2,4-dichloro-1-(4-nitrophenoxy)benzene
C12H7Cl2NO3
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Identification
- CAS Number
- 1836-75-5
- EC Number
- 217-406-0
- UN Number
- 3077
- Index Number
- 609-040-00-9
- PubChem CID
- 15787
Physical-chemical properties
- Molecular Formula
- C12H7Cl2NO3
- Molar Mass
- 284.09 g/mol
- IUPAC Name
- 2,4-dichloro-1-(4-nitrophenoxy)benzene
Chemical Identifiers
- InChI
- InChI=1S/C12H7Cl2NO3/c13-8-1-6-12(11(14)7-8)18-10-4-2-9(3-5-10)15(16)17/h1-7H
- InChI Key
- XITQUSLLOSKDTB-UHFFFAOYSA-N
Overview
2,4-dichloro-1-(4-nitrophenoxy)benzene (CAS 1836-75-5) is an organochlorine compound with significant industrial applications and notable hazard classifications. This chemical substance, also known by its EC number 217-406-0, represents a specialized aromatic ether featuring both chlorine and nitro functional groups. With a molecular formula of C12H7Cl2NO3 and molecular weight of 284.09 g/mol, this compound exhibits the characteristic properties of halogenated aromatic compounds combined with nitro group reactivity. The presence of two chlorine atoms on the benzene ring and a nitrophenoxy substituent contributes to its unique chemical behavior and industrial utility. The compound carries serious safety classifications including carcinogenic (Carc. 1B) and reproductive toxicity (Repr. 1B) properties, requiring careful handling protocols. Its acute toxicity classification (Acute Tox. 4) and environmental hazard ratings (Aquatic Acute 1; Aquatic Chronic 1) necessitate appropriate containment and disposal procedures. The GHS pictograms GHS08, GHS07, and GHS09 reflect these health and environmental concerns, while the ADR Class 9 classification governs its transportation requirements. Industrial applications typically include use as an intermediate in pharmaceutical synthesis, specialty chemical manufacturing, and research applications where its unique aromatic ether structure provides specific reactivity patterns. The compound shares chemical relationship characteristics with other chlorinated aromatic compounds such as 4-[(4-amino-3-chlorophenyl)methyl]-2-chloroaniline, which similarly features chlorinated aromatic systems used in industrial synthesis. Due to its hazardous nature, this substance requires specialized handling expertise and regulatory compliance throughout the supply chain. OYSI provides this technical-grade chemical to qualified industrial customers with comprehensive safety documentation and regulatory support.
Safety & Classification
Carc. 1B; Repr. 1B; Acute Tox. 4 *; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | Nitrofen (ISO) |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2,4-dichloro-1-(4-nitrophenoxy)benzene?
2,4-dichloro-1-(4-nitrophenoxy)benzene is an organic chemical compound with the molecular formula C12H7Cl2NO3 and CAS number 1836-75-5. This substance has a molecular weight of 284.09 g/mol and belongs to the class of chlorinated aromatic compounds containing both nitro and phenoxy functional groups. It is classified as a hazardous substance with carcinogenic and reproductive toxicity properties, requiring careful handling and specialized safety measures in industrial applications.
What are the physicochemical properties of 2,4-dichloro-1-(4-nitrophenoxy)benzene?
2,4-dichloro-1-(4-nitrophenoxy)benzene is a solid organic compound at room temperature with a molecular weight of 284.09 g/mol. As an aromatic compound containing chlorine substituents and a nitro group, it typically exhibits limited water solubility but good solubility in organic solvents. The presence of electron-withdrawing groups (chlorine and nitro) affects its chemical reactivity and stability. Specific physical properties such as melting point and exact solubility data should be confirmed through technical documentation.
What is 2,4-dichloro-1-(4-nitrophenoxy)benzene used for?
