due to its extreme toxicity and regulatory restrictions, this substance requires comprehensive documentation, specialized handling expertise, and compliance with international chemical safety regulations. OYSI provides this material exclusively to qualified industrial customers with appropriate safety credentials and regulatory approvals.

Safety & Classification

Danger
Classification:

Acute Tox. 2 *; Acute Tox. 1; Acute Tox. 2 *; Aquatic Acute 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H330

Fatal if inhaled.

H310

Fatal in contact with skin.

H300

Fatal if swallowed.

H400

Very toxic to aquatic life.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Fatal

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2629
ADR Class6.1
Packing GroupI
Tunnel CodeC/E
Proper Shipping NameNatriumfluoracetat
Marine PollutantNo

Frequently Asked Questions

What is sodium 2-fluoroacetate?

Sodium 2-fluoroacetate is a highly toxic organic sodium salt with the molecular formula C2H2FNaO2 and CAS number 62-74-8. This compound has a molecular weight of 100.02 g/mol and is classified as an extremely hazardous substance with Acute Toxicity Category 1 and 2 classifications. It poses severe risks to human health and aquatic environments, requiring strict handling protocols and safety measures in all applications.

What are the physicochemical properties of sodium 2-fluoroacetate?

Sodium 2-fluoroacetate is typically a white crystalline solid that is highly soluble in water due to its ionic nature. The compound is stable under normal conditions but extremely toxic even in small quantities. Its fluorine content makes it particularly dangerous as it can interfere with cellular metabolism. The substance should be handled with extreme caution due to its high toxicity profile and potential environmental impact.

What is sodium 2-fluoroacetate used for?

Sodium 2-fluoroacetate is primarily used as a research chemical and analytical standard in laboratory settings. Due to its extreme toxicity, its applications are heavily restricted and limited to specialized scientific research, particularly in biochemical studies and toxicological research. Any use requires strict regulatory compliance and specialized safety protocols. Industrial applications are extremely limited due to safety and regulatory constraints.

How to handle sodium 2-fluoroacetate safely?

Sodium 2-fluoroacetate requires maximum safety precautions including full personal protective equipment: chemical-resistant gloves, safety goggles, face shield, and protective clothing. Work must be conducted in a well-ventilated fume hood or controlled environment. Avoid any skin contact, inhalation, or ingestion. Only trained personnel should handle this substance. Emergency procedures and antidotes should be immediately available. All work areas must be properly decontaminated after use.

How to store sodium 2-fluoroacetate correctly?

Sodium 2-fluoroacetate must be stored in a secure, locked area with restricted access in original, tightly sealed containers. Storage areas should be cool, dry, and well-ventilated, away from incompatible materials and food products. Containers must be properly labeled with hazard warnings. Storage facilities should comply with local regulations for highly toxic substances and include appropriate spill containment measures and emergency response equipment.

What to do in case of contact with sodium 2-fluoroacetate?

Immediate medical attention is critical for any exposure to sodium 2-fluoroacetate. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with water for 15 minutes. Never induce vomiting if ingested. Contact emergency services immediately and provide the safety data sheet to medical personnel. Time is critical due to the substance's extreme toxicity.

How to dispose of sodium 2-fluoroacetate properly?

Sodium 2-fluoroacetate disposal requires specialized hazardous waste treatment through licensed waste management companies. The substance cannot be disposed of through normal waste streams due to its extreme toxicity and environmental hazards. All containers, contaminated materials, and residues must be treated as hazardous waste. Disposal must comply with local, national, and international regulations for highly toxic substances and require proper documentation and chain of custody.

How to transport sodium 2-fluoroacetate?

Sodium 2-fluoroacetate is classified under ADR Class 6.1 (Toxic substances), Packing Group I, indicating maximum danger level for transport. Transportation requires specialized packaging, proper labeling with GHS06 and GHS09 pictograms, and compliance with dangerous goods regulations. Only authorized carriers with proper training and equipment can transport this substance. All transport documentation must include emergency response information and proper shipping names.

Is sodium 2-fluoroacetate subject to particular regulations?

Sodium 2-fluoroacetate is subject to extensive regulatory controls under REACH, CLP, and national chemical legislation due to its extreme toxicity. The substance requires registration for commercial use, safety data sheets, and strict handling protocols. Many jurisdictions have severe restrictions or prohibitions on its sale and use. Users must comply with occupational safety regulations, environmental protection laws, and may require special permits or licenses.

Where to buy sodium 2-fluoroacetate in Europe?

Sodium 2-fluoroacetate is available through specialized chemical distributors like OYSI, which serves the European market with high-quality chemical products. Due to the substance's extreme toxicity and regulatory restrictions, purchases typically require verification of legitimate research purposes, proper licensing, and compliance documentation. Buyers must demonstrate appropriate safety protocols and may need special permits depending on local regulations and intended use.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.