2-methylpropan-2-ol

C4H10O

CAS75-65-0
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
75-65-0
EC Number
200-889-7
UN Number
1120
Index Number
603-005-00-1
PubChem CID
6386

Physical-chemical properties

Molecular Formula
C4H10O
Molar Mass
74.12 g/mol
IUPAC Name
2-methylpropan-2-ol

Chemical Identifiers

InChI
InChI=1S/C4H10O/c1-4(2,3)5/h5H,1-3H3
InChI Key
DKGAVHZHDRPRBM-UHFFFAOYSA-N

Overview

2-methylpropan-2-ol (CAS 75-65-0) is a tertiary alcohol with high volatility and excellent solvent properties for various industrial applications. This branched alcohol, also known by its IUPAC name 2-methylpropan-2-ol, represents a key tertiary alcohol in industrial chemistry with the molecular formula C4H10O and molecular weight of 74.12 g/mol. Its unique tertiary structure, where the hydroxyl group is attached to a carbon atom bonded to three other carbon atoms, confers distinctive chemical and physical properties that differentiate it from primary and secondary alcohols. The substance exhibits significant safety considerations, classified under European regulations with hazard classes including Flammable Liquid Category 2, Acute Toxicity Category 4, Specific Target Organ Toxicity Single Exposure Category 3, and Eye Irritation Category 2. The "Danger" signal word and associated GHS pictograms GHS02 and GHS07 reflect its flammable nature and health hazards. Transportation falls under ADR Class 3, requiring appropriate handling protocols for flammable liquids. Key industrial applications include its use as a solvent in chemical synthesis, particularly in reactions requiring aprotic conditions, and as an intermediate in pharmaceutical manufacturing. The compound serves effectively in extraction processes and as a reaction medium where its tertiary structure provides stability against oxidation. Unlike compounds such as ethylbenzene or styrene which are primarily aromatic solvents, 2-methylpropan-2-ol offers unique advantages in polar aprotic applications. The substance's relatively high volatility and good dissolution properties make it valuable in specialized cleaning applications and as a component in certain formulations requiring rapid evaporation rates. OYSI maintains reliable supply chains for 2-methylpropan-2-ol to support diverse European industrial requirements.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Acute Tox. 4 *; STOT SE 3; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H332

Harmful if inhaled.

H335

May cause respiratory irritation.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1120
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping Nametert-Butanol, technisch
Marine PollutantNo

Frequently Asked Questions

What is 2-methylpropan-2-ol?

2-methylpropan-2-ol is a tertiary alcohol commonly known as tert-butanol or t-butyl alcohol. This organic compound has the molecular formula C4H10O and a molecular weight of 74.12 g/mol. It belongs to the alcohol family and is characterized by its branched structure with a hydroxyl group attached to a tertiary carbon atom. The substance is classified as a flammable liquid and poses certain health hazards including acute toxicity and eye irritation.

What are the physicochemical properties of 2-methylpropan-2-ol?

2-methylpropan-2-ol is a colorless liquid at room temperature with a characteristic alcohol-like odor. It has a melting point of approximately 25°C and a boiling point of 82-83°C. The substance is miscible with water and most organic solvents due to its polar hydroxyl group and organic structure. It has a density of about 0.79 g/cm³ and exhibits relatively low volatility compared to other alcohols of similar molecular weight.

What is 2-methylpropan-2-ol used for?

2-methylpropan-2-ol serves as an important industrial solvent and chemical intermediate. It is widely used in the production of methyl methacrylate, a precursor to acrylic plastics and resins. The substance also functions as a solvent in chemical reactions, particularly in pharmaceutical synthesis and laboratory applications. Additionally, it is employed in the manufacture of flavoring agents, perfumes, and as a denaturant for ethanol in various industrial processes.

How to handle 2-methylpropan-2-ol safely?

2-methylpropan-2-ol requires careful handling due to its flammable nature and potential health hazards. Always wear appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Ensure adequate ventilation to prevent vapor accumulation and avoid ignition sources such as open flames, sparks, and hot surfaces. Use grounding and bonding procedures during transfer operations. Avoid direct skin contact and inhalation of vapors to prevent acute toxic effects and eye irritation.

How to store 2-methylpropan-2-ol correctly?

2-methylpropan-2-ol must be stored in a cool, dry, well-ventilated area away from heat sources, ignition sources, and direct sunlight. Use appropriate containers made of compatible materials and ensure they are tightly sealed to prevent vapor release. Store separately from oxidizing agents, strong acids, and incompatible materials. Maintain storage temperatures below the substance's flash point and implement proper fire prevention measures including appropriate fire suppression systems in storage areas.

What to do in case of contact with 2-methylpropan-2-ol?

In case of skin contact with 2-methylpropan-2-ol, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and monitor breathing. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms persist.

How to dispose of 2-methylpropan-2-ol appropriately?

2-methylpropan-2-ol must be disposed of in accordance with local, national, and international waste regulations. The substance should be treated as hazardous waste due to its flammable properties and potential environmental impact. Contact licensed waste disposal companies for proper collection and treatment. Do not discharge into sewers, waterways, or soil. Consider recovery and recycling options where feasible. Always consult current waste classification codes and disposal requirements in your jurisdiction before disposal.

How to transport 2-methylpropan-2-ol?

2-methylpropan-2-ol is classified under ADR Class 3 (Flammable Liquids), Packing Group II, indicating moderate danger during transport. The substance must be packaged in UN-approved containers and properly labeled with appropriate hazard placards and markings. Transport vehicles must comply with ADR requirements including proper ventilation, fire extinguishing equipment, and driver certification. Ensure proper documentation including transport documents and emergency response information accompanies shipments throughout the European transport network.

Is 2-methylpropan-2-ol subject to particular regulations?

2-methylpropan-2-ol is subject to various European chemical regulations including REACH registration requirements and CLP classification standards. The substance is classified with hazard classes including Flammable Liquid Category 2, Acute Toxicity Category 4, and Eye Irritation Category 2. It is not currently listed as a Substance of Very High Concern (SVHC). Compliance with workplace exposure limits, safety data sheet requirements, and proper labeling with GHS02 and GHS07 pictograms is mandatory.

Where to buy 2-methylpropan-2-ol in Europe?

2-methylpropan-2-ol is available through OYSI, a trusted European distributor of industrial chemicals. OYSI provides high-quality 2-methylpropan-2-ol with complete regulatory documentation including safety data sheets and certificates of analysis. As a specialized chemical distributor, OYSI ensures compliance with European regulations and offers reliable supply chain solutions across Europe. Contact OYSI directly for pricing, availability, packaging options, and technical support for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.