N-ethylaniline

C8H11N

CAS103-69-5
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
Danger

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Identification

CAS Number
103-69-5
EC Number
203-135-5
UN Number
2272
Index Number
612-053-00-2
PubChem CID
7670

Physical-chemical properties

Molecular Formula
C8H11N
Molar Mass
121.18 g/mol
IUPAC Name
N-ethylaniline

Chemical Identifiers

InChI
InChI=1S/C8H11N/c1-2-9-8-6-4-3-5-7-8/h3-7,9H,2H2,1H3
InChI Key
OJGMBLNIHDZDGS-UHFFFAOYSA-N

Overview

N-ethylaniline (CAS 103-69-5) is an aromatic amine compound featuring an ethyl group attached to the nitrogen atom of aniline, commonly used as an industrial chemical intermediate. This important aromatic amine serves as a versatile building block in organic synthesis and industrial chemical manufacturing. With the molecular formula C8H11N and a molecular weight of 121.18 g/mol, N-ethylaniline belongs to the family of substituted anilines, where an ethyl group replaces one hydrogen atom on the amino group of the parent aniline molecule. This structural modification significantly influences its chemical reactivity and industrial applications compared to unsubstituted aniline or related compounds like N-methylaniline. N-ethylaniline presents important safety considerations that require careful handling protocols. Classified under acute toxicity category 3 for multiple exposure routes and specific target organ toxicity category 2 for repeated exposure, this compound requires appropriate safety measures during storage, handling, and processing. The GHS classification includes pictograms GHS06 and GHS08, indicating both acute toxicity and health hazards, with "Danger" as the signal word. Transportation falls under ADR class 6.1, reflecting its toxic nature. Industrial applications of N-ethylaniline include its use as an intermediate in pharmaceutical synthesis, where it serves as a precursor for various medicinal compounds. The chemical industry also employs it in the production of dyes, pigments, and specialty chemicals. Additionally, it functions as a component in certain polymerization processes and as a chemical intermediate for manufacturing rubber accelerators and antioxidants. OYSI maintains reliable supplies of N-ethylaniline to support diverse industrial applications across European markets, ensuring consistent availability for technical and manufacturing requirements.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE 2 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2272
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameN-Ethylanilin
Marine PollutantNo

Frequently Asked Questions

What is N-ethylaniline?

N-ethylaniline is an organic chemical compound with the molecular formula C8H11N and CAS number 103-69-5. It belongs to the family of aromatic amines, specifically an N-alkylated derivative of aniline where an ethyl group is attached to the nitrogen atom. With a molecular weight of 121.18 g/mol, this substance is classified as hazardous with acute toxicity properties and potential for organ damage upon repeated exposure.

What are the physicochemical properties of N-ethylaniline?

N-ethylaniline is typically a colorless to pale yellow liquid at room temperature with a characteristic amine odor. As an aromatic amine derivative, it exhibits moderate polarity due to the nitrogen atom while maintaining hydrophobic characteristics from the benzene ring and ethyl group. The compound has limited water solubility but is generally soluble in organic solvents such as alcohols, ethers, and hydrocarbons.

What is N-ethylaniline used for?

N-ethylaniline serves primarily as an intermediate in organic synthesis and chemical manufacturing processes. It is commonly used in the production of dyes, pigments, and pharmaceutical intermediates. The compound also finds application in the synthesis of rubber chemicals, antioxidants, and various specialty chemicals. Its aromatic amine structure makes it valuable for creating complex organic molecules in industrial chemistry applications.

How to handle N-ethylaniline safely?

N-ethylaniline requires careful handling due to its acute toxicity classification (Acute Tox. 3). Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection when vapor exposure is possible. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Emergency eyewash stations and safety showers should be readily accessible in work areas.

How to store N-ethylaniline correctly?

N-ethylaniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers upright and protect from physical damage. Storage areas should be equipped with appropriate spill containment measures and maintained at stable temperatures. Ensure proper labeling with hazard information and restrict access to authorized personnel only.

What to do in case of contact with N-ethylaniline?

Immediate action is required upon contact with N-ethylaniline due to its toxicity. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. In case of eye contact, flush immediately with clean water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult emergency services for serious exposures.

How to dispose of N-ethylaniline appropriately?

N-ethylaniline disposal must comply with local and national hazardous waste regulations due to its toxic classification. The substance cannot be disposed of in regular waste streams or sewers. Arrange disposal through licensed hazardous waste contractors who can handle toxic organic compounds. Small quantities may require specific treatment methods such as incineration at authorized facilities. Always consult local environmental authorities for specific disposal requirements.

How to transport N-ethylaniline?

N-ethylaniline is classified under ADR as Class 6.1 (toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging standards, labeling with appropriate hazard symbols, and transport documentation. Vehicles must carry appropriate emergency equipment and drivers need proper training for hazardous materials transport. Shipping containers must meet UN specification requirements for toxic liquids.

Is N-ethylaniline subject to particular regulations?

N-ethylaniline is subject to REACH regulation requiring registration for manufacture or import in quantities above one tonne per year. The substance falls under CLP classification as Acute Tox. 3 and STOT RE 2, requiring appropriate hazard communication through safety data sheets and labeling. It is not currently listed as a SVHC (Substance of Very High Concern), but users must comply with occupational exposure limits and risk management measures.

Where to buy N-ethylaniline in Europe?

N-ethylaniline is available through OYSI, a trusted European distributor of specialty chemicals and industrial raw materials. OYSI provides reliable supply chains across European markets with proper documentation, safety data sheets, and regulatory compliance support. As a specialized chemical distributor, OYSI ensures product quality and proper handling throughout the supply chain while supporting customers with technical expertise and regulatory guidance.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.