2-chloroacetaldehyde

2-chloroacetaldehyde is an organochlorine compound with the molecular formula C2H3ClO and CAS number 107-20-0. This chemical substance has a molecular weight of 78.5 g/mol and belongs to the aldehyde family. It is classified as a highly hazardous substance with multiple danger classifications including carcinogenic properties (Category 2), acute toxicity, skin corrosion, and aquatic toxicity. The compound requires careful handling due to its corrosive and potentially carcinogenic nature.

2-chloroacetaldehyde is a liquid organic compound at room temperature with strong reactive properties typical of aldehydes. As an organochlorine substance, it exhibits high chemical reactivity due to both the aldehyde functional group and the chlorine substituent. The compound is highly corrosive to skin and other materials, as indicated by its Skin Corr. 1B classification. Its low molecular weight (78.5 g/mol) and chemical structure make it volatile and potentially dangerous upon exposure.

2-chloroacetaldehyde serves primarily as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. The compound is utilized in the production of various chemicals where its reactive aldehyde and chlorine functionalities are valuable for further chemical transformations. Due to its high toxicity and carcinogenic classification, its use is restricted to professional industrial applications with appropriate safety measures. It may also be employed in specialized research applications within controlled laboratory environments.

2-chloroacetaldehyde requires extreme caution during handling due to its acute toxicity and corrosive properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, face protection, and appropriate respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Given its carcinogenic classification (Carc. 2) and acute toxicity ratings, only trained personnel should handle this substance following strict safety protocols and emergency procedures.

2-chloroacetaldehyde must be stored in tightly sealed, chemically compatible containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Storage areas should be equipped with appropriate containment measures and emergency equipment. Due to its corrosive nature and high toxicity classification, the substance requires segregation from other chemicals and restricted access. Storage facilities must comply with local regulations for handling carcinogenic and highly toxic substances, including proper labeling and inventory management.

Immediate action is critical due to 2-chloroacetaldehyde's corrosive and toxic properties. For skin contact, immediately remove contaminated clothing and flush the affected area with plenty of water for at least 15 minutes, then seek immediate medical attention. In case of eye contact, rinse immediately with water for at least 15 minutes and seek urgent medical care. If inhaled, move the person to fresh air immediately and seek medical attention. For ingestion, do not induce vomiting and seek immediate emergency medical treatment.

2-chloroacetaldehyde disposal must comply with strict hazardous waste regulations due to its carcinogenic and highly toxic classification. The substance cannot be disposed of through regular waste streams and requires specialized hazardous waste treatment facilities. Disposal must follow local and international environmental regulations, including proper documentation and tracking. Professional waste management companies experienced in handling carcinogenic and corrosive substances should be contracted for safe collection, transport, and destruction using appropriate high-temperature incineration or other approved methods.

2-chloroacetaldehyde is classified under ADR as Class 6.1 (Toxic substances), Packing Group I, indicating its high toxicity level for transport purposes. Transportation requires specialized packaging that meets UN specifications for highly toxic substances and appropriate hazard labeling including GHS pictograms (GHS08, GHS06, GHS05, GHS09). Only certified carriers experienced in handling dangerous goods should transport this substance, following strict documentation requirements and emergency response procedures. Proper shipping papers and emergency contact information must accompany all shipments.

2-chloroacetaldehyde is subject to extensive regulatory oversight due to its hazardous properties. Under EU regulations, it falls under REACH registration requirements and CLP classification with the signal word 'Danger' and multiple hazard classifications. The substance's carcinogenic classification (Carc. 2) subjects it to additional restrictions and workplace exposure limits. While not currently listed as an SVHC, its toxic and corrosive properties require compliance with occupational health regulations, environmental protection laws, and specific handling protocols for carcinogenic substances.

2-chloroacetaldehyde is available through specialized chemical distributors in Europe, including OYSI, which supplies industrial chemicals to European markets. Due to the substance's hazardous classification and regulatory requirements, purchase is typically restricted to qualified industrial users and research institutions with appropriate handling capabilities. Buyers must demonstrate proper safety infrastructure, trained personnel, and compliance with regulatory requirements. OYSI provides technical support and documentation to ensure safe handling and regulatory compliance for professional customers requiring this specialized chemical intermediate.