1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine

1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine is a synthetic organic compound with the molecular formula C6H8ClN5O2S and CAS number 210880-92-5. This nitroguanidine derivative contains a thiazole ring system with a chlorine substituent, giving it a molecular weight of 249.68 g/mol. The compound is classified as hazardous with reproductive toxicity concerns, acute toxicity, and environmental hazards, requiring careful handling in professional settings.

1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine is a solid compound at room temperature with a molecular weight of 249.68 g/mol. The presence of the nitroguanidine group and thiazole ring system suggests limited water solubility but potential solubility in organic solvents. The compound's physical appearance, exact melting point, and specific solubility parameters require consultation of detailed technical specifications from the supplier for precise handling requirements.

1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine is primarily used as an intermediate in pharmaceutical synthesis and agrochemical research applications. The compound's nitroguanidine structure and thiazole ring make it valuable for developing bioactive molecules and conducting chemical research. Its specific applications depend on the end-user's requirements, typically involving controlled synthesis processes in laboratory or industrial settings where specialized chemical intermediates are needed.

Safe handling of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine requires full personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work must be conducted in well-ventilated areas or under fume extraction due to its acute toxicity classification. Avoid skin contact and inhalation, as the compound poses reproductive toxicity risks (Repr. 2) and specific target organ toxicity. Always follow the safety data sheet guidelines and ensure proper training before handling.

1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed and properly labeled according to GHS requirements with appropriate pictograms (GHS07, GHS08, GHS09). Storage areas must be restricted to authorized personnel only, given the compound's reproductive toxicity and environmental hazards. Ensure compliance with local regulations for hazardous substance storage and maintain appropriate spill containment measures.

Immediate action for contact with 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine includes removing contaminated clothing and rinsing affected skin or eyes with plenty of water for at least 15 minutes. If inhaled, move the person to fresh air immediately. Seek medical attention promptly, especially considering the compound's acute toxicity and reproductive hazard classification. Do not induce vomiting if swallowed. Always consult the safety data sheet for specific first aid measures and contact emergency services if symptoms develop.

Disposal of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine must be conducted through licensed hazardous waste disposal facilities due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1). The compound cannot be disposed of via regular waste streams or sewage systems. Contact authorized waste management companies specializing in hazardous chemical disposal and follow local environmental regulations. Maintain proper documentation of disposal activities and ensure containers are properly labeled before collection.

Transportation of 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine falls under ADR Class 9 (Miscellaneous dangerous goods), Packing Group III. Proper shipping documentation, hazard labels, and approved packaging materials are required for road transport. The compound must be packaged according to ADR regulations with appropriate marking and placarding. Only qualified carriers with dangerous goods certification should handle transportation, ensuring compliance with international transport regulations for hazardous materials.

1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine is subject to REACH regulation requiring registration for import/manufacture above threshold quantities in the EU. The compound must comply with CLP classification and labeling requirements, displaying appropriate GHS pictograms and hazard statements. While not currently listed as an SVHC, its reproductive toxicity classification may trigger additional reporting requirements. Users must ensure compliance with workplace exposure limits and environmental discharge restrictions due to its aquatic toxicity classification.

1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides comprehensive documentation including certificates of analysis, safety data sheets, and regulatory compliance information. As a specialized chemical intermediate, availability may require advance ordering and minimum quantity requirements. Contact OYSI directly for current pricing, specifications, and delivery schedules to European locations while ensuring proper handling authorization and regulatory compliance.