4-methoxyaniline

4-methoxyaniline is an aromatic amine compound with the molecular formula C7H9NO and CAS number 104-94-9. This organic chemical features a benzene ring substituted with both an amino group (-NH2) and a methoxy group (-OCH3) in para position. With a molecular weight of 123.15 g/mol, it serves as an important intermediate in chemical synthesis and industrial applications.

4-methoxyaniline is typically a crystalline solid at room temperature, appearing as white to light gray crystals or powder. It has a characteristic amine-like odor and is moderately soluble in water, with better solubility in organic solvents such as ethanol and acetone. The compound is sensitive to light and air oxidation, which can cause discoloration over time.

4-methoxyaniline is primarily used as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It serves as a building block for azo dyes, particularly in the textile industry, and is utilized in the production of various organic compounds. The substance is also employed in research and development applications for chemical synthesis and analytical chemistry purposes.

4-methoxyaniline requires strict safety measures due to its high toxicity classification (Acute Tox. 1 and 2). Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact completely, as the substance poses severe health risks upon exposure.

4-methoxyaniline should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep the substance away from oxidizing agents and incompatible materials. Storage areas must be secure and accessible only to trained personnel due to the compound's high toxicity. Maintain temperatures below 25°C for optimal stability.

Immediate action is critical due to the substance's high toxicity. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with clean water and seek medical attention. If inhaled, move to fresh air immediately. For any exposure, contact emergency services and provide the safety data sheet to medical personnel.

4-methoxyaniline must be disposed of as hazardous waste according to local and EU regulations. Never dispose of the substance through regular waste streams or pour down drains due to its environmental toxicity (Aquatic Acute 1). Contact licensed hazardous waste disposal companies for proper treatment and disposal. Follow all applicable waste codes and documentation requirements for hazardous chemical waste.

4-methoxyaniline is classified as dangerous goods under ADR regulations as Class 6.1 (toxic substances), Packing Group III. Transportation requires proper packaging, labeling with appropriate hazard placards, and documentation including transport documents. Only certified carriers experienced in handling toxic materials should transport this substance. Ensure compliance with all applicable transport regulations for dangerous goods.

4-methoxyaniline is subject to various chemical regulations including REACH registration requirements in the EU and CLP classification for hazard communication. The substance requires safety data sheets and proper labeling with GHS pictograms (GHS06, GHS08, GHS09) and 'Danger' signal word. While not currently listed as SVHC, its high toxicity classification requires strict compliance with occupational safety regulations.

4-methoxyaniline is available through OYSI, a specialized European distributor of chemical products. As a professional chemical supplier, OYSI provides quality 4-methoxyaniline with proper documentation, safety data sheets, and regulatory compliance for industrial and research applications. Contact OYSI directly for availability, specifications, and delivery options across European markets.