2-(chloromethyl)oxirane

2-(chloromethyl)oxirane is an organochlorine compound with the molecular formula C3H5ClO and CAS number 106-89-8. This chemical features both an epoxide ring and a chloromethyl group, making it a highly reactive intermediate. With a molecular weight of 92.52 g/mol, it is classified as a dangerous substance due to its carcinogenic properties, flammability, and corrosive nature. It requires careful handling under controlled conditions due to its multiple hazard classifications.

2-(chloromethyl)oxirane is a colorless liquid at room temperature with a characteristic pungent odor. The compound is moderately soluble in water and miscible with most organic solvents due to its polar chlorine atom and epoxide functionality. It has a relatively low boiling point and high vapor pressure, contributing to its flammable liquid classification. The presence of both electrophilic centers makes it highly reactive toward nucleophiles.

2-(chloromethyl)oxirane serves as a crucial intermediate in organic synthesis and chemical manufacturing. It is primarily used in the production of epoxy resins, pharmaceuticals, and specialty chemicals. The compound acts as an alkylating agent in various synthetic pathways and is employed in the manufacture of glycerol derivatives. Its dual reactive sites make it valuable for creating cross-linked polymer networks and in the synthesis of complex organic molecules.

2-(chloromethyl)oxirane requires strict safety protocols due to its corrosive and carcinogenic nature. Personnel must wear full chemical-resistant suits, nitrile gloves, and respiratory protection with appropriate filters. Work should be conducted in well-ventilated areas or under fume hoods to prevent vapor exposure. Eye protection and emergency shower facilities must be readily available. All handling procedures should minimize skin contact and inhalation risks through proper engineering controls.

2-(chloromethyl)oxirane must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition points. The storage area should be equipped with appropriate fire suppression systems and maintained below 25°C. Keep away from strong bases, acids, and nucleophilic compounds that could trigger unwanted reactions. Secondary containment is recommended, and storage areas should be restricted to authorized personnel only with appropriate hazard signage.

Immediate action is required for any contact with 2-(chloromethyl)oxirane due to its corrosive properties. For skin contact, immediately flush the affected area with copious amounts of water for at least 15 minutes and remove contaminated clothing. In case of eye contact, rinse continuously with water and seek immediate medical attention. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek emergency medical care immediately.

2-(chloromethyl)oxirane disposal must comply with hazardous waste regulations due to its carcinogenic classification. The compound should be collected in appropriate hazardous waste containers and disposed of through licensed hazardous waste treatment facilities. Incineration at high temperatures with appropriate emission controls is typically required. Never dispose of this substance through regular drains or waste streams. Consult local environmental authorities for specific disposal requirements and authorized waste management companies.

2-(chloromethyl)oxirane is classified as UN Class 6.1 (toxic substances) Packing Group II for transportation purposes. It requires appropriate hazardous goods packaging, labeling with GHS pictograms (GHS02, GHS08, GHS06, GHS05), and proper shipping documentation. Transport vehicles must comply with ADR regulations for toxic substances. Only trained personnel should handle the transportation, and emergency response information must accompany shipments. Special routing and timing restrictions may apply in certain jurisdictions.

2-(chloromethyl)oxirane is subject to extensive regulatory oversight due to its Category 1B carcinogenic classification under CLP regulation. It requires registration under REACH for commercial use in Europe. The substance may be subject to authorization requirements and workplace exposure limits. Users must implement appropriate risk management measures and provide safety data sheets. Strict occupational health monitoring and reporting requirements apply to facilities handling this compound for commercial purposes.

2-(chloromethyl)oxirane is available through specialized chemical distributors like OYSI, which serves the European market with technical-grade chemicals. Due to its hazardous nature and regulatory requirements, procurement requires proper documentation, safety qualifications, and compliance with local regulations. OYSI can provide technical support, safety documentation, and appropriate packaging for professional users. Contact OYSI directly to discuss specific requirements, quantities, and regulatory compliance for your application.