4-methylaniline
C7H9N
Consulting for 4-methylaniline
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Identification
- CAS Number
- 106-49-0
- EC Number
- 203-403-1
- UN Number
- 3451
- Index Number
- 612-160-00-4
- PubChem CID
- 7813
Physical-chemical properties
- Molecular Formula
- C7H9N
- Molar Mass
- 107.15 g/mol
- IUPAC Name
- 4-methylaniline
Chemical Identifiers
- InChI
- InChI=1S/C7H9N/c1-6-2-4-7(8)5-3-6/h2-5H,8H2,1H3
- InChI Key
- RZXMPPFPUUCRFN-UHFFFAOYSA-N
Overview
4-methylaniline (CAS 106-49-0) is an aromatic amine compound featuring a methyl group substitution on the benzene ring, commonly used as an intermediate in organic synthesis and dye manufacturing. This organic compound, also known by its IUPAC name 4-methylaniline, represents an important building block in industrial chemistry with the molecular formula C7H9N and a molecular weight of 107.15 g/mol. As a substituted aniline derivative, it belongs to the aromatic amine family and exhibits characteristic properties that make it valuable for various synthetic applications. The compound features a para-positioned methyl group on the aniline structure, which influences its reactivity and chemical behavior compared to unsubstituted aniline. 4-methylaniline typically appears as a crystalline solid with distinctive chemical properties inherent to aromatic amines. While specific hazard classifications may vary by jurisdiction, the compound is classified under ADR transport class 6.1, indicating its toxic properties require careful handling protocols. Industrial users should implement appropriate safety measures including proper ventilation, personal protective equipment, and adherence to established handling procedures when working with this material. The primary industrial applications of 4-methylaniline include its use as an intermediate in the synthesis of dyes, pigments, and pharmaceutical compounds. It serves as a crucial starting material for producing various colorants and serves in the manufacture of specialty chemicals. The compound's reactivity profile makes it particularly useful in organic synthesis processes where selective substitution reactions are required. Unlike related compounds such as 4-nitroaniline, which requires reduction steps in many applications, 4-methylaniline offers direct utility in nucleophilic substitution reactions. OYSI provides 4-methylaniline to support diverse industrial applications across Europe, ensuring reliable supply chains for customers in the chemical manufacturing sector.
Safety & Classification
No Hazard Classification
This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.
Transport (ADR)
| UN Number | 3451 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | p-Toluidin, fest |
| Marine Pollutant | No |
Frequently Asked Questions
What is 4-methylaniline?
4-methylaniline is an aromatic amine compound with the chemical formula C7H9N and CAS number 106-49-0. This organic chemical consists of an aniline molecule with a methyl group attached to the para position of the benzene ring. With a molecular weight of 107.15 g/mol, 4-methylaniline serves as an important intermediate in chemical synthesis and manufacturing processes.
What are the physicochemical properties of 4-methylaniline?
4-methylaniline is a crystalline solid at room temperature with a characteristic amine odor. The compound appears as white to pale yellow crystals and has moderate solubility in water while being readily soluble in organic solvents like ethanol and ether. Its melting point is approximately 44-45°C, and it exhibits typical aromatic amine properties including basicity and reactivity.
What is 4-methylaniline used for?
4-methylaniline serves primarily as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. The compound is extensively used in the production of azo dyes, particularly those requiring para-substituted aniline derivatives. Additionally, it finds applications in the manufacture of antioxidants, rubber chemicals, and as a building block for various organic synthesis reactions in the chemical industry.
How to handle 4-methylaniline safely?
4-methylaniline requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin contact and ingestion, as aromatic amines can be absorbed through the skin. Ensure emergency eyewash stations and safety showers are readily accessible.
How to store 4-methylaniline correctly?
4-methylaniline should be stored in tightly closed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep the substance away from strong oxidizing agents, acids, and incompatible materials. Storage areas should be equipped with appropriate spill containment measures and maintained at temperatures below 25°C to prevent degradation and ensure product stability.
What to do in case of contact with 4-methylaniline?
Skin contact with 4-methylaniline requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air and seek medical attention. For ingestion, do not induce vomiting and seek immediate medical care.
How to dispose of 4-methylaniline properly?
4-methylaniline disposal must comply with local environmental regulations and waste management guidelines. The substance should not be discharged into drains, sewers, or the environment. Arrange for disposal through licensed hazardous waste contractors who can handle aromatic amine compounds appropriately. Consider recovery or recycling options where feasible before disposal, and maintain proper waste documentation as required by regulations.
How to transport 4-methylaniline?
4-methylaniline is classified under ADR Class 6.1 (toxic substances) Packing Group II for transportation. The substance requires appropriate hazardous goods packaging, labeling, and documentation when shipped. Transport vehicles must comply with ADR regulations for toxic substances, including proper placarding and driver certification. Ensure shipping containers are properly sealed and labeled with the correct UN identification numbers.
Is 4-methylaniline subject to specific regulations?
4-methylaniline is regulated under various chemical safety frameworks including REACH registration requirements in the European Union. The substance must comply with CLP regulation for classification, labeling, and packaging. It is not currently listed as a Substance of Very High Concern (SVHC), but users must still follow standard chemical safety protocols and maintain appropriate safety data sheets for workplace safety compliance.
Where to buy 4-methylaniline in Europe?
4-methylaniline is available through OYSI, a specialized European distributor of chemical products. OYSI provides reliable supply chains across Europe with proper documentation, quality assurance, and regulatory compliance. As an established chemical distributor, OYSI ensures that all products meet European standards and provides technical support for customers requiring 4-methylaniline for their industrial applications and research needs.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.