2-chloroaniline

2-chloroaniline is an organic chemical compound with the molecular formula C6H6ClN and CAS number 27134-26-5. It belongs to the family of chlorinated anilines, featuring an amino group (-NH2) and a chlorine atom attached to a benzene ring in ortho position. This aromatic amine has a molecular weight of 127.57 g/mol and is classified as a hazardous substance requiring careful handling due to its toxic properties and environmental impact.

2-chloroaniline is typically a pale yellow to amber liquid at room temperature with a characteristic amine-like odor. As an aromatic amine, it exhibits moderate solubility in water and good solubility in organic solvents such as ethanol and benzene. The compound is sensitive to light and air, which can cause oxidation and darkening. Its boiling point and melting point fall within typical ranges for substituted anilines, making it stable under normal storage conditions when properly handled.

2-chloroaniline serves primarily as an important intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is commonly used in the production of herbicides, fungicides, and various pharmaceutical compounds. The chemical industry utilizes it as a building block for manufacturing pigments, particularly azo dyes, and as a precursor for other chlorinated aromatic compounds. Its versatility in organic synthesis makes it valuable for producing specialty chemicals and fine chemical products.

Safe handling of 2-chloroaniline requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. The compound is classified as Acute Tox. 3 with GHS06 and GHS08 pictograms, indicating serious health hazards. Avoid skin contact, inhalation, and ingestion. Use non-sparking tools and ensure proper grounding to prevent static electricity buildup during handling operations.

2-chloroaniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers away from incompatible materials such as strong oxidizing agents, acids, and bases. Storage areas must be equipped with appropriate spill containment measures due to its aquatic toxicity classification. Maintain storage temperatures within recommended ranges and ensure containers are properly labeled according to CLP regulations with appropriate hazard pictogrammes.

In case of skin contact with 2-chloroaniline, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move the person to fresh air immediately and seek medical attention. For eye contact, rinse eyes with clean water for at least 15 minutes and remove contact lenses if present. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet.

2-chloroaniline must be disposed of as hazardous waste through licensed waste management companies in accordance with local and European waste regulations. Due to its aquatic toxicity classification (Aquatic Acute 1, Aquatic Chronic 1), it cannot be discharged into water systems or sewers. Incineration at high temperatures in authorized facilities is typically the preferred disposal method. Small quantities should be collected in appropriate containers and labeled clearly for hazardous waste pickup. Never dispose of in regular trash or down drains.

2-chloroaniline is classified under ADR as Class 6.1 (toxic substances), Packing Group II, requiring specialized transport procedures. Packages must bear appropriate hazard labels and be transported by drivers with ADR certification. The substance must be packaged in UN-approved containers suitable for toxic liquids. Transport vehicles require proper placarding and emergency equipment. Documentation must include transport documents specifying the proper shipping name, UN number, and emergency response information according to dangerous goods regulations.

2-chloroaniline is subject to REACH regulation requiring registration for import/manufacture above certain tonnages in the EU. It falls under CLP classification with mandatory labeling showing GHS06, GHS08, and GHS09 pictogrammes and 'Danger' signal word. The substance is not currently listed as SVHC (Substance of Very High Concern). Companies must comply with occupational exposure limits and environmental discharge restrictions. Additional national regulations may apply for industrial use, storage, and worker protection measures.

2-chloroaniline is available through OYSI, a European distributor specializing in technical chemicals and industrial raw materials. As an established chemical supplier, OYSI can provide 2-chloroaniline with appropriate documentation including safety data sheets, certificates of analysis, and regulatory compliance information. The company serves various European markets and can advise on proper handling, storage requirements, and regulatory compliance. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.