3,5-dimethylaniline
C8H11N
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Identification
- CAS Number
- 108-69-0
- EC Number
- 203-607-0
- UN Number
- 1711
- Index Number
- 612-027-00-0
- PubChem CID
- 7949
Physical-chemical properties
- Molecular Formula
- C8H11N
- Molar Mass
- 121.18 g/mol
- IUPAC Name
- 3,5-dimethylaniline
Chemical Identifiers
- InChI
- InChI=1S/C8H11N/c1-6-3-7(2)5-8(9)4-6/h3-5H,9H2,1-2H3
- InChI Key
- MKARNSWMMBGSHX-UHFFFAOYSA-N
Overview
3,5-dimethylaniline (CAS 108-69-0) is an aromatic amine compound characterized by two methyl substituents on the benzene ring and significant toxicity properties. This chemical intermediate belongs to the substituted aniline family, featuring a benzene ring with an amino group (-NH2) and two methyl groups positioned at the 3 and 5 positions. With a molecular formula of C8H11N and molecular weight of 121.18 g/mol, 3,5-dimethylaniline presents as a crystalline solid at room temperature. The compound's structure influences its reactivity and makes it valuable for various synthetic applications in organic chemistry. Safety considerations are paramount when handling 3,5-dimethylaniline, as it carries multiple acute toxicity classifications (Acute Tox. 3) for oral, dermal, and inhalation exposure routes. The substance also presents specific target organ toxicity concerns with repeated exposure (STOT RE 2) and chronic aquatic toxicity (Aquatic Chronic 2). These hazard classifications require appropriate personal protective equipment, adequate ventilation, and strict adherence to safety protocols during storage, handling, and processing. The compound finds primary application in the pharmaceutical industry as an intermediate for drug synthesis, particularly in the production of various therapeutic compounds. Additionally, it serves as a building block in dye manufacturing, where its aromatic amine structure provides reactive sites for color development. The chemical industry also utilizes 3,5-dimethylaniline in specialty chemical synthesis, often in conjunction with related compounds such as N,N-diethylaniline for specific reaction pathways. As a technical chemical distributor, OYSI maintains reliable supply chains for 3,5-dimethylaniline to support pharmaceutical, chemical, and industrial manufacturing operations across European markets.
Safety & Classification
Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE 2 *; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1711 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | 3,5-Xylidin |
| Marine Pollutant | No |
Frequently Asked Questions
What is 3,5-dimethylaniline?
3,5-dimethylaniline is an aromatic amine compound with the molecular formula C8H11N and CAS number 108-69-0. This chemical belongs to the aniline family, characterized by an amino group attached to a benzene ring with two methyl substituents at positions 3 and 5. With a molecular weight of 121.18 g/mol, it serves as an important intermediate in chemical synthesis and industrial applications.
What are the physicochemical properties of 3,5-dimethylaniline?
3,5-dimethylaniline is typically a liquid or low-melting solid at room temperature with a characteristic amine odor. As an aromatic amine, it exhibits moderate solubility in water and good solubility in organic solvents such as alcohol and ether. The compound has a molecular weight of 121.18 g/mol and contains both aromatic and aliphatic characteristics due to its benzene ring structure with methyl substituents.
What is 3,5-dimethylaniline used for?
3,5-dimethylaniline is primarily used as a chemical intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It serves as a building block for manufacturing various organic compounds, including specialty chemicals and fine chemicals. The compound is also utilized in research and development applications for creating new materials and chemical formulations in industrial and laboratory settings.
How to handle 3,5-dimethylaniline safely?
3,5-dimethylaniline must be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods due to its toxicity classification (Acute Tox. 3). Avoid skin contact, inhalation, and ingestion. The compound requires careful handling due to its GHS06 and GHS08 pictograms indicating acute toxicity and health hazards.
How to store 3,5-dimethylaniline correctly?
3,5-dimethylaniline should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and incompatible materials. Keep containers away from oxidizing agents and strong acids. Storage areas should be equipped with appropriate spill containment measures and restricted access due to the compound's toxicity classification. Maintain proper labeling according to GHS requirements with danger signal word.
What to do in case of contact with 3,5-dimethylaniline?
Immediate action is required upon contact with 3,5-dimethylaniline due to its acute toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for specific emergency procedures.
How to dispose of 3,5-dimethylaniline properly?
3,5-dimethylaniline must be disposed of as hazardous waste according to local and European regulations due to its toxicity and environmental hazard classification (Aquatic Chronic 2). Contact licensed waste disposal companies specialized in chemical waste management. Never discharge into sewers, waterways, or soil. Contaminated packaging should also be treated as hazardous waste and disposed of through appropriate channels following regulatory requirements.
How to transport 3,5-dimethylaniline?
3,5-dimethylaniline is classified as ADR Class 6.1 (toxic substances) Packing Group II, requiring specific transport regulations compliance. Packages must bear proper hazard labels and documentation according to dangerous goods transport regulations. Only certified carriers with appropriate training and equipment should handle transportation. Proper packaging, labeling, and shipping papers are mandatory for legal transport within Europe.
Is 3,5-dimethylaniline subject to specific regulations?
3,5-dimethylaniline is subject to various European chemical regulations including REACH registration requirements and CLP classification standards. The compound is classified with multiple hazard classes including acute toxicity and STOT RE 2, requiring appropriate risk management measures. While not currently listed as SVHC, users must comply with occupational exposure limits and safety requirements under relevant chemical safety legislation.
Where to buy 3,5-dimethylaniline in Europe?
3,5-dimethylaniline is available through OYSI, a European distributor of specialty chemicals and technical products. As an established chemical distributor, OYSI provides quality 3,5-dimethylaniline with proper documentation, safety data sheets, and regulatory compliance support. Contact OYSI directly for availability, specifications, packaging options, and delivery throughout Europe while ensuring all regulatory requirements are met.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.