Phenol

C6H6O

phenol

CAS108-95-2
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
108-95-2
EC Number
203-632-7
UN Number
2312
Index Number
604-001-00-8
PubChem CID
996

Physical-chemical properties

Molecular Formula
C6H6O
Molar Mass
94.11 g/mol
IUPAC Name
phenol

Chemical Identifiers

InChI
InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H
InChI Key
ISWSIDIOOBJBQZ-UHFFFAOYSA-N

Overview

Phenol (CAS 108-95-2) is an aromatic organic compound with hydroxyl functionality, characterized by its distinctive odor and corrosive properties. This fundamental aromatic alcohol, also known by its IUPAC name phenol, serves as a crucial building block in numerous industrial processes and chemical syntheses. With the molecular formula C6H6O and a molecular weight of 94.11 g/mol, phenol consists of a benzene ring with a hydroxyl group directly attached, giving it unique chemical reactivity and physical properties. The compound appears as colorless to light pink crystalline solids or liquid, depending on purity and temperature conditions. Phenol presents significant safety considerations due to its classification under multiple hazard categories. The substance carries a "Danger" signal word and displays GHS pictograms GHS08, GHS06, and GHS05, indicating serious health hazards including mutagenic properties (Muta. 2), acute toxicity (Acute Tox. 3), skin corrosion (Skin Corr. 1B), and specific target organ toxicity with repeated exposure (STOT RE 2). Transportation requires adherence to ADR Class 6.1 regulations for toxic substances. Proper handling procedures, including appropriate personal protective equipment and ventilation systems, are essential when working with phenolic compounds. Industrial applications of phenol span multiple sectors, with primary uses including phenolic resin production for adhesives and molding compounds, pharmaceutical intermediate synthesis, and as a precursor in the manufacture of various chemical derivatives. The compound shares chemical families with substances like chloromethylbenzene, both serving important roles in organic synthesis pathways. OYSI maintains reliable supply chains for phenol, ensuring consistent availability to meet diverse industrial requirements across European markets.

Safety & Classification

Danger
Classification:

Muta. 2; Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE 2 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H341

Suspected of causing genetic defects.

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2312
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping NamePhenol, geschmolzen
Marine PollutantNo

Frequently Asked Questions

What is Phenol?

Phenol is an aromatic organic compound with the molecular formula C6H6O and a molecular weight of 94.11 g/mol. It consists of a benzene ring with a hydroxyl group (-OH) attached directly to it. This white crystalline solid is highly toxic and corrosive, classified as a dangerous substance with mutagenic properties. Phenol is widely used in industrial applications but requires careful handling due to its hazardous nature and ability to cause severe chemical burns.

What are the physicochemical properties of Phenol?

Phenol is a white crystalline solid at room temperature with a distinctive sweet, medicinal odor. It has a melting point of 40.5°C and a boiling point of 181.7°C. The compound is moderately soluble in water (about 8.3 g/100 mL at 20°C) and highly soluble in alcohol and ether. Phenol is hygroscopic, meaning it absorbs moisture from air, and can turn pink or red upon exposure to light and air due to oxidation.

What is Phenol used for?

Phenol is primarily used as an intermediate in the production of plastics, particularly phenolic resins and polycarbonates. It serves as a raw material for manufacturing bisphenol A, which is essential for epoxy resins and polycarbonate plastics. Additionally, phenol is used in the production of pharmaceuticals, dyes, explosives, and as a disinfectant in industrial applications. It also finds use in the synthesis of various organic compounds and as a laboratory reagent.

How to handle Phenol safely?

Phenol requires strict safety measures due to its corrosive and toxic nature. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, face shield, and protective clothing covering all skin. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid direct skin contact as phenol can cause severe chemical burns and is readily absorbed through skin. Use appropriate tools for handling and ensure emergency shower and eyewash stations are accessible.

How to store Phenol correctly?

Phenol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Storage temperature should remain below 40°C to prevent melting. Keep away from strong oxidizing agents, alkalis, and reactive metals. Containers must be made of compatible materials such as glass or specific plastics. Storage areas should be equipped with appropriate spill control measures and access should be restricted to trained personnel only.

What to do in case of contact with Phenol?

Phenol contact requires immediate emergency response due to its corrosive nature. For skin contact, immediately remove contaminated clothing and flush affected area with copious amounts of water for at least 15 minutes, then seek medical attention. If phenol contacts eyes, irrigate immediately with water for at least 15 minutes and get medical help. In case of inhalation, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always contact emergency services for significant exposure.

How to dispose of Phenol appropriately?

Phenol disposal must comply with local and international hazardous waste regulations due to its toxic and corrosive properties. It cannot be disposed of with regular waste or poured down drains. Small quantities can be neutralized and incinerated at authorized hazardous waste facilities with appropriate emission controls. Large quantities require collection by licensed hazardous waste disposal companies. Always consult local environmental authorities for specific disposal requirements and maintain proper documentation of waste disposal activities.

How to transport Phenol?

Phenol is classified under ADR regulations as Class 6.1 (Toxic substances) Packing Group II, indicating its high toxicity level. Transportation requires appropriate hazardous goods packaging, labeling with GHS pictograms (GHS05, GHS06, GHS08), and proper shipping documentation. Vehicles must display appropriate hazard placards and drivers need hazardous materials certification. Packages must be secured to prevent spillage and emergency response information must accompany shipments. Only authorized carriers experienced in dangerous goods transport should handle phenol shipments.

Is Phenol subject to specific regulations?

Phenol is subject to extensive regulatory oversight under multiple frameworks including REACH, CLP, and various national regulations. It requires safety data sheets and hazard communication due to its classification as Acute Tox. 3, Skin Corr. 1B, Muta. 2, and STOT RE 2. Although not currently listed as an SVHC (Substance of Very High Concern), its mutagenic properties make it subject to strict handling and reporting requirements. Industrial users must comply with occupational exposure limits and environmental discharge regulations.

Where to buy Phenol in Europe?

Phenol is available through OYSI, a specialized European distributor of industrial chemicals serving the professional market. As a regulated hazardous substance, phenol can only be sold to qualified industrial users who demonstrate appropriate handling capabilities and safety measures. OYSI provides technical support, safety documentation, and ensures compliance with European chemical regulations. Purchase requires proper business credentials and adherence to end-use restrictions. Contact OYSI directly for availability, specifications, and regulatory compliance assistance for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.