4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline

4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline is an aromatic amine compound with the molecular formula C13H12Cl2N2 and CAS number 101-14-4. This chemical features two chlorinated aniline groups connected by a methyl bridge, resulting in a molecular weight of 267.15 g/mol. It is classified as a Category 1B carcinogen and poses significant health and environmental hazards, requiring careful handling in industrial applications.

4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline is typically a solid crystalline compound at room temperature with a molecular weight of 267.15 g/mol. As an aromatic amine with chlorine substituents, it generally exhibits limited water solubility but good solubility in organic solvents. The compound's physicochemical behavior is influenced by the presence of amino groups and chlorine atoms, affecting its reactivity and environmental persistence.

4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline is primarily used as an intermediate in the synthesis of dyes, pigments, and other organic compounds. This aromatic amine serves as a building block in chemical manufacturing processes, particularly in the production of azo dyes and specialized chemical intermediates. Its dual amine functionality makes it valuable for creating complex molecular structures in pharmaceutical and chemical research applications.

4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline requires strict safety protocols due to its carcinogenic properties and acute toxicity. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Skin and eye contact must be avoided completely, and all handling procedures should follow established safety guidelines for carcinogenic substances.

4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. The compound must be kept in tightly sealed containers to prevent contamination and exposure. Storage areas should be secured and restricted to authorized personnel only, given its carcinogenic classification. Regular inspection of storage conditions and container integrity is essential to maintain safety standards.

Immediate action is required upon contact with 4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly in all exposure cases, informing healthcare providers of the carcinogenic nature of the substance.

4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline must be disposed of as hazardous waste through licensed waste management companies. Due to its carcinogenic properties and environmental toxicity, incineration at high temperatures in specialized facilities is typically required. Disposal must comply with local and European waste regulations, including proper labeling, documentation, and chain of custody procedures. Never dispose of this substance through regular waste streams or sewage systems.

4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. Proper UN-specification packaging is required, along with appropriate hazard labels and documentation. Transport must comply with ADR regulations for dangerous goods, including driver training requirements and emergency response procedures. Vehicles must carry appropriate safety equipment and emergency contact information during transport.

4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline is subject to extensive European chemical regulations including REACH registration requirements and CLP classification obligations. As a Category 1B carcinogen, it faces strict workplace exposure limits and may be subject to authorization requirements under REACH. Companies handling this substance must maintain safety data sheets, conduct risk assessments, and implement appropriate risk management measures according to European chemical safety legislation.

4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to qualified industrial customers with proper handling capabilities and regulatory compliance. Due to its hazardous classification, purchase requires demonstration of appropriate safety measures and legitimate industrial use. Contact OYSI directly for availability, specifications, and regulatory documentation required for procurement in European markets.