Furan

C4H4O

furan

CAS110-00-9
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
110-00-9
EC Number
203-727-3
UN Number
2389
Index Number
603-105-00-5
PubChem CID
8029

Physical-chemical properties

Molecular Formula
C4H4O
Molar Mass
68.07 g/mol
IUPAC Name
furan

Chemical Identifiers

InChI
InChI=1S/C4H4O/c1-2-4-5-3-1/h1-4H
InChI Key
YLQBMQCUIZJEEH-UHFFFAOYSA-N

Overview

Furan (CAS 110-00-9) is a heterocyclic organic compound featuring a five-membered aromatic ring with one oxygen atom and high flammability characteristics. This colorless, volatile liquid represents one of the simplest oxygen-containing heterocycles in organic chemistry, serving as a fundamental building block in various chemical processes. Furan exhibits distinctive aromatic properties due to its conjugated π-electron system, where the oxygen atom contributes two electrons to the aromatic sextet. The compound demonstrates significant reactivity, particularly in Diels-Alder reactions and electrophilic substitution processes, making it valuable for synthetic chemistry applications. From a safety perspective, furan presents multiple hazard classifications requiring careful handling protocols. The substance is classified as an extremely flammable liquid (Category 1) with a flash point well below room temperature, necessitating strict fire prevention measures. Additionally, furan carries serious health warnings as a Category 1B carcinogen and Category 2 mutagen, requiring appropriate personal protective equipment and controlled exposure conditions. The compound also exhibits acute toxicity properties and potential for skin irritation, emphasizing the importance of proper safety training and containment procedures. Industrial applications of furan primarily focus on chemical synthesis and pharmaceutical intermediates. The compound serves as a precursor for furfural production and finds application in polymer chemistry for developing specialized resins and materials. Similar to styrene in polymerization applications, furan can participate in various condensation reactions to form furan-based polymers with unique properties. Furan's reactivity profile makes it particularly useful in fine chemical manufacturing, where its ability to undergo selective transformations enables the synthesis of complex molecular structures. The pharmaceutical industry utilizes furan derivatives for developing various therapeutic compounds, leveraging the heterocycle's structural versatility. OYSI maintains reliable supply chains for furan, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate.

Safety & Classification

Danger
Classification:

Flam. Liq. 1; Carc. 1B; Muta. 2; Acute Tox. 4 *; Acute Tox. 4 *; STOT RE 2 *; Skin Irrit. 2; Aqua...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H224

Extremely flammable liquid and vapour.

H350

May cause cancer.

H341

Suspected of causing genetic defects.

H332

Harmful if inhaled.

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H412

Harmful to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2389
ADR Class3
Packing GroupI
Tunnel CodeD/E
Proper Shipping NameFuran
Marine PollutantNo

Frequently Asked Questions

What is furan?

Furan is a heterocyclic organic compound with the molecular formula C4H4O and CAS number 110-00-9. It consists of a five-membered aromatic ring containing four carbon atoms and one oxygen atom. With a molecular weight of 68.07 g/mol, furan is classified as a highly flammable liquid and a potential carcinogen. It serves as an important building block in organic synthesis and chemical manufacturing processes.

What are the physicochemical properties of furan?

Furan is a colorless, volatile liquid at room temperature with a characteristic ether-like odor. It has a low boiling point of 31.3°C and is highly volatile. The compound is moderately soluble in water and miscible with most organic solvents including alcohols, ethers, and hydrocarbons. Its high volatility and low flash point make it extremely flammable, requiring careful handling and storage procedures.

What is furan used for?

Furan is primarily used as a chemical intermediate in the production of tetrahydrofuran (THF), which serves as an important industrial solvent. It is also utilized in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. Additionally, furan finds applications in the manufacture of certain polymers and resins, and as a building block for specialized organic compounds in research and development laboratories.

How to handle furan safely?

Furan must be handled with extreme caution due to its carcinogenic and highly flammable properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas or under fume hoods. Avoid all ignition sources, prevent vapor accumulation, and ensure emergency shower and eyewash stations are accessible. Only trained personnel should handle this substance following strict safety protocols.

How to store furan correctly?

Furan must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and direct sunlight. Use only approved containers made of compatible materials and ensure proper grounding to prevent static electricity buildup. Store separately from oxidizing agents, acids, and bases to prevent dangerous reactions. Maintain storage temperature below 15°C when possible and implement appropriate fire suppression systems in storage areas.

What to do in case of contact with furan?

Furan contact requires immediate action due to its toxic and irritating properties. For skin contact, immediately remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush thoroughly with water and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention, providing safety data sheet information to healthcare providers.

How to dispose of furan appropriately?

Furan disposal must comply with local and international hazardous waste regulations due to its carcinogenic classification. The substance should never be poured down drains or released into the environment. Contact licensed hazardous waste disposal companies for proper treatment, which typically involves high-temperature incineration under controlled conditions. Maintain detailed disposal records and ensure all containers are properly labeled before disposal to meet regulatory requirements.

How to transport furan?

Furan is classified as ADR Class 3 (flammable liquids), Packing Group I, indicating extremely high danger during transport. It must be shipped in UN-approved packaging with proper hazard labels and documentation. Vehicles must comply with ADR requirements including appropriate placarding, emergency equipment, and driver certification. Transport should avoid extreme temperatures and ensure proper segregation from incompatible materials during shipping.

Is furan subject to specific regulations?

Furan is subject to extensive regulatory oversight due to its carcinogenic classification (Carc. 1B) under CLP regulation. It falls under REACH registration requirements and various national chemical safety regulations. The substance requires specific labeling with GHS pictograms (GHS02, GHS07, GHS08) and 'Danger' signal word. Workplace exposure limits and specialized handling procedures are mandated in most jurisdictions, requiring compliance monitoring and reporting.

Where to buy furan in Europe?

Furan is available through specialized chemical distributors in Europe, including OYSI, which supplies high-quality chemical products across European markets. Due to its hazardous classification and regulatory requirements, purchases typically require proper documentation, safety certifications, and compliance with local regulations. Professional buyers should ensure suppliers provide comprehensive safety data sheets and maintain proper chain of custody documentation for regulatory compliance.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.