2-methylbenzene-1,3-diamine

C7H10N2

CAS823-40-5
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
823-40-5
EC Number
212-513-9
UN Number
3077
Index Number
612-111-00-7
PubChem CID
13205

Physical-chemical properties

Molecular Formula
C7H10N2
Molar Mass
122.17 g/mol
IUPAC Name
2-methylbenzene-1,3-diamine

Chemical Identifiers

InChI
InChI=1S/C7H10N2/c1-5-6(8)3-2-4-7(5)9/h2-4H,8-9H2,1H3
InChI Key
RLYCRLGLCUXUPO-UHFFFAOYSA-N

Overview

2-methylbenzene-1,3-diamine (CAS 823-40-5) is an aromatic diamine compound with mutagenic properties and skin sensitization potential. This organic chemical, also known by its IUPAC designation 2-methylbenzene-1,3-diamine, belongs to the family of substituted aromatic diamines with the molecular formula C7H10N2 and a molecular weight of 122.17 g/mol. The compound features a benzene ring substituted with a methyl group at position 2 and amino groups at positions 1 and 3, creating a unique structural arrangement that influences its chemical reactivity and applications. The substance is classified under multiple hazard categories including mutagenicity category 2, acute toxicity category 4, skin sensitization category 1, and aquatic chronic toxicity category 2. These classifications necessitate careful handling procedures and appropriate safety measures during storage, transport, and use. The compound carries GHS pictograms GHS08, GHS07, and GHS09, with a "Warning" signal word, and is classified under ADR class 9 for transportation purposes. In industrial applications, 2-methylbenzene-1,3-diamine serves primarily as an intermediate in the synthesis of dyes, pigments, and polymer materials. Its diamine functionality makes it particularly valuable in the production of polyamides and as a curing agent for epoxy resins. The compound also finds use in the manufacture of specialty chemicals where its specific substitution pattern provides desired properties. While structurally different from compounds like 6-amino-N-methylnaphthalene-2-sulfonamide, it shares similar applications in dye chemistry and industrial synthesis. OYSI maintains reliable supply chains for 2-methylbenzene-1,3-diamine across European markets, ensuring consistent availability for qualified industrial customers with appropriate handling capabilities.

Safety & Classification

Warning
Classification:

Muta. 2; Acute Tox. 4 *; Acute Tox. 4 *; Skin Sens. 1; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H341

Suspected of causing genetic defects.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H317

May cause an allergic skin reaction.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2,6-Toluylendiamin, fest
Marine PollutantNo

Frequently Asked Questions

What is 2-methylbenzene-1,3-diamine?

2-methylbenzene-1,3-diamine is an aromatic diamine compound with the molecular formula C7H10N2 and CAS number 823-40-5. This organic chemical features a benzene ring substituted with two amino groups at positions 1 and 3, and a methyl group at position 2. With a molecular weight of 122.17 g/mol, it belongs to the class of substituted aromatic amines and is classified as a hazardous substance requiring appropriate safety measures during handling and storage.

What are the physicochemical properties of 2-methylbenzene-1,3-diamine?

2-methylbenzene-1,3-diamine typically appears as a crystalline solid at room temperature with characteristic aromatic amine properties. The compound contains two primary amino groups (-NH2) attached to a methylated benzene ring, making it polar and capable of hydrogen bonding. Like most aromatic diamines, it is expected to have limited water solubility but good solubility in organic solvents. The presence of amino groups makes it basic in nature and reactive towards electrophiles.

What is 2-methylbenzene-1,3-diamine used for?

2-methylbenzene-1,3-diamine is primarily used as an intermediate in the synthesis of dyes, pigments, and pharmaceutical compounds. Its diamine structure makes it valuable for producing polyamides, epoxy curing agents, and various polymer materials. The compound also serves as a building block in the manufacture of specialty chemicals and can be used in the production of corrosion inhibitors and antioxidants for industrial applications.

How to handle 2-methylbenzene-1,3-diamine safely?

2-methylbenzene-1,3-diamine requires careful handling due to its mutagenic properties and potential for skin sensitization. Essential protective equipment includes nitrile gloves, safety goggles, and appropriate respiratory protection when dust or vapors may be present. Work should be conducted in well-ventilated areas or under fume extraction. Avoid skin and eye contact, and prevent inhalation of dust or vapors. Emergency eyewash and shower facilities should be readily accessible in work areas.

How to store 2-methylbenzene-1,3-diamine correctly?

2-methylbenzene-1,3-diamine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers away from incompatible materials such as strong oxidizing agents, acids, and reactive chemicals. Storage areas should be equipped with appropriate spill containment measures and maintained at controlled temperatures. Ensure proper labeling and restrict access to authorized personnel only.

What to do in case of contact with 2-methylbenzene-1,3-diamine?

In case of skin contact with 2-methylbenzene-1,3-diamine, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms persist or in case of significant exposure.

How to dispose of 2-methylbenzene-1,3-diamine appropriately?

2-methylbenzene-1,3-diamine must be disposed of as hazardous waste through licensed waste management companies in accordance with local and national regulations. The compound cannot be disposed of in regular waste streams due to its mutagenic properties and environmental classification. Collection, transport, and disposal must follow strict protocols for hazardous chemicals. Maintain proper documentation of disposal activities and ensure compliance with REACH and waste framework directive requirements.

How to transport 2-methylbenzene-1,3-diamine?

2-methylbenzene-1,3-diamine is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to international dangerous goods regulations. Packages must display the proper shipping name, UN number, and hazard labels. Transport vehicles need appropriate placarding and drivers must have proper training and certification for handling dangerous goods.

Is 2-methylbenzene-1,3-diamine subject to specific regulations?

2-methylbenzene-1,3-diamine is subject to REACH registration requirements in Europe and must comply with CLP classification and labeling regulations. The compound requires safety data sheets and appropriate hazard communication due to its mutagenic properties (Muta. 2) and skin sensitization potential. While not currently listed as SVHC, it may be subject to restrictions under various chemical safety regulations and requires authorization for certain industrial uses.

Where to buy 2-methylbenzene-1,3-diamine in Europe?

2-methylbenzene-1,3-diamine is available through OYSI, a specialized European distributor of technical chemicals and intermediates. OYSI provides reliable supply chains for industrial customers requiring this aromatic diamine for manufacturing applications. As a professional chemical distributor, OYSI ensures proper handling, documentation, and regulatory compliance for hazardous substances. Contact OYSI directly for availability, technical specifications, and pricing information for your specific requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.