Potassium 2-fluoroacetate

C2H2FKO2

potassium 2-fluoroacetate

CAS23745-86-0
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
23745-86-0
UN Number
2628
Index Number
607-082-00-2
PubChem CID
23685976

Physical-chemical properties

Molecular Formula
C2H2FKO2
Molar Mass
116.13 g/mol
IUPAC Name
potassium 2-fluoroacetate

Chemical Identifiers

InChI
InChI=1S/C2H3FO2.K/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
InChI Key
XOIIGTWTZBPWBS-UHFFFAOYSA-M

Overview

Potassium 2-fluoroacetate (CAS 23745-86-0) is an organofluorine salt compound with high acute toxicity and significant environmental hazard potential. This potassium salt of 2-fluoroacetic acid represents a specialized chemical intermediate within the organofluorine compound family, distinguished by its molecular formula C2H2FKO2 and molecular weight of 116.13 g/mol. The compound exhibits severe toxicological properties, classified under Acute Toxicity Category 2 and requiring stringent handling protocols due to its danger classification and associated GHS06 skull and crossbones pictogram. Additionally, its Aquatic Acute 1 classification and GHS09 environmental pictogram reflect significant environmental concerns requiring careful waste management and containment measures. The compound's structure incorporates a fluorine atom adjacent to the carboxylate group, similar to its parent acid 2-fluoroacetic acid, which contributes to its biological activity and toxicological profile. This fluoroacetate moiety interferes with cellular metabolism through disruption of the citric acid cycle, making it extremely hazardous to biological systems. Transportation regulations classify it under ADR Class 6.1, emphasizing the critical importance of proper packaging, labeling, and handling procedures throughout the supply chain. Industrial applications primarily focus on specialized synthetic chemistry where the compound serves as a fluorinating reagent or intermediate in pharmaceutical research and agrochemical development. It also finds limited use in biochemical research applications where controlled fluoroacetate exposure studies are conducted under strict safety protocols. OYSI maintains availability of potassium 2-fluoroacetate for qualified industrial customers with appropriate safety infrastructure and regulatory compliance capabilities.

Safety & Classification

Danger
Classification:

Acute Tox. 2 *; Aquatic Acute 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H300

Fatal if swallowed.

H400

Very toxic to aquatic life.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2628
ADR Class6.1
Packing GroupI
Tunnel CodeC/E
Proper Shipping NameKaliumfluoracetat
Marine PollutantNo

Frequently Asked Questions

What is potassium 2-fluoroacetate?

Potassium 2-fluoroacetate is a highly toxic organic salt with the molecular formula C2H2FKO2 and CAS number 23745-86-0. This chemical compound has a molecular weight of 116.13 g/mol and belongs to the fluoroacetate family. It is classified as acutely toxic (Category 2) and poses significant environmental hazards to aquatic life. The substance requires extreme caution during handling due to its high toxicity profile and potential health risks.

What are the physicochemical properties of potassium 2-fluoroacetate?

Potassium 2-fluoroacetate is a crystalline solid at room temperature with high water solubility due to its ionic nature. The compound typically appears as white to off-white crystals and is odorless or has a slight characteristic odor. It is highly soluble in water and polar solvents, making it readily bioavailable. The substance is stable under normal conditions but decomposes when heated, potentially releasing toxic fluorine compounds.

What is potassium 2-fluoroacetate used for?

Potassium 2-fluoroacetate is primarily used as a research chemical in biochemical and toxicological studies. It serves as a metabolic poison in scientific research to study cellular respiration and enzyme inhibition mechanisms. The compound is also utilized in laboratory settings for analytical chemistry applications and as a reference standard. Due to its extreme toxicity, its use is strictly limited to controlled professional environments with appropriate safety measures.

How to handle potassium 2-fluoroacetate safely?

Potassium 2-fluoroacetate requires extreme safety precautions due to its acute toxicity classification. Essential PPE includes chemical-resistant gloves, safety goggles, and laboratory coats. Work must be conducted in a well-ventilated fume hood to prevent inhalation exposure. Avoid skin contact, ingestion, and inhalation at all costs. Only trained personnel should handle this substance, and emergency procedures must be readily available. All work surfaces should be decontaminated after use.

How to store potassium 2-fluoroacetate correctly?

Potassium 2-fluoroacetate must be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly sealed and clearly labeled with appropriate hazard warnings. Storage should be in a locked, secure area accessible only to authorized personnel due to the substance's high toxicity. Avoid exposure to heat, moisture, and strong acids. Implement appropriate containment measures to prevent environmental release and ensure compliance with local storage regulations.

What to do in case of contact with potassium 2-fluoroacetate?

Potassium 2-fluoroacetate exposure requires immediate emergency response due to its acute toxicity. For skin contact, immediately remove contaminated clothing and flush with copious amounts of water for at least 15 minutes. If inhaled, move to fresh air immediately. In case of eye contact, rinse thoroughly with water. For ingestion, do not induce vomiting and seek immediate medical attention. Contact poison control centers and emergency services immediately for any exposure incident.

How to dispose of potassium 2-fluoroacetate properly?

Potassium 2-fluoroacetate disposal requires specialized hazardous waste management due to its acute toxicity and environmental hazard classification. The substance must be disposed of through licensed hazardous waste contractors following local and European waste regulations. Never dispose of in regular waste streams or pour down drains due to aquatic toxicity. Containerize waste properly with appropriate labeling and documentation. Consult local environmental authorities for specific disposal requirements and authorized treatment facilities.

How to transport potassium 2-fluoroacetate?

Potassium 2-fluoroacetate is classified under ADR Class 6.1 (toxic substances) Packing Group I, indicating maximum danger level for toxic materials. Transportation requires specialized packaging meeting UN specification standards and appropriate hazard labeling including GHS06 and GHS09 pictograms. Only authorized carriers with proper training and equipment should handle transport. All shipments must comply with international dangerous goods regulations and include proper shipping documentation and emergency response information.

Is potassium 2-fluoroacetate subject to specific regulations?

Potassium 2-fluoroacetate is subject to strict European chemical regulations under REACH and CLP frameworks due to its acute toxicity classification. The substance requires appropriate classification, labeling, and safety data sheets compliant with CLP regulation. While not currently listed as SVHC, its Acute Tox. 2 classification imposes significant handling and use restrictions. Users must comply with occupational exposure limits, environmental protection measures, and proper notification requirements under applicable chemical safety legislation.

Where to buy potassium 2-fluoroacetate in Europe?

Potassium 2-fluoroacetate is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI ensures compliance with all regulatory requirements and provides appropriate documentation including safety data sheets. Due to the substance's high toxicity classification, purchases are restricted to qualified professional users with legitimate research or analytical applications. Contact OYSI directly for availability, technical specifications, and regulatory compliance support for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.