Ethyl formate

C3H6O2

ethyl formate

CAS109-94-4
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
109-94-4
EC Number
203-721-0
UN Number
1190
Index Number
607-015-00-7
PubChem CID
8025

Physical-chemical properties

Molecular Formula
C3H6O2
Molar Mass
74.08 g/mol
IUPAC Name
ethyl formate

Chemical Identifiers

InChI
InChI=1S/C3H6O2/c1-2-5-3-4/h3H,2H2,1H3
InChI Key
WBJINCZRORDGAQ-UHFFFAOYSA-N

Overview

Ethyl formate (CAS 109-94-4) is an organic ester compound characterized by its high volatility and distinctive fruity odor. This colorless liquid represents one of the simplest formic acid esters, formed through the esterification reaction between formic acid and ethanol. With its molecular formula C3H6O2 and relatively low molecular weight of 74.08 g/mol, ethyl formate exhibits exceptional volatility and rapid evaporation rates at ambient temperatures. The compound belongs to the same chemical family as other volatile organic esters, though it demonstrates distinctly different properties compared to aromatic compounds like ethylbenzene or styrene. Ethyl formate presents significant safety considerations due to its flammable liquid classification (Class 2) and acute toxicity profile. The substance carries a "Danger" signal word with GHS02 and GHS07 pictograms, indicating both fire hazard and health risks including eye irritation and specific target organ toxicity. Its ADR classification as Class 3 material requires specialized handling and transportation protocols. The compound's high vapor pressure necessitates adequate ventilation systems and appropriate personal protective equipment during industrial operations. The primary industrial applications of ethyl formate leverage its excellent solvency properties and rapid evaporation characteristics. It serves as an effective solvent in pharmaceutical manufacturing processes, particularly for extraction and purification operations. The food and fragrance industries utilize ethyl formate as a flavoring agent due to its natural rum-like aroma profile. Additionally, it functions as an intermediate in organic synthesis reactions and as a fumigant in agricultural applications. OYSI maintains reliable supply chains for ethyl formate, ensuring consistent availability for European industrial customers requiring this specialized organic solvent.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Acute Tox. 4 *; Acute Tox. 4 *; STOT SE 3; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H332

Harmful if inhaled.

H302

Harmful if swallowed.

H335

May cause respiratory irritation.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1190
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameEthylformiat
Marine PollutantNo

Frequently Asked Questions

What is ethyl formate?

Ethyl formate is an organic chemical compound with the molecular formula C3H6O2 and CAS number 109-94-4. It belongs to the ester family and has a molecular weight of 74.08 g/mol. This volatile compound is classified as a flammable liquid with moderate toxicity properties. It appears as a colorless liquid with a characteristic fruity odor reminiscent of rum or peach. Ethyl formate is widely used in various industrial applications due to its solvent properties and pleasant aroma.

What are the physicochemical properties of ethyl formate?

Ethyl formate is a colorless, volatile liquid with a pleasant fruity odor similar to rum or peach. It has a molecular weight of 74.08 g/mol and is moderately soluble in water while being miscible with most organic solvents. The compound has a low boiling point of approximately 54°C and a flash point around -20°C, making it highly flammable. It evaporates readily at room temperature and has a density lower than water.

What is ethyl formate used for?

Ethyl formate is primarily used as a solvent in various industrial applications, particularly in the production of coatings, adhesives, and inks. It serves as a flavoring agent in the food industry due to its fruity aroma and as a fragrance component in perfumes and cosmetics. The compound is also utilized in pharmaceutical manufacturing as a reaction medium and in the production of other chemical intermediates. Its fast evaporation rate makes it valuable in quick-drying formulations.

How to handle ethyl formate safely?

Ethyl formate must be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection when necessary. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Eliminate all ignition sources as the compound is highly flammable (Class 2). Avoid contact with skin and eyes due to its irritant properties. Ground all equipment to prevent static electricity buildup during transfer operations.

How to store ethyl formate correctly?

Ethyl formate should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Storage temperature should be kept below 25°C to minimize vapor formation. Keep containers away from incompatible materials such as strong oxidizing agents and strong bases. Store in approved flammable liquid storage cabinets when possible and ensure proper grounding of containers. Regularly inspect containers for leaks or damage.

What to do in case of contact with ethyl formate?

In case of skin contact with ethyl formate, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately and monitor breathing. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms persist.

How to dispose of ethyl formate properly?

Ethyl formate must be disposed of in accordance with local, national, and international hazardous waste regulations. The compound cannot be disposed of in regular waste streams due to its flammable and toxic properties. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities may be allowed for controlled incineration at high temperatures in specialized facilities. Never discharge into sewers, waterways, or soil.

How to transport ethyl formate?

Ethyl formate is classified as ADR Class 3 (Flammable Liquids), Packing Group II for transport purposes. It must be transported in approved packaging that meets UN specifications and properly labeled with appropriate hazard placards. Vehicles must be equipped with appropriate firefighting equipment and drivers must hold valid ADR certification. Transport should avoid extreme temperatures and ensure proper ventilation. Emergency response information must accompany all shipments.

Is ethyl formate subject to specific regulations?

Ethyl formate is subject to various European regulations including REACH registration requirements and CLP classification obligations. It must be labeled with GHS pictograms GHS02 and GHS07, along with the signal word "Danger." The compound is classified as Flam. Liq. 2, Acute Tox. 4, STOT SE 3, and Eye Irrit. 2 under CLP regulation. It is not currently listed as a SVHC substance. Users must comply with workplace safety regulations and provide appropriate safety data sheets.

Where to buy ethyl formate in Europe?

Ethyl formate is available through OYSI, a leading European distributor of technical chemicals serving various industries across Europe. OYSI provides high-quality ethyl formate with comprehensive technical support and regulatory documentation. As a specialized chemical distributor, OYSI ensures compliance with European regulations and provides reliable supply chain solutions. Contact OYSI directly for specific product specifications, quantities, and delivery options tailored to your industrial requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.