2-methoxyethanol

C3H8O2

CAS109-86-4
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
109-86-4
EC Number
203-713-7
UN Number
1188
Index Number
603-011-00-4
PubChem CID
8019

Physical-chemical properties

Molecular Formula
C3H8O2
Molar Mass
76.09 g/mol
IUPAC Name
2-methoxyethanol

Chemical Identifiers

InChI
InChI=1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
InChI Key
XNWFRZJHXBZDAG-UHFFFAOYSA-N

Overview

2-methoxyethanol (CAS 109-86-4) is a glycol ether solvent with excellent solubility properties and moderate volatility characteristics. This versatile chemical compound, also known by its IUPAC name 2-methoxyethanol, belongs to the glycol ether family and serves as an important industrial solvent across multiple applications. With its molecular formula C3H8O2 and molecular weight of 76.09 g/mol, this colorless liquid exhibits unique dual solubility characteristics, being miscible with both water and many organic solvents due to its ether and alcohol functional groups. The compound's classification under multiple hazard categories requires careful handling protocols. It carries a Class 3 ADR rating as a flammable liquid, with GHS pictograms indicating fire hazard (GHS02), health hazard (GHS08), and exclamation mark (GHS07) warnings. The Repr. 1B classification signifies reproductive toxicity concerns, while the Acute Tox. 4 ratings across multiple exposure routes emphasize the importance of proper safety measures during handling and storage. In industrial applications, 2-methoxyethanol functions primarily as a high-performance solvent in coating formulations, particularly in automotive and industrial paints where its slow evaporation rate provides excellent flow and leveling properties. The electronics industry utilizes this compound in photoresist strippers and cleaning solutions, while the textile sector employs it in dyeing processes. Unlike related compounds such as 2-ethoxyethyl acetate, which offers different evaporation characteristics, 2-methoxyethanol provides a unique balance of solvency power and drying time that makes it valuable in specialized formulations. OYSI maintains reliable supply chains for 2-methoxyethanol, ensuring consistent availability for European industrial customers requiring this specialized glycol ether solvent.

Safety & Classification

Danger
Classification:

Flam. Liq. 3; Repr. 1B; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1188
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameEthylenglycolmonomethylether
Marine PollutantNo

Frequently Asked Questions

What is 2-methoxyethanol?

2-methoxyethanol is an organic solvent belonging to the glycol ether family with the molecular formula C3H8O2 and CAS number 109-86-4. This chemical compound has a molecular weight of 76.09 g/mol and is classified as a dangerous substance due to its flammable, reproductive toxic, and acutely toxic properties. It is commonly used in industrial applications as a solvent and chemical intermediate, requiring careful handling due to its hazardous classification.

What are the physicochemical properties of 2-methoxyethanol?

2-methoxyethanol is a colorless liquid at room temperature with a mild, ether-like odor characteristic of glycol ethers. It is completely miscible with water and most organic solvents, making it an excellent coupling agent. The compound has a relatively low molecular weight of 76.09 g/mol and exhibits good volatility. Its dual hydrophilic and lipophilic character allows it to dissolve both polar and non-polar substances effectively.

What is 2-methoxyethanol used for?

2-methoxyethanol serves primarily as a solvent in industrial applications, particularly for resins, lacquers, and dyes due to its excellent solvating properties. It is used in the formulation of paints, coatings, and printing inks where its coupling properties are valuable. The compound also functions as a chemical intermediate in synthesis reactions and finds application in cleaning formulations. However, its reproductive toxicity has led to restricted use in many consumer applications.

How to handle 2-methoxyethanol safely?

2-methoxyethanol requires strict safety precautions due to its reproductive toxicity and flammable nature. Workers must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin contact completely as the substance can be absorbed through skin. Keep away from ignition sources and ensure proper grounding of equipment.

How to store 2-methoxyethanol correctly?

2-methoxyethanol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. As a Class 3 flammable liquid, it must be kept away from ignition sources and incompatible materials such as strong oxidizing agents. Storage areas should comply with fire safety regulations for flammable liquids. Containers should be properly labeled and stored in appropriate secondary containment to prevent environmental release.

What to do in case of contact with 2-methoxyethanol?

Immediate action is crucial in case of 2-methoxyethanol exposure due to its toxic properties. For skin contact, remove contaminated clothing immediately and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for at least 15 minutes. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention, informing healthcare providers about the substance involved.

How to dispose of 2-methoxyethanol properly?

2-methoxyethanol must be disposed of as hazardous waste in accordance with local and European waste regulations. It cannot be disposed of down drains or with regular waste due to its toxicity and environmental impact. Waste should be collected in appropriate containers and handed over to licensed hazardous waste disposal companies. Contaminated materials, equipment, and empty containers also require proper hazardous waste disposal following applicable environmental protection regulations.

How to transport 2-methoxyethanol?

2-methoxyethanol is classified under ADR transport regulations as Class 3 (flammable liquid), Packing Group III, indicating moderate danger during transport. It must be packaged in approved containers and properly labeled with appropriate hazard markings and transport documentation. Vehicles must comply with ADR requirements for flammable liquids transport, including proper ventilation and emergency equipment. Transport personnel require appropriate training for handling hazardous materials according to international transport regulations.

Is 2-methoxyethanol subject to particular regulations?

2-methoxyethanol is subject to strict European regulations under REACH and CLP due to its reproductive toxicity (category 1B) and other hazardous properties. The substance requires safety data sheets and proper hazard communication. Its use is restricted in consumer products under various EU regulations due to health concerns. Companies handling this substance must comply with occupational exposure limits and may require authorization for certain uses under REACH regulatory framework.

Where to buy 2-methoxyethanol in Europe?

2-methoxyethanol is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. As a professional chemical distributor, OYSI provides proper documentation, safety data sheets, and regulatory compliance support for this regulated substance. Due to its hazardous classification and regulatory restrictions, 2-methoxyethanol is only available to qualified industrial users with appropriate handling capabilities and safety measures in place.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.