Thiolane

Thiolane is a heterocyclic organic compound with the molecular formula C4H8S and CAS number 110-01-0. This sulfur-containing molecule has a molecular weight of 88.17 g/mol and belongs to the family of thiophenes. It is classified as a flammable liquid with moderate toxicity and irritant properties, requiring careful handling in industrial applications due to its hazardous nature.

Thiolane is a colorless to pale yellow liquid at room temperature with a characteristic sulfur-like odor. As an organic sulfur compound, it has limited solubility in water but is miscible with most organic solvents. The compound exhibits flammable properties and volatility, making it suitable for various chemical reactions while requiring appropriate safety measures during handling and storage.

Thiolane serves primarily as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of various sulfur-containing compounds, as a solvent in specialized chemical reactions, and as a building block for more complex molecules. Its unique ring structure makes it valuable in research applications and custom chemical synthesis processes.

Thiolane requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods due to its flammable nature and potential toxicity. Avoid skin and eye contact, prevent inhalation of vapors, and keep away from ignition sources, heat, and incompatible materials during handling operations.

Thiolane should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition points. Storage areas must be equipped with appropriate fire prevention systems and should be separated from incompatible materials such as strong oxidizers. Containers should be grounded during transfer operations, and storage temperature should be maintained below recommended limits to prevent vapor buildup.

In case of skin contact with thiolane, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush eyes with clean water for 15 minutes while holding eyelids open. If inhaled, move person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention in all exposure cases.

Thiolane disposal must comply with local, national, and EU waste regulations as a hazardous chemical waste. The substance should never be poured down drains or disposed of with regular waste. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities may require neutralization or incineration at specialized facilities equipped to handle flammable and toxic organic compounds.

Thiolane is classified under ADR Class 3 (Flammable Liquids), Packing Group II, requiring specific transport regulations compliance. Packages must bear appropriate hazard labels including GHS02 and GHS07 pictograms with 'Danger' signal word. Vehicles must carry proper documentation, emergency equipment, and drivers need ADR certification. Transport containers must meet UN specification standards for flammable liquids with medium hazard level.

Thiolane is regulated under EU CLP Regulation with classifications including Flammable Liquid Category 2, Acute Toxicity Category 4, and Skin/Eye Irritation Category 2. It falls under REACH registration requirements for chemical substances. The compound is not currently listed as an SVHC (Substance of Very High Concern), but users must comply with safety data sheet requirements and workplace exposure limits where established.

Thiolane is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers across Europe. OYSI provides this compound with full regulatory compliance documentation, proper packaging, and technical support. As a professional chemical distributor, OYSI ensures quality standards and reliable supply chains for laboratory and industrial applications requiring this specialized sulfur compound.