N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine
C13H22NO3PS
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Identification
- CAS Number
- 22224-92-6
- EC Number
- 244-848-1
- UN Number
- 2783
- Index Number
- 015-123-00-5
- PubChem CID
- 31070
Physical-chemical properties
- Molecular Formula
- C13H22NO3PS
- Molar Mass
- 303.36 g/mol
- IUPAC Name
- N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine
Chemical Identifiers
- InChI
- InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)
- InChI Key
- ZCJPOPBZHLUFHF-UHFFFAOYSA-N
Overview
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine (CAS 22224-92-6) is an organophosphorus compound with acute toxicity properties and environmental hazard classification. This specialized organophosphorus derivative represents a complex chemical structure combining phosphoryl, phenoxy, and amine functionalities within a single molecule. With the molecular formula C13H22NO3PS and a molecular weight of 303.36 g/mol, this compound exhibits significant biological activity that necessitates careful handling protocols. The presence of both methylsulfanyl and ethoxy substituents on the phosphoryl group contributes to its unique chemical profile and reactivity patterns. The compound carries serious safety considerations, classified under multiple acute toxicity categories (Acute Tox. 2) for oral, dermal, and inhalation exposure routes. It also presents environmental concerns with Aquatic Acute 1 and Aquatic Chronic 1 classifications, indicating high toxicity to aquatic organisms. The GHS06 and GHS09 pictograms reflect its dual hazard profile encompassing both human health risks and environmental dangers. Transportation falls under ADR Class 6.1, designating it as a toxic substance requiring specialized logistics protocols. Industrial applications typically center around specialized synthesis processes where the compound serves as an intermediate or reagent in pharmaceutical research and agrochemical development. Its structural complexity makes it valuable for studies involving organophosphorus chemistry and biological activity screening. Unlike simpler aromatic amines such as N-methylaniline, this compound's phosphoryl functionality provides unique reactivity patterns essential for specific synthetic pathways. The compound's European Community number (244-848-1) ensures regulatory compliance across EU markets. Professional users require comprehensive safety training and appropriate containment systems when handling this material, given its classification profile and environmental impact potential. OYSI maintains technical-grade supplies of this specialized organophosphorus compound for qualified industrial and research applications throughout Europe.
Safety & Classification
Acute Tox. 2; Acute Tox. 2; Acute Tox. 2; Eye Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2783 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | Fenamiphos (ISO) |
| Marine Pollutant | No |
Frequently Asked Questions
What is N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine?
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine is an organophosphorus compound with the molecular formula C13H22NO3PS and CAS number 22224-92-6. This chemical substance has a molecular weight of 303.36 g/mol and belongs to the class of phosphoryl compounds containing both amine and phenoxy functional groups. It is classified as highly hazardous with acute toxicity properties and environmental risks, requiring careful handling and specialized safety measures in industrial applications.
What are the physicochemical properties of N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine?
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine is an organophosphorus compound with a molecular weight of 303.36 g/mol and molecular formula C13H22NO3PS. The compound contains phosphorus, sulfur, nitrogen, and oxygen atoms within its structure, featuring ethoxy, methyl, and methylsulfanyl substituents. Specific physical properties such as melting point, boiling point, and solubility characteristics should be obtained from detailed safety data sheets for precise handling requirements.
What is N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine used for?
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine is primarily used in specialized chemical synthesis and research applications due to its organophosphorus structure. The compound may serve as an intermediate in pharmaceutical research, agrochemical development, or specialized industrial processes. Given its high toxicity classification and environmental hazard profile, its applications are typically restricted to professional settings with appropriate safety controls and regulatory compliance measures in place.
How to handle N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine safely?
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine requires strict safety protocols due to its Acute Tox. 2 classification and eye irritant properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and appropriate respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin and eye contact, inhalation, and ingestion. Emergency shower and eyewash stations should be readily accessible, and only trained personnel should handle this substance.
How to store N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine correctly?
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine must be stored in a secure, well-ventilated area away from incompatible materials and ignition sources. The storage area should be equipped with appropriate containment measures and restricted access due to its high toxicity classification. Containers must be tightly sealed and properly labeled with hazard information. Temperature and humidity should be controlled according to manufacturer specifications, and regular inventory checks should ensure container integrity and proper segregation from other chemicals.
What to do in case of contact with N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine?
Immediate medical attention is required for any contact with N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine due to its Acute Tox. 2 classification. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek emergency medical care. Contact poison control centers promptly.
How to dispose of N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine appropriately?
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine must be disposed of as hazardous waste through licensed waste management companies due to its high toxicity and environmental hazard classification. The substance cannot be discharged to sewers, soil, or waterways given its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Disposal must comply with local, national, and EU regulations including the Waste Framework Directive. Empty containers should also be treated as hazardous waste and handled accordingly.
How to transport N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine?
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine is classified under ADR Class 6.1 (toxic substances) Packing Group II, indicating significant transport hazards. Transportation requires specialized packaging, labeling with appropriate hazard placards, and documentation complying with dangerous goods regulations. Only certified carriers trained in hazardous materials transport should handle shipments. Proper segregation from incompatible materials, food products, and animal feed is mandatory during transport. Emergency response information must accompany all shipments.
Is N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine subject to specific regulations?
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine is subject to comprehensive EU chemical regulations including REACH registration requirements and CLP classification standards. The substance must be handled according to its hazard classifications (Acute Tox. 2, Eye Irrit. 2, Aquatic hazards) with appropriate risk management measures. While not currently listed as SVHC, it may be subject to use restrictions, authorization requirements, or notification obligations depending on specific applications and quantities. Users must ensure regulatory compliance and maintain safety data sheets.
Where to buy N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine in Europe?
N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine is available through OYSI, a specialized European distributor of technical chemical products. OYSI provides professional-grade chemicals with proper documentation, safety data sheets, and regulatory compliance support. Given the substance's high hazard classification and transport restrictions, procurement requires verification of legitimate use, appropriate handling capabilities, and regulatory compliance. Contact OYSI's technical team for availability, specifications, and application-specific guidance for this specialized organophosphorus compound.
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N-[ethoxy-(3-methyl-4-methylsulfanylphenoxy)phosphoryl]propan-2-amine is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.