4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline

C15H18N2

CAS838-88-0
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
838-88-0
EC Number
212-658-8
UN Number
3077
Index Number
612-085-00-7
PubChem CID
13283

Physical-chemical properties

Molecular Formula
C15H18N2
Molar Mass
226.32 g/mol
IUPAC Name
4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline

Chemical Identifiers

InChI
InChI=1S/C15H18N2/c1-10-7-12(3-5-14(10)16)9-13-4-6-15(17)11(2)8-13/h3-8H,9,16-17H2,1-2H3
InChI Key
WECDUOXQLAIPQW-UHFFFAOYSA-N

Overview

4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline (CAS 838-88-0) is an aromatic diamine compound characterized by its dual aniline functionality and methylene bridge structure. This organic chemical belongs to the family of diphenylmethane diamines, featuring two amino-substituted benzene rings connected through a methylene linkage. With the molecular formula C15H18N2 and a molecular weight of 226.32 g/mol, this compound exhibits the typical reactivity patterns associated with aromatic amines while presenting significant safety considerations due to its classification profile. The substance carries serious health and environmental hazard classifications, including carcinogenic properties (Carc. 1B), acute toxicity (Acute Tox. 4), and skin sensitization potential (Skin Sens. 1). Additionally, it poses environmental risks with both acute and chronic aquatic toxicity classifications. These hazard profiles necessitate strict handling protocols and appropriate personal protective equipment during industrial operations. In industrial applications, 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline serves primarily as an intermediate in polymer synthesis, particularly in the production of specialized polyurethanes and epoxy resins. The compound's dual amine functionality makes it valuable for cross-linking applications in advanced materials manufacturing. It also finds use in the synthesis of high-performance dyes and pigments where its aromatic structure contributes to color stability and intensity. This chemical shares structural similarities with related compounds such as 4-(4-amino-3-chlorophenyl)-2-chloroaniline, which belongs to the same diphenylmethane diamine family but features chlorine substitution instead of methyl groups, resulting in different reactivity profiles and applications. OYSI provides reliable access to 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline for qualified industrial customers across European markets, ensuring compliance with regional chemical regulations and safety standards.

Safety & Classification

Danger
Classification:

Carc. 1B; Acute Tox. 4 *; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H302

Harmful if swallowed.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameBis[4,4'-(3-Methylbenzenamin)]methan
Marine PollutantNo

Frequently Asked Questions

What is 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline?

4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline is an aromatic diamine compound with the molecular formula C15H18N2 and CAS number 838-88-0. This chemical features two amino groups attached to methylated phenyl rings connected by a methylene bridge. With a molecular weight of 226.32 g/mol, it is classified as a Category 1B carcinogen and presents significant health and environmental hazards requiring careful handling and specialized safety measures.

What are the physicochemical properties of 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline?

4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline is a solid organic compound at room temperature with a molecular weight of 226.32 g/mol. As an aromatic diamine, it typically appears as a crystalline solid that may darken upon exposure to air and light. The compound contains amino groups that make it reactive and potentially soluble in polar solvents. Its aromatic structure provides stability while the amino functionalities contribute to its chemical reactivity.

What is 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline used for?

4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline is primarily used as an intermediate in chemical synthesis and manufacturing processes. Its diamine structure makes it valuable for producing polymers, dyes, and other specialty chemicals. The compound serves as a building block in organic synthesis where aromatic diamines are required. However, due to its carcinogenic classification, its applications are strictly regulated and limited to controlled industrial processes with appropriate safety measures.

How to handle 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline safely?

4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline requires strict safety protocols due to its carcinogenic and toxic properties. Essential protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas or fume hoods. Avoid skin contact and inhalation completely. Work in designated areas with proper containment systems. Personnel must receive specialized training on carcinogen handling procedures. Emergency shower and eyewash stations should be readily accessible during handling operations.

How to store 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline correctly?

4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline must be stored in tightly sealed containers in cool, dry, well-ventilated areas away from heat sources and direct sunlight. Storage areas should be restricted and clearly marked as containing carcinogenic materials. Keep away from oxidizing agents and incompatible materials. Containers should be properly labeled and stored in secondary containment systems. Regular inspection for container integrity and proper segregation from other chemicals is essential for safe storage.

What to do in case of contact with 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline?

Immediate action is required for any contact with 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline due to its toxicity. For skin contact, immediately remove contaminated clothing and flush affected areas with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, rinse thoroughly with water. Seek immediate medical attention in all cases, informing healthcare providers of the carcinogenic nature of the substance. Do not induce vomiting if ingested.

How to dispose of 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline properly?

4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline must be disposed of as hazardous waste through licensed waste management companies specializing in carcinogenic materials. Incineration at high temperatures in authorized facilities is typically required. Never dispose of in regular waste streams, sewers, or the environment due to its aquatic toxicity classification. All disposal must comply with local, national, and EU waste regulations. Maintain detailed records of all disposal activities for regulatory compliance purposes.

How to transport 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline?

4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transport purposes. Packaging must meet UN specification requirements with proper marking and labeling including GHS pictograms (GHS07, GHS08, GHS09). Transport documents must include the correct shipping name and hazard classifications. Vehicles require appropriate placarding and drivers need ADR certification. Special precautions apply due to the carcinogenic nature of the material.

Is 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline subject to special regulations?

4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline is subject to extensive regulations under EU CLP Regulation due to its Carcinogen Category 1B classification and environmental hazards. REACH registration requirements apply for importers and manufacturers. Occupational exposure limits and workplace health surveillance may be mandatory. The compound requires hazard communication through safety data sheets and appropriate labeling. National carcinogen regulations may impose additional restrictions on use, handling, and worker protection measures.

Where to buy 4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline in Europe?

4-[(4-amino-3-methylphenyl)methyl]-2-methylaniline is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous materials. As a carcinogenic substance, purchase is typically restricted to qualified industrial users with appropriate handling capabilities and regulatory compliance. OYSI provides comprehensive documentation including safety data sheets and certificates of analysis. Customers must demonstrate proper storage facilities, trained personnel, and waste disposal arrangements before purchase approval.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.