1-methoxy-4-nitrobenzene

1-methoxy-4-nitrobenzene is an aromatic organic compound with the molecular formula C7H7NO3 and CAS number 100-17-4. This chemical consists of a benzene ring substituted with a methoxy group (-OCH3) and a nitro group (-NO2) in para positions. With a molecular weight of 153.14 g/mol, it belongs to the family of nitroaromatic compounds and serves as an important intermediate in organic synthesis and chemical manufacturing processes.

1-methoxy-4-nitrobenzene appears as a pale yellow to yellow crystalline solid at room temperature. It has a characteristic aromatic odor and is moderately soluble in organic solvents such as ethanol, ether, and benzene, while being poorly soluble in water. The compound has a melting point around 54°C and demonstrates typical stability under normal storage conditions, though it should be protected from strong oxidizing agents and extreme heat.

1-methoxy-4-nitrobenzene serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of dyes, pigments, and various aromatic compounds. The compound also finds applications in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its nitro and methoxy functional groups make it a versatile building block for further chemical transformations in industrial processes.

1-methoxy-4-nitrobenzene should be handled with appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation of vapors or dust. Avoid contact with skin, eyes, and clothing. Use non-sparking tools and ensure proper grounding when transferring the material to prevent static electricity buildup during handling operations.

1-methoxy-4-nitrobenzene should be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and direct sunlight. Keep containers tightly closed and store away from incompatible materials such as strong oxidizing agents, strong bases, and reducing agents. The storage area should be equipped with appropriate spill containment measures and fire suppression systems. Maintain storage temperatures below 25°C for optimal stability.

In case of skin contact with 1-methoxy-4-nitrobenzene, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and monitor breathing. If ingested, do not induce vomiting and seek immediate medical attention while providing the safety data sheet to healthcare providers.

1-methoxy-4-nitrobenzene waste must be disposed of in accordance with local, national, and international environmental regulations. The material should be collected in appropriate containers and handed over to licensed waste disposal companies specializing in chemical waste treatment. Do not dispose of in regular trash, pour down drains, or release into the environment. Incineration at approved high-temperature facilities is typically the preferred disposal method for this type of organic compound.

1-methoxy-4-nitrobenzene is classified under ADR as Class 6.1 (toxic substances), Packing Group III. Transportation must comply with dangerous goods regulations including proper packaging, labeling, and documentation. Packages must bear appropriate hazard labels and be constructed to prevent leakage during normal transport conditions. Vehicle placarding and driver training requirements apply, and emergency response information must accompany shipments according to ADR regulations.

1-methoxy-4-nitrobenzene is regulated under REACH and CLP regulations in Europe, requiring registration and appropriate classification and labeling. While not currently listed as an SVHC (Substance of Very High Concern), users must comply with standard chemical safety requirements including safety data sheet provisions and risk assessments. Import/export may require notifications to relevant authorities, and workplace exposure limits may apply depending on national implementations of occupational health directives.

1-methoxy-4-nitrobenzene is available through OYSI, a European distributor of chemical products specializing in industrial and laboratory chemicals. OYSI provides reliable supply chains across Europe with proper documentation, safety data sheets, and regulatory compliance support. As an established chemical distributor, OYSI ensures product quality and can assist with technical specifications, logistics coordination, and regulatory requirements for European customers requiring this specialized aromatic compound.