N-phenylaniline
C12H11N
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Identification
- CAS Number
- 122-39-4
- EC Number
- 204-539-4
- UN Number
- 2811
- Index Number
- 612-026-00-5
- PubChem CID
- 11487
Physical-chemical properties
- Molecular Formula
- C12H11N
- Molar Mass
- 169.22 g/mol
- IUPAC Name
- N-phenylaniline
Chemical Identifiers
- InChI
- InChI=1S/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H
- InChI Key
- DMBHHRLKUKUOEG-UHFFFAOYSA-N
Overview
N-phenylaniline (CAS 122-39-4) is an aromatic amine compound with significant industrial applications and notable toxicity properties requiring careful handling protocols. N-phenylaniline, also known as diphenylamine, represents a crucial intermediate in various chemical manufacturing processes. This crystalline compound belongs to the secondary aromatic amine family and exhibits distinctive chemical properties that make it valuable across multiple industrial sectors. With the molecular formula C12H11N and a molecular weight of 169.22 g/mol, this substance demonstrates moderate stability under normal conditions while requiring specific safety considerations due to its classification profile. The compound carries significant safety implications, classified with Acute Toxicity Category 3 across multiple exposure routes and Specific Target Organ Toxicity (Repeated Exposure) Category 2. Its environmental impact classification as Aquatic Acute and Chronic Category 1 necessitates careful environmental handling protocols. The presence of GHS pictograms GHS06, GHS08, and GHS09 indicates acute toxicity, health hazard, and environmental dangers respectively, emphasizing the importance of appropriate personal protective equipment and containment measures during handling and storage. Industrial applications of N-phenylaniline span several sectors, including its use as an antioxidant in rubber and polymer industries, where it prevents degradation and extends material lifespan. The compound also serves as an intermediate in dye manufacturing and pharmaceutical synthesis. Related compounds in this chemical family include N-methylaniline and 2-chloroaniline, which share similar aromatic amine structures but differ in their specific applications and safety profiles. As a specialized European distributor of technical chemicals, OYSI maintains reliable supply chains for N-phenylaniline to support diverse industrial requirements across the European market.
Safety & Classification
Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE 2 *; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2811 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | N-Phenylanilin, fest |
| Marine Pollutant | No |
Frequently Asked Questions
What is N-phenylaniline?
N-phenylaniline is an organic chemical compound with the molecular formula C12H11N and CAS number 122-39-4. It belongs to the family of aromatic amines, featuring two benzene rings connected through a nitrogen atom. With a molecular weight of 169.22 g/mol, this substance is classified as hazardous due to its acute toxicity and potential for specific target organ toxicity. It also poses environmental risks to aquatic life.
What are the physicochemical properties of N-phenylaniline?
N-phenylaniline is typically a solid crystalline substance at room temperature with a characteristic aromatic amine odor. It appears as white to light yellow crystals or powder that may darken upon exposure to air and light. The compound has limited solubility in water but dissolves well in organic solvents such as ethanol, benzene, and ether. Its aromatic structure contributes to its stability and specific chemical reactivity patterns.
What is N-phenylaniline used for?
N-phenylaniline is primarily used as an intermediate in the production of dyes, pigments, and pharmaceuticals. It serves as a key building block in the synthesis of various organic compounds, particularly in the manufacture of antioxidants for rubber and plastics. The compound is also utilized in the production of certain pesticides and as a stabilizer in polymer chemistry. Its applications are mainly restricted to industrial and professional use due to safety considerations.
How to handle N-phenylaniline safely?
N-phenylaniline requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure no ingestion occurs. Personnel should be trained in proper handling procedures and emergency response. Regular health monitoring may be necessary for workers with potential exposure to this substance.
How to store N-phenylaniline correctly?
N-phenylaniline should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed and store separately from strong oxidizing agents, acids, and food products. The storage area should be equipped with appropriate spill containment measures and emergency equipment. Maintain temperatures below 25°C when possible and ensure proper labeling according to GHS requirements. Regular inspection of containers is recommended.
What to do in case of contact with N-phenylaniline?
Immediate action is required for any contact with N-phenylaniline. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes. If inhaled, move the person to fresh air and monitor breathing. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any significant exposure.
How to dispose of N-phenylaniline appropriately?
N-phenylaniline disposal must comply with local, national, and EU waste regulations as it is classified as hazardous waste. The substance should never be discharged to sewers, waterways, or soil due to its aquatic toxicity. Disposal should be arranged through licensed hazardous waste contractors who can ensure proper treatment, typically involving high-temperature incineration. Contaminated packaging and materials also require hazardous waste disposal. Always consult local environmental authorities for specific disposal requirements.
How to transport N-phenylaniline?
N-phenylaniline is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation. It must be packaged in UN-approved containers with proper hazard labels and documentation. Transport vehicles must carry appropriate emergency equipment and personnel should be trained in hazardous goods handling. The substance requires toxic substance placarding during transport and must be accompanied by proper shipping papers and emergency response information.
Is N-phenylaniline subject to specific regulations?
N-phenylaniline is subject to multiple European regulations including REACH registration requirements and CLP classification obligations. As a toxic substance, it falls under various occupational health and safety directives requiring risk assessments and exposure monitoring. The compound is also regulated under environmental legislation due to its aquatic toxicity. While not currently listed as a SVHC, its hazard classification means it may be subject to authorization or restriction procedures in the future.
Where to buy N-phenylaniline in Europe?
N-phenylaniline is available through OYSI, a specialized European distributor of technical chemicals serving industrial and professional customers across Europe. OYSI provides this substance with full regulatory compliance, proper documentation, and technical support. As a restricted chemical due to its hazard classification, purchase is limited to qualified industrial users with appropriate handling capabilities and regulatory permits. Contact OYSI directly for availability, specifications, and regulatory requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.