N-ethylaniline

C8H11N

CAS103-69-5
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
Danger

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Identification

CAS Number
103-69-5
EC Number
203-135-5
UN Number
2272
Index Number
612-053-00-2
PubChem CID
7670

Physical-chemical properties

Molecular Formula
C8H11N
Molar Mass
121.18 g/mol
IUPAC Name
N-ethylaniline

Chemical Identifiers

InChI
InChI=1S/C8H11N/c1-2-9-8-6-4-3-5-7-8/h3-7,9H,2H2,1H3
InChI Key
OJGMBLNIHDZDGS-UHFFFAOYSA-N

Overview

N-ethylaniline (CAS 103-69-5) is an aromatic amine compound featuring an ethyl group attached to the nitrogen atom of aniline, widely used in chemical synthesis and industrial applications. This organic compound belongs to the family of substituted anilines, characterized by its molecular formula C8H11N and molecular weight of 121.18 g/mol. N-ethylaniline presents as a colorless to pale yellow liquid with a characteristic amine odor, demonstrating typical properties of aromatic secondary amines. The compound is structurally related to other aniline derivatives such as N-methylaniline, sharing similar chemical reactivity patterns while offering distinct synthetic advantages due to its ethyl substitution. From a safety perspective, N-ethylaniline requires careful handling as it carries significant hazard classifications including Acute Toxicity Category 3 for multiple exposure routes and Specific Target Organ Toxicity (Repeated Exposure) Category 2. The substance displays GHS06 and GHS08 pictograms with a "Danger" signal word, reflecting its potential health impacts. Transportation falls under ADR Class 6.1, emphasizing the need for proper packaging and handling protocols during logistics operations. Industrial applications of N-ethylaniline primarily center on its role as an intermediate in pharmaceutical synthesis, where it serves as a building block for various drug compounds. The chemical also finds application in the production of dyes and pigments, particularly in the manufacture of azo dyes where its aromatic amine structure provides essential coupling capabilities. Additionally, N-ethylaniline functions as a precursor in rubber chemical production and specialty polymer synthesis. OYSI maintains reliable supply chains for N-ethylaniline, ensuring consistent availability for European industrial customers requiring this specialized aromatic amine for their manufacturing processes.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE 2 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2272
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameN-Ethylanilin
Marine PollutantNo

Frequently Asked Questions

What is N-ethylaniline?

N-ethylaniline is an aromatic amine compound with the chemical formula C8H11N and CAS number 103-69-5. It consists of an aniline molecule where one hydrogen atom on the nitrogen is replaced by an ethyl group. With a molecular weight of 121.18 g/mol, this substance is classified as hazardous due to its acute toxicity and potential for causing specific target organ toxicity after repeated exposure.

What are the physicochemical properties of N-ethylaniline?

N-ethylaniline is typically a colorless to pale yellow liquid at room temperature with a characteristic amine odor. As an aromatic amine derivative, it has moderate polarity and limited water solubility but dissolves well in organic solvents like alcohols and ethers. The compound has a molecular weight of 121.18 g/mol and contains both aromatic and aliphatic structural elements, giving it distinctive chemical reactivity patterns.

What is N-ethylaniline used for?

N-ethylaniline serves primarily as an intermediate in organic synthesis and chemical manufacturing processes. It is commonly used in the production of dyes, pharmaceuticals, and other fine chemicals where aromatic amine functionality is required. The compound also finds applications in research laboratories as a building block for more complex molecules and in analytical chemistry as a reference standard or reagent.

How to handle N-ethylaniline safely?

N-ethylaniline requires careful handling due to its acute toxicity classification (Acute Tox. 3) and potential for organ damage. Workers must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection when exposure risks exist. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin contact and ensure proper training on emergency procedures before handling.

How to store N-ethylaniline correctly?

N-ethylaniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. The storage area must be secure and accessible only to trained personnel due to the substance's toxicity classification. Containers should be properly labeled with hazard information and stored according to local regulations for toxic substances. Regular inspection of containers for leaks or damage is essential.

What to do in case of contact with N-ethylaniline?

Immediate action is required following N-ethylaniline contact due to its acute toxicity. For skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes. If inhaled, move the person to fresh air immediately. Seek medical attention promptly in all cases of exposure and provide safety data sheet information to medical personnel.

How to dispose of N-ethylaniline properly?

N-ethylaniline must be disposed of as hazardous waste according to local and national environmental regulations. The substance cannot be discharged into sewers or the environment due to its toxicity classification. Disposal should only be conducted through licensed hazardous waste disposal companies that can handle toxic organic compounds. Empty containers may also require special disposal procedures and should not be reused for other purposes.

How to transport N-ethylaniline?

N-ethylaniline is classified under ADR as Class 6.1 (toxic substances), Packing Group III, requiring specific transport protocols. Packages must be properly labeled with appropriate hazard markings and documentation. Transport vehicles need placarding and drivers require hazardous materials training. The substance must be packaged in UN-approved containers and transported according to dangerous goods regulations to ensure safety during transit.

Is N-ethylaniline subject to specific regulations?

N-ethylaniline is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification for hazard communication. The substance is not currently listed as an SVHC (Substance of Very High Concern), but its acute toxicity classification means it falls under workplace safety regulations and chemical control measures. Users must comply with occupational exposure limits and safety requirements in their jurisdictions.

Where to buy N-ethylaniline in Europe?

N-ethylaniline is available through OYSI, a European distributor specializing in chemical products for industrial and professional applications. As an established chemical distributor, OYSI can provide properly classified and documented N-ethylaniline with appropriate safety data sheets and regulatory compliance documentation. Contact OYSI directly for availability, specifications, and ordering information for your specific requirements in the European market.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.