2-methylbenzene-1,3-diamine

C7H10N2

CAS823-40-5
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
823-40-5
EC Number
212-513-9
UN Number
3077
Index Number
612-111-00-7
PubChem CID
13205

Physical-chemical properties

Molecular Formula
C7H10N2
Molar Mass
122.17 g/mol
IUPAC Name
2-methylbenzene-1,3-diamine

Chemical Identifiers

InChI
InChI=1S/C7H10N2/c1-5-6(8)3-2-4-7(5)9/h2-4H,8-9H2,1H3
InChI Key
RLYCRLGLCUXUPO-UHFFFAOYSA-N

Overview

2-methylbenzene-1,3-diamine (CAS 823-40-5) is an aromatic diamine compound with mutagenic properties and acute toxicity characteristics. This organic chemical compound, also known by its EC number 212-513-9, belongs to the family of substituted benzene diamines with a molecular formula of C7H10N2 and molecular weight of 122.17 g/mol. The compound features two amino groups positioned at the 1 and 3 positions of a benzene ring, with an additional methyl substituent at position 2, creating a distinctive aromatic diamine structure that exhibits specific reactivity patterns. From a safety perspective, 2-methylbenzene-1,3-diamine requires careful handling due to its classification under multiple hazard categories. The substance is classified as Mutagenic Category 2, indicating potential genetic toxicity, and Acute Toxic Category 4 through multiple exposure routes. Additionally, it presents skin sensitization risks and carries aquatic chronic toxicity concerns, reflected in its GHS08, GHS07, and GHS09 pictogram requirements and ADR Class 9 transportation classification. In industrial applications, this aromatic diamine serves primarily as an intermediate in the synthesis of dyes, pigments, and specialty chemicals. The compound's dual amino functionality makes it valuable in polymer chemistry for producing polyurethanes and epoxy resins, while its aromatic structure contributes to the development of advanced materials with enhanced thermal stability. Unlike simpler compounds such as 1,4-dichlorobenzene, this diamine offers more complex reactivity patterns suitable for sophisticated chemical transformations. OYSI maintains reliable supply chains for 2-methylbenzene-1,3-diamine, ensuring consistent availability for European industrial customers requiring this specialized aromatic diamine intermediate.

Safety & Classification

Warning
Classification:

Muta. 2; Acute Tox. 4 *; Acute Tox. 4 *; Skin Sens. 1; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H341

Suspected of causing genetic defects.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H317

May cause an allergic skin reaction.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2,6-Toluylendiamin, fest
Marine PollutantNo

Frequently Asked Questions

What is 2-methylbenzene-1,3-diamine?

2-methylbenzene-1,3-diamine is an aromatic diamine compound with the molecular formula C7H10N2 and CAS number 823-40-5. This organic chemical features a benzene ring substituted with a methyl group and two amino groups in specific positions. With a molecular weight of 122.17 g/mol, it belongs to the family of substituted anilines and serves as an important intermediate in various chemical synthesis processes.

What are the physicochemical properties of 2-methylbenzene-1,3-diamine?

2-methylbenzene-1,3-diamine is typically a solid crystalline compound at room temperature with characteristic amine properties. As an aromatic diamine, it exhibits basic behavior due to its two amino groups and shows solubility in polar solvents. The compound has a molecular weight of 122.17 g/mol and contains both aromatic and aliphatic functionalities, making it reactive toward electrophiles and suitable for various chemical transformations.

What is 2-methylbenzene-1,3-diamine used for?

2-methylbenzene-1,3-diamine serves primarily as an intermediate in the synthesis of dyes, pigments, and pharmaceutical compounds. Its diamine structure makes it valuable for producing polyurethanes, epoxy curing agents, and various polymer materials. The compound is also utilized in the manufacture of hair dyes and colorants for industrial applications, where its aromatic structure provides stability and color-forming properties.

How to handle 2-methylbenzene-1,3-diamine safely?

Safe handling of 2-methylbenzene-1,3-diamine requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Acute Tox. 4 and Skin Sens. 1 classifications. Work in well-ventilated areas or use fume extraction systems to minimize inhalation exposure. Avoid direct skin contact and ensure proper hygiene practices. The compound's mutagenic properties (Muta. 2) necessitate strict adherence to safety protocols.

How to store 2-methylbenzene-1,3-diamine correctly?

2-methylbenzene-1,3-diamine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers protected from light and moisture to prevent degradation. Store separately from strong oxidizers, acids, and other reactive chemicals. Maintain proper labeling with GHS pictograms (GHS07, GHS08, GHS09) and ensure storage areas comply with local chemical storage regulations.

What to do in case of contact with 2-methylbenzene-1,3-diamine?

In case of skin contact with 2-methylbenzene-1,3-diamine, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush with clean water for 15-20 minutes and seek medical attention. If inhaled, move to fresh air immediately. Given its acute toxicity and sensitizing properties, seek medical advice promptly after any significant exposure incident.

How to dispose of 2-methylbenzene-1,3-diamine appropriately?

2-methylbenzene-1,3-diamine must be disposed of as hazardous chemical waste through authorized waste management companies specializing in toxic and mutagenic substances. Never discharge into drains, soil, or waterways due to its Aquatic Chronic 2 classification. Follow local and EU waste regulations, including proper waste classification codes. Ensure proper documentation and chain of custody for hazardous waste disposal to comply with environmental protection requirements.

How to transport 2-methylbenzene-1,3-diamine?

2-methylbenzene-1,3-diamine is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. Use appropriate UN-specification packaging and ensure proper labeling with hazard labels and shipping documentation. Transport vehicles must comply with ADR requirements for Class 9 materials. Drivers need appropriate ADR training certification, and transport documents must include emergency response information and proper shipping names.

Is 2-methylbenzene-1,3-diamine subject to specific regulations?

2-methylbenzene-1,3-diamine is subject to REACH regulation requiring registration for manufacture or import above one tonne per year. Under CLP regulation, it must be classified and labeled according to its hazard profile (Muta. 2, Acute Tox. 4, Skin Sens. 1, Aquatic Chronic 2). While not currently listed as SVHC, its mutagenic properties require compliance with occupational exposure limits and worker protection measures under EU chemical safety legislation.

Where to buy 2-methylbenzene-1,3-diamine in Europe?

2-methylbenzene-1,3-diamine is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. OYSI provides this compound with proper regulatory documentation, safety data sheets, and technical support. As a professional chemical distributor, OYSI ensures compliance with REACH registration requirements and provides reliable supply chains for customers requiring this aromatic diamine intermediate for their manufacturing processes.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.