Thiolane

Thiolane is a heterocyclic organic compound with the molecular formula C4H8S and CAS number 110-01-0. It is a five-membered ring containing one sulfur atom and four carbon atoms, also known as tetrahydrothiophene. With a molecular weight of 88.17 g/mol, thiolane is classified as a flammable liquid with toxicity and irritation properties, requiring careful handling in industrial applications.

Thiolane is a colorless to pale yellow liquid at room temperature with a characteristic unpleasant, garlic-like odor. It has a boiling point of approximately 121°C and is moderately soluble in water while being miscible with most organic solvents. The compound is volatile and exhibits flammable properties, making it classified as Flammable Liquid Category 2 under GHS classification.

Thiolane serves primarily as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. It is used in the production of various sulfur-containing compounds, as a solvent in specialized applications, and as a building block for synthesizing more complex molecules. The compound also finds applications in research laboratories for chemical analysis and as a reagent in organic chemistry reactions.

Thiolane requires careful handling due to its flammable and toxic nature. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and adequate ventilation or respiratory protection. Work should be conducted away from ignition sources, heat, and open flames. The compound can cause skin and eye irritation, so direct contact must be avoided. Use appropriate fume hoods and ensure proper grounding of equipment.

Thiolane must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use tightly sealed containers made of compatible materials and keep away from oxidizing agents and strong acids. Storage areas should be equipped with appropriate fire suppression systems and spill containment measures. Maintain temperatures below 25°C and ensure containers are properly labeled according to GHS requirements.

Thiolane exposure requires immediate action depending on the contact type. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical care.

Thiolane disposal must comply with local and European waste regulations as it is classified as hazardous waste. The compound should never be poured down drains or disposed of with regular waste. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities can be neutralized through controlled incineration at authorized facilities. Always consult local environmental authorities for specific disposal requirements.

Thiolane is classified under ADR Class 3 (Flammable Liquids), Packing Group II, requiring specialized transport procedures. Packages must bear proper hazard labels including GHS02 and GHS07 pictograms with 'Danger' signal word. Transport vehicles need appropriate placarding and drivers require ADR certification. Containers must meet UN specification standards and be properly secured during transport to prevent spillage or damage.

Thiolane is regulated under European REACH and CLP regulations due to its hazardous properties. It is not currently listed as a Substance of Very High Concern (SVHC). Suppliers must provide Safety Data Sheets and ensure proper classification and labeling. The compound may be subject to workplace exposure limits and requires compliance with occupational health and safety regulations in industrial settings.

Thiolane is available through OYSI, a European distributor specializing in technical chemical products. As an established chemical distributor, OYSI can provide thiolane with proper documentation, safety data sheets, and regulatory compliance support. For pricing, availability, and technical specifications, contact OYSI directly through their European distribution network. They ensure quality products meeting European regulatory standards for industrial applications.