3-chloroprop-1-ene

C3H5Cl

CAS107-05-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
107-05-1
EC Number
203-457-6
UN Number
1100
Index Number
602-029-00-X
PubChem CID
7850

Physical-chemical properties

Molecular Formula
C3H5Cl
Molar Mass
76.52 g/mol
IUPAC Name
3-chloroprop-1-ene

Chemical Identifiers

InChI
InChI=1S/C3H5Cl/c1-2-3-4/h2H,1,3H2
InChI Key
OSDWBNJEKMUWAV-UHFFFAOYSA-N

Overview

3-chloroprop-1-ene (CAS 107-05-1) is an organochlorine compound with high reactivity and significant industrial utility as a chemical intermediate. This unsaturated organochlorine compound, also known by its IUPAC designation 3-chloroprop-1-ene, represents a critical building block in synthetic organic chemistry. With the molecular formula C3H5Cl and a molecular weight of 76.52 g/mol, this colorless liquid exhibits the characteristic properties of both alkenes and alkyl halides, making it exceptionally versatile for chemical transformations. The presence of both a carbon-carbon double bond and a chlorine substituent provides multiple reactive sites for various chemical reactions. The compound presents significant safety considerations due to its classification under multiple hazard categories. It is classified as a flammable liquid (Category 2), suspected carcinogen (Category 2), and suspected mutagen (Category 2), requiring stringent handling protocols and appropriate safety measures. The ADR Class 3 designation reflects its flammable nature, while the GHS pictograms (GHS02, GHS08, GHS07, GHS09) indicate fire, health, acute toxicity, and environmental hazards respectively. In industrial applications, 3-chloroprop-1-ene serves primarily as an intermediate in the synthesis of various chemicals including pharmaceuticals, agrochemicals, and specialty polymers. Its reactivity profile makes it valuable for producing epichlorohydrin and other chlorinated compounds. Unlike simpler hydrocarbons such as propylbenzene, this chlorinated alkene offers enhanced reactivity for nucleophilic substitution and addition reactions. OYSI maintains reliable supply chains for 3-chloroprop-1-ene, ensuring consistent availability for qualified industrial customers across European markets with full regulatory compliance and technical support.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Carc. 2; Muta. 2; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; STOT SE 3; STOT R...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H351

Suspected of causing cancer.

H341

Suspected of causing genetic defects.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H335

May cause respiratory irritation.

H373

May cause damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H400

Very toxic to aquatic life.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1100
ADR Class3
Packing GroupI
Tunnel CodeC/E
Proper Shipping NameAllylchlorid
Marine PollutantNo

Frequently Asked Questions

What is 3-chloroprop-1-ene?

3-chloroprop-1-ene is an organochlorine compound with the molecular formula C3H5Cl and CAS number 107-05-1. This chemical substance has a molecular weight of 76.52 g/mol and belongs to the family of chlorinated alkenes. It is classified as a hazardous substance with multiple danger classifications including flammable liquid, carcinogen, and mutagen. The compound carries the danger signal word and requires strict handling protocols due to its significant health and safety risks.

What are the physicochemical properties of 3-chloroprop-1-ene?

3-chloroprop-1-ene is a colorless liquid at room temperature with a sweet, pungent odor characteristic of chlorinated hydrocarbons. As an alkene derivative, it exhibits typical unsaturated hydrocarbon properties with enhanced reactivity due to the chlorine substituent. The compound has low water solubility but dissolves readily in organic solvents. Its flammable nature and volatility require careful consideration during handling and storage operations in industrial applications.

What is 3-chloroprop-1-ene used for?

3-chloroprop-1-ene is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. It serves as a building block for producing various chlorinated compounds, pharmaceuticals, and specialty chemicals. The compound finds applications in polymer chemistry and as a reagent in research laboratories. Due to its hazardous classification as a carcinogen and mutagen, its industrial use is strictly regulated and limited to professional applications with appropriate safety measures.

How to handle 3-chloroprop-1-ene safely?

3-chloroprop-1-ene requires extensive personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection due to its toxic and carcinogenic properties. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Fire prevention measures are essential given its flammable liquid classification. Only trained personnel should handle this substance, following strict protocols to minimize skin contact and vapor exposure while maintaining emergency procedures readily available.

How to store 3-chloroprop-1-ene correctly?

3-chloroprop-1-ene must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames due to its flammable classification. The compound should be kept in tightly sealed, chemically compatible containers to prevent vapor release and contamination. Storage areas require fire suppression systems and restricted access due to carcinogenic hazards. Incompatible materials such as strong oxidizers and bases must be stored separately to prevent dangerous reactions.

What to do in case of contact with 3-chloroprop-1-ene?

Immediate action is required for any contact with 3-chloroprop-1-ene due to its acute toxicity. For skin contact, remove contaminated clothing and flush affected area with copious amounts of water for at least 15 minutes. In case of eye contact, irrigate immediately with clean water and seek medical attention. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical care. Always consult emergency services for exposure incidents.

How to dispose of 3-chloroprop-1-ene appropriately?

3-chloroprop-1-ene must be disposed of as hazardous waste through licensed waste management companies specializing in carcinogenic and toxic substances. The compound cannot be discharged to sewers, soil, or waterways due to environmental hazards indicated by GHS09 pictogram. Incineration at high temperatures in specialized facilities is typically required for destruction. All disposal activities must comply with local and European waste regulations, including proper documentation and chain of custody procedures for hazardous materials.

How to transport 3-chloroprop-1-ene?

3-chloroprop-1-ene is classified under ADR Class 3 (flammable liquids) Packing Group I, indicating high danger level for transportation. The substance requires specialized packaging, labeling with appropriate hazard pictogrammes (GHS02, GHS08, GHS07, GHS09), and transport documentation. Only certified carriers with proper equipment and training can transport this material. Vehicles must comply with ADR regulations including routing restrictions, emergency equipment, and driver certification for hazardous materials transport throughout Europe.

Is 3-chloroprop-1-ene subject to particular regulations?

3-chloroprop-1-ene is subject to strict regulations under REACH and CLP due to its carcinogenic and mutagenic properties. The substance requires safety data sheets, exposure scenarios, and risk management measures for industrial use. While not currently listed as SVHC, its Carc. 2 and Muta. 2 classifications trigger authorization requirements for certain uses. National restrictions may apply for consumer products, and occupational exposure limits must be strictly observed in workplace environments across European jurisdictions.

Where to buy 3-chloroprop-1-ene in Europe?

3-chloroprop-1-ene is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substances. As a professional chemical supplier, OYSI ensures compliance with European regulations including proper documentation, safety data sheets, and transport arrangements. Due to the substance's hazardous classification, purchases are restricted to qualified industrial users and research institutions with appropriate handling capabilities and regulatory permits for carcinogenic materials.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.