2-ethyloxirane

C4H8O

CAS106-88-7
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
106-88-7
EC Number
203-438-2
UN Number
3022
Index Number
603-102-00-9
PubChem CID
7834

Physical-chemical properties

Molecular Formula
C4H8O
Molar Mass
72.11 g/mol
IUPAC Name
2-ethyloxirane

Chemical Identifiers

InChI
InChI=1S/C4H8O/c1-2-4-3-5-4/h4H,2-3H2,1H3
InChI Key
RBACIKXCRWGCBB-UHFFFAOYSA-N

Overview

2-ethyloxirane (CAS 106-88-7) is an epoxide compound with high reactivity and industrial polymerization applications. This organic chemical, also known by its IUPAC designation 2-ethyloxirane, belongs to the epoxide family characterized by a three-membered cyclic ether structure. With the molecular formula C4H8O and a molecular weight of 72.11 g/mol, this colorless liquid exhibits the typical ring strain that makes epoxides highly reactive intermediates in chemical synthesis. The compound shares structural similarities with other industrial chemicals like ethylbenzene and styrene, though its epoxide functionality provides distinct reactivity patterns. The substance requires careful handling due to its significant hazard profile, classified under multiple danger categories including flammable liquid (Category 2), suspected carcinogen (Category 2), and acute toxicity (Category 4). The GHS pictograms GHS02, GHS08, and GHS07 indicate fire hazard, health hazard, and harmful properties respectively. As a Class 3 dangerous good under ADR regulations, it demands specialized transportation and storage protocols. The epoxide ring makes it particularly reactive toward nucleophiles, contributing to both its utility and its toxicological concerns including skin irritation and potential respiratory effects. Primary industrial applications include its use as a chemical intermediate in polymer synthesis, where the reactive epoxide group enables ring-opening polymerization reactions. It serves as a building block for specialty chemicals and can function as an alkylating agent in organic synthesis. The compound also finds application in the production of surfactants and as a reactive diluent in epoxy formulations. OYSI provides 2-ethyloxirane to qualified industrial customers with appropriate technical documentation and safety data sheets to ensure compliant handling and application.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Carc. 2; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; STOT SE 3; Skin Irrit. 2; ...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H351

Suspected of causing cancer.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3022
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name1,2-Butylenoxid, stabilisiert
Marine PollutantNo

Frequently Asked Questions

What is 2-ethyloxirane?

2-ethyloxirane is an organic chemical compound with the molecular formula C4H8O and a molecular weight of 72.11 g/mol. It belongs to the epoxide family, characterized by a three-membered ring containing an oxygen atom. This colorless liquid is classified as a hazardous substance due to its flammable, carcinogenic, and toxic properties. It carries the CAS number 106-88-7 and requires careful handling in industrial applications.

What are the physicochemical properties of 2-ethyloxirane?

2-ethyloxirane is a colorless liquid with a molecular weight of 72.11 g/mol and the formula C4H8O. As an epoxide, it features a highly reactive three-membered ring structure containing oxygen. The compound is flammable and volatile, requiring storage under controlled conditions. Its reactive epoxide group makes it prone to ring-opening reactions, particularly in the presence of nucleophiles or under acidic or basic conditions.

What is 2-ethyloxirane used for?

2-ethyloxirane is primarily used as a chemical intermediate in organic synthesis and industrial manufacturing processes. Its reactive epoxide functionality makes it valuable for producing various chemicals through ring-opening reactions. The compound serves as a building block in the synthesis of specialty chemicals, polymers, and pharmaceutical intermediates. Due to its hazardous classification, its use is typically restricted to professional industrial applications with appropriate safety measures.

How to handle 2-ethyloxirane safely?

2-ethyloxirane requires strict safety protocols due to its flammable, carcinogenic, and toxic properties. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Eliminate ignition sources as the substance is classified as Flam. Liq. 2. Regular health monitoring is recommended due to its carcinogenic classification (Carc. 2).

How to store 2-ethyloxirane correctly?

2-ethyloxirane must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition points. Due to its flammable classification (Class 3, Group II), storage areas should comply with fire prevention regulations. Keep containers upright and protected from physical damage. Store separately from incompatible materials such as strong acids, bases, and oxidizing agents to prevent dangerous reactions.

What to do in case of contact with 2-ethyloxirane?

2-ethyloxirane exposure requires immediate action due to its toxic and irritating properties. For skin contact, immediately remove contaminated clothing and rinse affected areas with plenty of water for at least 15 minutes. In case of eye contact, flush thoroughly with water and seek medical attention. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical care. Always consult a physician after any exposure.

How to dispose of 2-ethyloxirane appropriately?

2-ethyloxirane disposal must comply with local and national hazardous waste regulations due to its toxic and carcinogenic properties. The substance cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities should be neutralized or incinerated at authorized facilities equipped to handle toxic and flammable materials while preventing environmental contamination.

How to transport 2-ethyloxirane?

2-ethyloxirane is classified under ADR Class 3 (flammable liquids), Packing Group II, requiring compliance with dangerous goods transportation regulations. Packages must bear appropriate hazard labels (GHS02, GHS07, GHS08) and the 'Danger' signal word. Transportation vehicles need proper ventilation and fire prevention equipment. Drivers require ADR certification and emergency response information. Packaging must meet UN specifications for Class 3 substances and prevent leakage during transport.

Is 2-ethyloxirane subject to specific regulations?

2-ethyloxirane is subject to extensive European chemical regulations including REACH registration requirements and CLP classification obligations. Its carcinogenic classification (Carc. 2) triggers specific occupational exposure limits and health surveillance requirements. The substance requires safety data sheets and hazard communication under CLP. While not currently listed as an SVHC, its hazardous properties mandate compliance with industrial emission directives and workplace safety regulations across EU member states.

Where to buy 2-ethyloxirane in Europe?

2-ethyloxirane is available through OYSI, a European distributor specializing in technical chemicals for industrial applications. As a hazardous substance requiring professional handling, it is typically supplied only to qualified industrial users with appropriate safety infrastructure. OYSI ensures full regulatory compliance including proper documentation, safety data sheets, and transportation according to ADR requirements. Contact OYSI directly to discuss specific requirements and availability for your industrial application.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.