1-methoxy-4-nitrobenzene

1-methoxy-4-nitrobenzene is an organic chemical compound with the molecular formula C7H7NO3 and CAS number 100-17-4. It belongs to the family of nitroaromatic compounds, featuring a benzene ring substituted with both a methoxy group (-OCH3) and a nitro group (-NO2) in para positions. This compound has a molecular weight of 153.14 g/mol and appears as a crystalline solid at room temperature.

1-methoxy-4-nitrobenzene presents as a pale yellow to yellow crystalline solid at room temperature with a characteristic aromatic odor. It has a melting point around 54°C and is practically insoluble in water but readily soluble in organic solvents such as ethanol, ether, and benzene. The compound exhibits stability under normal conditions but should be protected from strong oxidizing agents and excessive heat.

1-methoxy-4-nitrobenzene serves primarily as an important intermediate in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of dyes, pigments, and various pharmaceutical compounds. The compound also finds applications in the synthesis of 4-methoxyaniline through reduction processes and serves as a building block for agrochemicals and specialty chemicals in industrial processes.

1-methoxy-4-nitrobenzene should be handled with appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation. Avoid direct skin and eye contact, and ensure no smoking or open flames are present in the work area. Always wash hands thoroughly after handling and before eating or drinking.

1-methoxy-4-nitrobenzene should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed and store away from strong oxidizing agents, strong acids, and incompatible materials. The storage area should be equipped with appropriate spill containment measures and maintained at temperatures below 25°C to ensure product stability and prevent decomposition.

1-methoxy-4-nitrobenzene contact requires immediate action depending on exposure route. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. In case of eye contact, flush immediately with clean water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention. Always consult a physician if symptoms persist or worsen.

1-methoxy-4-nitrobenzene waste must be disposed of in accordance with local, national, and international environmental regulations. The compound should not be discharged into drains, water systems, or the environment. Disposal should be carried out through licensed waste management companies capable of handling chemical waste. Empty containers should also be treated as hazardous waste and disposed of through appropriate channels.

1-methoxy-4-nitrobenzene is classified under ADR as Class 6.1 (Toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation procedures. Transport vehicles must comply with ADR regulations including appropriate placarding and driver certification. Proper shipping papers and emergency response information must accompany shipments to ensure safe transportation throughout the supply chain.

1-methoxy-4-nitrobenzene is subject to various chemical regulations including REACH registration requirements in the European Union. The compound is not currently listed as a Substance of Very High Concern (SVHC) under REACH. However, it must comply with CLP regulation requirements for classification, labeling, and packaging. Users should maintain safety data sheets and ensure compliance with local occupational health and safety regulations.

1-methoxy-4-nitrobenzene is available through OYSI, a specialized European distributor of technical chemical products. OYSI provides reliable supply chains across Europe with proper documentation, quality certificates, and regulatory compliance support. As an established chemical distributor, OYSI ensures product quality and can provide technical support for various applications requiring this important chemical intermediate.