2-chloroaniline

2-chloroaniline is an aromatic amine compound with the molecular formula C6H6ClN and CAS number 95-51-2. This organic chemical features a benzene ring substituted with both an amino group (-NH2) and a chlorine atom in the ortho position. With a molecular weight of 127.57 g/mol, it serves as an important intermediate in chemical synthesis and pharmaceutical manufacturing.

2-chloroaniline is a yellow to amber liquid at room temperature with a characteristic amine odor. It has a boiling point of approximately 208°C and a melting point around -14°C. The compound is slightly soluble in water but readily dissolves in organic solvents like ethanol, ether, and benzene. It is sensitive to light and air oxidation, which can cause darkening over time.

2-chloroaniline is primarily used as an intermediate in the synthesis of pharmaceuticals, dyes, and agrochemicals. It serves as a precursor for manufacturing various pharmaceutical compounds, including analgesics and anti-inflammatory drugs. In the chemical industry, it's utilized for producing azo dyes, pigments, and herbicides. Additionally, it finds application in the synthesis of specialty chemicals and research compounds.

2-chloroaniline should be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation exposure. Avoid skin and eye contact, and prevent ingestion. Use non-sparking tools and equipment, and ensure proper grounding to prevent static electricity buildup during handling operations.

2-chloroaniline should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep containers away from strong oxidizing agents, acids, and bases to prevent incompatible reactions. Storage areas should be equipped with appropriate spill containment measures and maintained at temperatures below 25°C to preserve product stability and prevent degradation.

In case of skin contact with 2-chloroaniline, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a physician after any exposure incident.

2-chloroaniline must be disposed of according to local and national hazardous waste regulations as it is classified as toxic waste. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Do not discharge into sewers, waterways, or soil. Small quantities can be incinerated at authorized high-temperature facilities with appropriate emission controls. Always consult local environmental authorities for specific disposal requirements.

2-chloroaniline is classified under ADR as Class 6.1 (Toxic substances), Packing Group II. It must be transported in UN-approved packaging with proper labeling and documentation. Vehicles must carry appropriate placards and emergency response information. Drivers require hazardous materials training certification. Shipments must comply with quantity limitations and routing restrictions as specified in international dangerous goods regulations.

2-chloroaniline is subject to various regulatory frameworks including REACH registration requirements in Europe for commercial use. It must comply with CLP regulation for classification, labeling, and packaging. The substance may be subject to workplace exposure limits and requires safety data sheets for commercial distribution. Users must ensure compliance with local occupational health and environmental regulations before handling or processing.

2-chloroaniline is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. OYSI provides high-quality chemical products with proper documentation, safety data sheets, and regulatory compliance support. As an established chemical distributor, OYSI ensures reliable supply chains and technical expertise to support your industrial applications and requirements throughout Europe.