2-methyl-3,4-dinitrophenol

C7H6N2O5

CAS1335-85-9
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
1335-85-9
UN Number
1598
Index Number
609-020-00-X
PubChem CID
3032394

Physical-chemical properties

Molecular Formula
C7H6N2O5
Molar Mass
198.13 g/mol
IUPAC Name
2-methyl-3,4-dinitrophenol

Chemical Identifiers

InChI
InChI=1S/C7H6N2O5/c1-4-6(10)3-2-5(8(11)12)7(4)9(13)14/h2-3,10H,1H3
InChI Key
IUOFDOCUNLJHFO-UHFFFAOYSA-N

Overview

2-methyl-3,4-dinitrophenol (CAS 1335-85-9) is a nitrated phenolic compound with high toxicity and mutagenic properties. This dinitrophenol derivative represents a specialized chemical intermediate characterized by its methyl substituent at the ortho position and two nitro groups at the 3,4 positions on the phenol ring. With a molecular formula of C7H6N2O5 and molecular weight of 198.13 g/mol, this compound exhibits significant hazard properties that require careful handling protocols in industrial applications. The substance presents multiple safety concerns, classified with GHS pictograms including skull and crossbones (GHS06), health hazard (GHS08), corrosion (GHS05), and environmental hazard (GHS09). Its classification as Acute Toxicity Category 1 and 2, along with Mutagenicity Category 2 designation, necessitates stringent safety measures during storage, handling, and transportation. The compound falls under ADR Class 6.1 for toxic substances, reflecting its potential health risks through various exposure routes. Industrial applications of 2-methyl-3,4-dinitrophenol primarily include its use as a chemical intermediate in organic synthesis, particularly in the production of specialized dyes, pigments, and pharmaceutical intermediates. The compound also serves in research and development applications for creating novel chemical entities. Unlike simpler compounds such as 2-chloroacetaldehyde, this dinitrophenol requires specialized handling equipment and environmental controls due to its enhanced toxicity profile. Manufacturing facilities utilizing this compound must implement comprehensive safety protocols, including appropriate ventilation systems, personal protective equipment, and waste disposal procedures to ensure worker safety and environmental compliance. OYSI maintains availability of 2-methyl-3,4-dinitrophenol for qualified industrial customers with appropriate handling capabilities and regulatory compliance.

Safety & Classification

Danger
Classification:

Muta. 2; Acute Tox. 2 *; Acute Tox. 1; Acute Tox. 2 *; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1; A...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H341

Suspected of causing genetic defects.

H330

Fatal if inhaled.

H310

Fatal in contact with skin.

H300

Fatal if swallowed.

H315

Causes skin irritation.

H318

Causes serious eye damage.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Fatal

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1598
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameDinitro-o-cresole, Isomere oder Isomerengemisch, fest
Marine PollutantNo

Frequently Asked Questions

What is 2-methyl-3,4-dinitrophenol?

2-methyl-3,4-dinitrophenol is an organic chemical compound with the molecular formula C7H6N2O5 and CAS number 1335-85-9. This nitrophenol derivative has a molecular weight of 198.13 g/mol and belongs to the family of substituted phenols. It is characterized by the presence of two nitro groups and one methyl group attached to a phenol ring, making it a highly hazardous substance classified with multiple danger categories including acute toxicity and mutagenicity.

What are the physicochemical properties of 2-methyl-3,4-dinitrophenol?

2-methyl-3,4-dinitrophenol is typically a solid crystalline substance at room temperature with a characteristic yellow to orange color. The compound has a molecular weight of 198.13 g/mol and contains both hydrophilic (phenolic hydroxyl, nitro groups) and lipophilic (methyl group) functional groups. Its nitro substituents make it highly polar and potentially explosive under certain conditions. The presence of multiple electron-withdrawing groups significantly affects its chemical reactivity and stability properties.

What is 2-methyl-3,4-dinitrophenol used for?

2-methyl-3,4-dinitrophenol is primarily used as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a precursor for the production of various fine chemicals, dyes, and specialized pharmaceutical compounds. The compound may also be utilized in analytical chemistry as a reagent or standard. Due to its high toxicity profile and strict regulatory controls, its applications are limited to specialized industrial processes requiring appropriate safety measures and trained personnel.

How to handle 2-methyl-3,4-dinitrophenol safely?

2-methyl-3,4-dinitrophenol requires strict safety protocols due to its acute toxicity and mutagenic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, full-face respirator, and protective clothing. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact completely, and ensure emergency shower and eyewash stations are readily accessible. Only trained personnel should handle this substance following established safety procedures.

How to store 2-methyl-3,4-dinitrophenol correctly?

2-methyl-3,4-dinitrophenol must be stored in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and incompatible materials. Use original containers or approved secondary containment made of compatible materials. Store separately from reducing agents, strong bases, and organic solvents to prevent dangerous reactions. Access should be restricted to authorized personnel only, and storage areas must be clearly labeled with appropriate hazard warnings and equipped with spill containment measures.

What to do in case of contact with 2-methyl-3,4-dinitrophenol?

2-methyl-3,4-dinitrophenol exposure requires immediate emergency response due to its high toxicity. For skin contact, immediately remove contaminated clothing and flush with copious amounts of water for at least 15 minutes. In case of eye contact, rinse immediately with water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always contact poison control or emergency services after any exposure incident.

How to dispose of 2-methyl-3,4-dinitrophenol properly?

2-methyl-3,4-dinitrophenol disposal must comply with local, national, and European waste regulations as hazardous chemical waste. The substance cannot be disposed of through normal waste streams due to its toxicity and environmental hazard classification. Disposal must be performed by licensed hazardous waste contractors through approved methods such as high-temperature incineration in specialized facilities. Containers must be properly labeled, and waste documentation must accompany all disposal activities according to regulatory requirements.

How to transport 2-methyl-3,4-dinitrophenol?

2-methyl-3,4-dinitrophenol is classified as ADR Class 6.1 (Toxic substances), Packing Group II, requiring specialized transport procedures. Packages must meet UN specification requirements and display appropriate hazard labels and markings. Transport vehicles must carry emergency response information and appropriate safety equipment. Drivers require ADR certification for dangerous goods transport. Shipping documentation must include proper shipping names, hazard classifications, and emergency contact information according to international dangerous goods regulations.

Is 2-methyl-3,4-dinitrophenol subject to specific regulations?

2-methyl-3,4-dinitrophenol is subject to comprehensive European chemical regulations including REACH registration requirements and CLP classification obligations. The substance's multiple hazard classifications (mutagenicity, acute toxicity, skin sensitization) trigger specific labeling, safety data sheet, and risk assessment requirements. Users must comply with occupational exposure limits, worker protection measures, and environmental discharge restrictions. Import, use, and distribution may require permits or notifications depending on quantities and applications within EU member states.

Where to buy 2-methyl-3,4-dinitrophenol in Europe?

2-methyl-3,4-dinitrophenol is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substance supply. OYSI provides comprehensive regulatory support, proper packaging, and compliant documentation for this highly regulated substance. As an established chemical distributor, OYSI ensures product quality, regulatory compliance, and professional handling throughout the supply chain. Contact OYSI directly for availability, technical specifications, and purchasing requirements for 2-methyl-3,4-dinitrophenol in European markets.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.