2-hydroxy-2-methylpropanenitrile

2-hydroxy-2-methylpropanenitrile is an organic chemical compound with the molecular formula C4H7NO and CAS number 75-86-5. This nitrile compound has a molecular weight of 85.1 g/mol and contains both hydroxyl and nitrile functional groups. It is classified as highly toxic with acute toxicity categories 1 and 2, and poses significant environmental hazards to aquatic life. The substance requires careful handling due to its dangerous classification under GHS regulations.

2-hydroxy-2-methylpropanenitrile is a chemical compound with molecular formula C4H7NO and molecular weight 85.1 g/mol. As a nitrile compound containing a hydroxyl group, it likely exists as a liquid at room temperature with characteristic nitrile odor. The presence of both polar hydroxyl and nitrile groups suggests moderate solubility in polar solvents. Specific physical properties such as boiling point, density, and exact solubility parameters should be confirmed through technical data sheets.

2-hydroxy-2-methylpropanenitrile serves as an important intermediate in organic synthesis and chemical manufacturing processes. Its dual functional groups (hydroxyl and nitrile) make it valuable for producing pharmaceuticals, agrochemicals, and specialty chemicals. The compound is typically used in professional industrial settings for chemical synthesis reactions, particularly where both nitrile and alcohol functionalities are required. Due to its high toxicity classification, its use is restricted to specialized industrial applications with proper safety controls.

2-hydroxy-2-methylpropanenitrile requires extreme caution during handling due to its Acute Tox. 1 and 2 classifications. Essential PPE includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas or fume hoods. Avoid skin contact, inhalation, and ingestion completely. Work in controlled environments with emergency shower and eyewash stations readily available. Only trained personnel should handle this substance, following strict safety protocols and having emergency response procedures in place.

2-hydroxy-2-methylpropanenitrile must be stored in tightly sealed containers in cool, dry, well-ventilated areas away from heat sources and incompatible materials. As a highly toxic substance, it requires secure storage with restricted access and appropriate warning labels. Keep containers upright and check regularly for leaks. Storage areas should have spill containment measures and be separated from food, feed, and drinking water. Maintain inventory records and ensure compatibility with container materials to prevent degradation.

Immediate action is critical due to the substance's high toxicity classification. For skin contact, remove contaminated clothing and flush affected area with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, rinse thoroughly with water for several minutes, removing contact lenses if present. If ingested, do not induce vomiting. Seek immediate medical attention in all cases of exposure, providing safety data sheet information to medical personnel.

2-hydroxy-2-methylpropanenitrile must be disposed of as hazardous waste through licensed waste management companies due to its high toxicity and environmental hazard classifications. Never dispose of this substance in regular waste, sewers, or the environment. Contact certified hazardous waste disposal services that can handle Acute Tox. 1 materials and aquatic pollutants. Follow local and European waste regulations (EU Waste Framework Directive) and maintain disposal documentation for regulatory compliance and traceability.

2-hydroxy-2-methylpropanenitrile is classified as ADR Class 6.1 (toxic substances) Packing Group I, indicating high toxicity requiring strict transport regulations. It must be transported in approved packaging with proper hazard labels (GHS06 skull and crossbones, GHS09 environment). Transport requires trained drivers with ADR certification and appropriate transport documents. Vehicles must carry emergency equipment and follow designated routes. Only authorized carriers experienced in handling highly toxic materials should transport this substance.

2-hydroxy-2-methylpropanenitrile is subject to comprehensive chemical regulations including EU REACH registration requirements and CLP classification as a highly toxic substance. While not currently listed as SVHC, its Acute Tox. 1 classification means it falls under strict handling, labeling, and reporting requirements. Companies must comply with occupational safety regulations, environmental protection laws, and transport regulations (ADR). Regular safety assessments and worker health monitoring may be mandatory depending on usage quantities and exposure potential.

2-hydroxy-2-methylpropanenitrile is available through specialized chemical distributors like OYSI, a European distributor of technical chemicals. Due to its high toxicity classification and regulatory requirements, this substance is only supplied to qualified industrial customers with proper handling capabilities. Suppliers must verify customer qualifications, intended use, and safety infrastructure before delivery. OYSI provides technical support and regulatory documentation to ensure compliant procurement and handling of this hazardous chemical substance.