Azepan-2-one
C6H11NO
azepan-2-one
Consulting for Azepan-2-one
Our experts support you with application, dosage, and compliance.
Identification
- CAS Number
- 105-60-2
- EC Number
- 203-313-2
- UN Number
- Index Number
- 613-069-00-2
- PubChem CID
- 7768
Physical-chemical properties
- Molecular Formula
- C6H11NO
- Molar Mass
- 113.16 g/mol
- IUPAC Name
- azepan-2-one
Chemical Identifiers
- InChI
- InChI=1S/C6H11NO/c8-6-4-2-1-3-5-7-6/h1-5H2,(H,7,8)
- InChI Key
- JBKVHLHDHHXQEQ-UHFFFAOYSA-N
Overview
Azepan-2-one (CAS 105-60-2) is a seven-membered cyclic amide with notable solvent properties and moderate toxicity characteristics. This organic compound, also known by its IUPAC designation azepan-2-one, belongs to the lactam family of chemicals with the molecular formula C6H11NO and a molecular weight of 113.16 g/mol. As a cyclic amide, azepan-2-one exhibits unique chemical properties that make it valuable in various industrial applications, particularly as a polar aprotic solvent and chemical intermediate. The compound presents moderate safety concerns, classified under GHS07 pictogram with a "Warning" signal word. Its hazard profile includes acute toxicity category 4, skin and eye irritation category 2, and specific target organ toxicity category 3. These classifications necessitate appropriate handling procedures and personal protective equipment during industrial use. Unlike more hazardous chemicals such as tetrachlorosilane, azepan-2-one's toxicity profile allows for broader industrial applications with proper safety measures. Azepan-2-one finds primary application as a solvent in polymer chemistry, particularly in the production of polyamides and other high-performance materials. Its excellent solvating properties make it suitable for dissolving various polymers and facilitating chemical reactions that require polar aprotic conditions. Additionally, the compound serves as an intermediate in pharmaceutical synthesis and specialty chemical manufacturing. The seven-membered ring structure of azepan-2-one provides distinct advantages over smaller ring lactams, offering improved stability and specific reactivity patterns that are valuable in synthetic chemistry applications. OYSI maintains reliable supply chains for azepan-2-one, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate.
Safety & Classification
Acute Tox. 4 *; Acute Tox. 4 *; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Frequently Asked Questions
What is azepan-2-one?
Azepan-2-one is a seven-membered cyclic amide, also known as caprolactam, with the molecular formula C6H11NO and CAS number 105-60-2. This organic compound has a molecular weight of 113.16 g/mol and belongs to the lactam family of chemicals. It is classified as a moderately hazardous substance with acute toxicity and irritant properties, requiring careful handling in industrial applications.
What are the physicochemical properties of azepan-2-one?
Azepan-2-one is typically a white crystalline solid at room temperature with a characteristic amine-like odor. It exhibits good solubility in water and polar organic solvents due to its amide functional group. The compound has a melting point around 69-71°C and is hygroscopic, meaning it readily absorbs moisture from air. Its cyclic structure provides stability while maintaining reactivity for polymerization processes.
What is azepan-2-one used for?
Azepan-2-one is primarily used as a monomer in the production of nylon-6 through ring-opening polymerization. It serves as a key raw material in the manufacture of synthetic fibers, engineering plastics, and films used in textiles, automotive parts, and packaging applications. The compound is also utilized in the production of specialty chemicals and as an intermediate in pharmaceutical synthesis.
How to handle azepan-2-one safely?
Azepan-2-one requires careful handling due to its Acute Tox. 4 classification and irritant properties. Wear appropriate PPE including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation to prevent inhalation exposure. Avoid skin and eye contact, and do not ingest. Work in well-ventilated areas and have eyewash stations readily available for emergency use.
How to store azepan-2-one correctly?
Azepan-2-one should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly closed to prevent moisture absorption due to its hygroscopic nature. Store away from strong oxidizing agents and incompatible materials. Maintain storage temperature below 25°C and ensure proper labeling according to GHS requirements with Warning signal word.
What to do in case of contact with azepan-2-one?
In case of skin contact with azepan-2-one, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes and seek medical attention. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical assistance.
How to dispose of azepan-2-one appropriately?
Azepan-2-one waste must be disposed of according to local and national hazardous waste regulations. Do not discharge into drains, waterways, or soil. Collect waste in properly labeled, compatible containers and arrange disposal through licensed hazardous waste contractors. Small quantities may be incinerated at high temperatures in approved facilities. Always consult local environmental authorities for specific disposal requirements.
How to transport azepan-2-one?
Azepan-2-one transportation requirements depend on quantity and packaging, as specific ADR classification data is not available for this substance. Follow general chemical transport regulations, using appropriate packaging that prevents leakage and contamination. Ensure proper labeling with GHS pictogram GHS07 and Warning signal word. Consult transport authorities for specific classification requirements and use certified dangerous goods packaging when required.
Is azepan-2-one subject to specific regulations?
Azepan-2-one is subject to REACH regulation in Europe and must be registered for commercial use. It is classified under CLP regulation with specific hazard classes including Acute Tox. 4, STOT SE 3, Skin Irrit. 2, and Eye Irrit. 2. The substance is not currently listed as SVHC. Manufacturers and importers must comply with safety data sheet requirements and workplace exposure limit regulations.
Where to buy azepan-2-one in Europe?
Azepan-2-one is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. OYSI provides high-quality azepan-2-one with complete regulatory documentation, safety data sheets, and technical support. Contact OYSI directly for availability, specifications, and delivery options to your location within Europe for both small-scale and bulk requirements.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.