1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine

1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine is a synthetic organic compound with CAS number 210880-92-5 and molecular formula C6H8ClN5O2S. This nitroguanidine derivative contains a thiazole ring system with a chlorine substituent and has a molecular weight of 249.68 g/mol. It is classified as a hazardous substance with reproductive toxicity, acute toxicity, and environmental hazard properties according to CLP regulation.

1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine is a solid compound at room temperature with a molecular weight of 249.68 g/mol. The compound contains multiple polar functional groups including nitro and guanidine moieties, which typically confer moderate to high polarity. The presence of the chlorinated thiazole ring system contributes to its chemical stability. Specific physical properties such as melting point, solubility, and appearance may vary depending on purity and crystalline form.

1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine is primarily used as an active ingredient in insecticide formulations, particularly as a neonicotinoid pesticide. This compound acts on the nervous system of insects by targeting nicotinic acetylcholine receptors. It is employed in agricultural applications for crop protection and pest control. Due to its classification as a reproductive toxicant and environmental hazard, its use is strictly regulated and limited to professional applications with appropriate safety measures.

Safe handling requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume extraction systems to avoid inhalation. Due to its reproductive toxicity classification (Repr. 2), pregnant women and those planning pregnancy should avoid exposure. All handling procedures must follow the safety data sheet recommendations and be performed by trained personnel only.

Storage should be in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and incompatible materials. The compound must be kept in tightly sealed original containers to prevent moisture absorption and contamination. Storage areas should be secure and accessible only to authorized personnel due to the substance's hazardous properties. Containers should be properly labeled and stored according to local chemical storage regulations, maintaining appropriate segregation from other chemicals.

Immediate action involves removing contaminated clothing and flushing affected skin areas with plenty of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek medical attention immediately. If inhaled, move to fresh air and seek medical advice if respiratory symptoms occur. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet and contact emergency services if serious exposure occurs.

Disposal must be conducted through licensed hazardous waste disposal companies in accordance with local and national regulations. The compound cannot be disposed of in regular waste streams due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1). Empty containers should also be treated as hazardous waste. Incineration at authorized high-temperature facilities or other approved treatment methods may be required. Always consult local environmental authorities for specific disposal requirements.

Transportation is regulated under ADR Class 9 (Miscellaneous dangerous goods), Packing Group III, indicating moderate danger during transport. Packages must be properly labeled with appropriate hazard markings and documentation must accompany shipments. Only authorized carriers with dangerous goods certification can handle transportation. Proper packaging specifications must be followed to prevent leakage or spillage during transit. Emergency response information should be readily available during transport.

Yes, this compound is subject to REACH regulation requiring registration for import/manufacture in the EU. It falls under CLP classification with hazard pictogrammes GHS07, GHS08, and GHS09, requiring appropriate labeling and safety data sheets. The substance is not currently listed as a SVHC (Substance of Very High Concern). Pesticide regulations may apply for its use in plant protection products, requiring specific authorizations and compliance with maximum residue limits.

OYSI is a European distributor of chemical products that can supply 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine to qualified industrial customers. As a specialized chemical distributor, OYSI provides proper documentation, safety data sheets, and regulatory compliance support. Due to the hazardous nature of this substance, sales are typically restricted to professional users with appropriate handling capabilities and regulatory permissions. Contact OYSI directly for availability, specifications, and regulatory requirements.