2-nitroaniline

2-nitroaniline is an organic chemical compound with the molecular formula C6H6N2O2 and CAS number 88-74-4. This aromatic amine features both an amino group and a nitro group attached to a benzene ring in ortho position. With a molecular weight of 138.12 g/mol, it appears as yellow to orange crystalline solid. It is classified as a hazardous substance with acute toxicity and potential health effects, requiring careful handling in industrial applications.

2-nitroaniline is a yellow to orange crystalline solid at room temperature with a characteristic aromatic odor. It has limited solubility in water but dissolves well in organic solvents like ethanol and acetone. The compound has a melting point around 71-73°C and exhibits stability under normal conditions. Its aromatic structure gives it UV-absorbing properties, and it can undergo various chemical reactions typical of both anilines and nitro compounds.

2-nitroaniline serves primarily as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It is widely used in the production of azo dyes, particularly yellow and orange colorants for textiles and printing inks. The compound also functions as a precursor for various chemical syntheses, including the manufacture of antioxidants, rubber chemicals, and specialty organic compounds. Its dual functional groups make it valuable in organic synthesis reactions.

2-nitroaniline requires strict safety measures due to its acute toxicity classification. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Prevent skin and eye contact, and avoid ingestion. Use non-sparking tools and equipment. Ensure emergency eyewash stations and safety showers are readily accessible when handling this substance.

2-nitroaniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers in secondary containment to prevent spills. Store away from incompatible materials such as strong oxidizers, acids, and alkalis. Maintain storage temperatures below 25°C and ensure proper labeling according to GHS requirements. Access should be restricted to trained personnel only.

In case of skin contact with 2-nitroaniline, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush eyes with clean water for 15-20 minutes. If inhaled, move the person to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. In all cases of exposure, contact emergency medical services promptly and provide the safety data sheet.

2-nitroaniline disposal must comply with local and national hazardous waste regulations due to its toxicity classification. The substance should be collected in appropriate containers and labeled clearly for hazardous waste disposal. Contact licensed waste disposal companies for proper treatment, which typically involves high-temperature incineration at specialized facilities. Never dispose of this chemical in regular waste streams, sewers, or the environment. Maintain disposal records as required by regulations.

2-nitroaniline is classified under ADR as Class 6.1 (toxic substances), Packing Group II, requiring specific transport protocols. Packages must be properly labeled with appropriate hazard symbols and shipping names. Use UN-approved packaging designed for toxic solids, and ensure vehicles are properly placarded. Transport documentation must include safety data sheets and emergency response information. Only trained personnel should handle transportation, following ADR regulations for dangerous goods.

2-nitroaniline is regulated under various European frameworks including REACH regulation for registration and evaluation. It falls under CLP regulation for classification, labeling, and packaging requirements, indicated by its GHS pictograms (GHS06, GHS08) and 'Danger' signal word. The substance is not currently listed as an SVHC (Substance of Very High Concern). Industrial users must comply with occupational exposure limits and safety requirements established by national authorities.

2-nitroaniline is available through OYSI, a trusted European distributor of chemical products. OYSI provides high-quality 2-nitroaniline with proper documentation including safety data sheets and certificates of analysis. As a specialized chemical distributor, OYSI ensures compliance with European regulations and offers technical support for industrial applications. Contact OYSI directly for availability, specifications, and delivery options to your location within Europe.