Phenylmethanol
C7H8O
phenylmethanol
Consulting for Phenylmethanol
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Identification
- CAS Number
- 100-51-6
- EC Number
- 202-859-9
- UN Number
- Index Number
- 603-057-00-5
- PubChem CID
- 244
Physical-chemical properties
- Molecular Formula
- C7H8O
- Molar Mass
- 108.14 g/mol
- IUPAC Name
- phenylmethanol
Chemical Identifiers
- InChI
- InChI=1S/C7H8O/c8-6-7-4-2-1-3-5-7/h1-5,8H,6H2
- InChI Key
- WVDDGKGOMKODPV-UHFFFAOYSA-N
Overview
Phenylmethanol (CAS 100-51-6) is an aromatic primary alcohol with characteristic benzyl structure and moderate toxicity profile. Phenylmethanol, also known by its IUPAC designation, represents a fundamental aromatic alcohol compound widely utilized across various industrial applications. With the molecular formula C7H8O and a molecular weight of 108.14 g/mol, this benzyl alcohol derivative serves as a crucial intermediate in organic synthesis and manufacturing processes. The compound features a phenyl group directly attached to a methanol unit, creating a structure that combines the stability of aromatic systems with the reactivity of primary alcohols. From a safety perspective, phenylmethanol is classified under the GHS system with the warning signal word and GHS07 pictogram. The substance presents moderate hazards including acute toxicity (Category 4), eye irritation (Category 2), and skin sensitization properties (Category 1B). These characteristics necessitate appropriate handling procedures and personal protective equipment during industrial operations. The compound's hazard profile differs from related substances such as 4-nitrophenol, which carries additional concerns due to its nitro group functionality. Industrial applications of phenylmethanol span multiple sectors, particularly in pharmaceutical intermediates where its benzyl structure proves valuable for drug synthesis. The compound also finds extensive use in fragrance and flavor industries, leveraging its aromatic properties for consumer products. Additionally, phenylmethanol serves as a solvent and chemical intermediate in specialty chemical manufacturing, often utilized alongside compounds like tetrachlorosilane in silicon-based applications. OYSI maintains reliable supply chains for phenylmethanol, ensuring consistent availability for European industrial customers requiring this essential aromatic alcohol intermediate.
Safety & Classification
Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1B
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Frequently Asked Questions
What is phenylmethanol?
Phenylmethanol is an aromatic primary alcohol with the molecular formula C7H8O and CAS number 100-51-6. Also known as benzyl alcohol, it consists of a benzene ring attached to a methanol group. With a molecular weight of 108.14 g/mol, this organic compound appears as a colorless liquid with a mild pleasant aromatic odor. It is classified as a potentially hazardous substance requiring careful handling due to its acute toxicity, eye irritation, and skin sensitization properties.
What are the physicochemical properties of phenylmethanol?
Phenylmethanol is a colorless liquid at room temperature with a characteristic mild, pleasant aromatic odor. It has a molecular weight of 108.14 g/mol and the molecular formula C7H8O. The compound is moderately soluble in water and miscible with most organic solvents including ethanol and ether. It has a boiling point of approximately 205°C and a melting point around -15°C, making it stable under normal storage and handling conditions.
What is phenylmethanol used for?
Phenylmethanol serves as an important intermediate in pharmaceutical manufacturing, particularly in the synthesis of various medications and active pharmaceutical ingredients. It is widely used in the cosmetics and personal care industry as a preservative and fragrance component. Additionally, it functions as a solvent for various chemical processes, a precursor for benzyl esters, and finds applications in the production of specialty chemicals, flavoring agents, and as a starting material for organic synthesis reactions.
How to handle phenylmethanol safely?
Phenylmethanol requires careful handling due to its Acute Tox. 4, Eye Irrit. 2, and Skin Sens. 1B classifications. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Avoid direct skin and eye contact, and prevent ingestion. The substance carries the GHS07 pictogram and 'Warning' signal word, indicating moderate hazard levels requiring standard laboratory safety precautions.
How to store phenylmethanol correctly?
Phenylmethanol should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep containers upright and properly labeled according to GHS requirements. Store away from incompatible materials such as strong oxidizing agents and acids. Maintain storage temperatures below 25°C when possible and ensure adequate secondary containment. Regular inspection of containers for leaks or damage is recommended to prevent accidental exposure or environmental release.
What to do in case of contact with phenylmethanol?
Phenylmethanol contact requires immediate action due to its irritating and sensitizing properties. For skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention while providing the safety data sheet to medical personnel.
How to dispose of phenylmethanol appropriately?
Phenylmethanol disposal must comply with local and European waste regulations as it is classified as hazardous waste. Do not dispose of it down drains, in soil, or with regular waste. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small laboratory quantities may be incinerated at authorized high-temperature facilities. Always consult the safety data sheet and local environmental authorities for specific disposal requirements. Proper waste classification codes must be used when arranging disposal services.
How to transport phenylmethanol?
Phenylmethanol transport follows standard chemical shipping procedures as it does not fall under specific ADR dangerous goods classifications for routine transport. However, proper packaging in suitable containers with appropriate labeling according to GHS requirements is mandatory. Use UN-specification packaging when required by local regulations. Ensure vehicles are properly ventilated and drivers are informed about the product's hazards. Always include safety data sheets and emergency contact information during transport, and comply with national and international shipping regulations.
Is phenylmethanol subject to specific regulations?
Phenylmethanol is regulated under European REACH and CLP regulations requiring proper registration, classification, and labeling. It must be labeled with GHS07 pictogram and 'Warning' signal word due to its Acute Tox. 4, Eye Irrit. 2, and Skin Sens. 1B classifications. The substance is not currently listed as SVHC under REACH. Users must maintain safety data sheets, implement appropriate risk management measures, and comply with occupational exposure limits where established by national authorities.
Where to buy phenylmethanol in Europe?
Phenylmethanol is available through OYSI, a specialized European distributor of technical chemicals serving industrial and professional customers across Europe. OYSI provides high-quality phenylmethanol with complete documentation including certificates of analysis and safety data sheets. As an established chemical distributor, OYSI ensures reliable supply chains and regulatory compliance for European markets. Contact OYSI directly for specific grades, quantities, packaging options, and delivery arrangements to meet your technical requirements and applications.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.