2,4-dichloro-1-(4-nitrophenoxy)benzene is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. Its structure makes it suitable for further chemical transformations in the production of specialized compounds. Due to its hazardous classification (Carcinogenic 1B, Reproductive toxicity 1B), its use is restricted to professional industrial applications with appropriate safety controls. It may serve as a precursor for pharmaceuticals, agrochemicals, or other fine chemicals requiring specific aromatic substitution patterns.
How to handle 2,4-dichloro-1-(4-nitrophenoxy)benzene safely?
2,4-dichloro-1-(4-nitrophenoxy)benzene requires strict safety protocols due to its carcinogenic and reproductive toxicity classification. Essential protective equipment includes nitrile gloves, safety goggles, and respiratory protection in well-ventilated areas or fume hoods. Workers must wear appropriate protective clothing to prevent skin contact. Handle only in designated areas with proper engineering controls, avoid dust generation, and ensure emergency washing facilities are readily available. Training on hazardous material handling procedures is mandatory before use.
How to store 2,4-dichloro-1-(4-nitrophenoxy)benzene correctly?
2,4-dichloro-1-(4-nitrophenoxy)benzene must be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Use original containers or compatible materials, ensuring tight sealing to prevent contamination and exposure. Storage areas should be restricted to authorized personnel only, with appropriate warning signs indicating carcinogenic and reproductive hazards. Keep separated from incompatible materials such as strong oxidizers and bases. Implement regular inventory checks and ensure compliance with local hazardous material storage regulations.
What to do in case of contact with 2,4-dichloro-1-(4-nitrophenoxy)benzene?
Immediate action is critical due to the substance's toxic properties. For skin contact, remove contaminated clothing immediately and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any exposure, providing the safety data sheet for proper medical evaluation and treatment.
How to dispose of 2,4-dichloro-1-(4-nitrophenoxy)benzene appropriately?
2,4-dichloro-1-(4-nitrophenoxy)benzene requires disposal as hazardous waste through licensed waste management companies due to its carcinogenic properties and environmental hazard classification. Never dispose of in regular waste streams, sewers, or soil. Collect waste in appropriate containers, properly labeled with hazard information. Disposal must comply with local, national, and European waste regulations including the European Waste Catalogue codes. Contact specialized hazardous waste disposal services for collection and treatment through approved high-temperature incineration or other authorized methods.
How to transport 2,4-dichloro-1-(4-nitrophenoxy)benzene?
2,4-dichloro-1-(4-nitrophenoxy)benzene is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. Packages must be properly labeled with appropriate hazard labels and comply with ADR packaging requirements. Transport documents must include proper shipping names and hazard classifications. Vehicles must carry appropriate emergency equipment and drivers require ADR certification. Ensure packages are secure, properly sealed, and segregated from incompatible materials during transit. Emergency response information must be readily available during transportation.
Is 2,4-dichloro-1-(4-nitrophenoxy)benzene subject to specific regulations?
2,4-dichloro-1-(4-nitrophenoxy)benzene is subject to comprehensive European chemical regulations under REACH and CLP frameworks. Its classification as Carcinogenic 1B and Reproductive toxicity 1B triggers strict handling, labeling, and safety data sheet requirements. The substance requires proper registration for manufacturing or import above threshold quantities. Workplace exposure limits and health surveillance may apply. Users must comply with chemical safety assessments and implement appropriate risk management measures. Regular regulatory updates should be monitored as restrictions may evolve.
Where to buy 2,4-dichloro-1-(4-nitrophenoxy)benzene in Europe?
2,4-dichloro-1-(4-nitrophenoxy)benzene is available through OYSI, a specialized European distributor of technical chemicals. As a professional-grade hazardous substance, it is only supplied to qualified industrial customers with appropriate handling capabilities and safety infrastructure. OYSI ensures full regulatory compliance including proper documentation, safety data sheets, and transport arrangements. Contact OYSI directly for availability, technical specifications, and ordering procedures. Due to the substance's hazardous nature, additional qualification requirements and safety certifications may be necessary for purchase.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.