2-chlorobenzonitrile

2-chlorobenzonitrile is an aromatic organic compound with the molecular formula C7H4ClN and CAS number 873-32-5. It consists of a benzene ring substituted with both a chlorine atom and a nitrile group (-CN) at the ortho position. With a molecular weight of 137.56 g/mol, this compound is classified as a halogenated benzonitrile derivative commonly used as an intermediate in organic synthesis and pharmaceutical manufacturing.

2-chlorobenzonitrile is typically a white to pale yellow crystalline solid at room temperature with a characteristic aromatic odor. The compound exhibits limited water solubility due to its aromatic nature and chlorine substitution, but dissolves readily in organic solvents such as ethanol, acetone, and dichloromethane. Its nitrile group contributes to its polar character while the chlorine substitution affects its reactivity and physical properties.

2-chlorobenzonitrile serves primarily as an important intermediate in pharmaceutical synthesis and fine chemical manufacturing. It is commonly used in the production of various pharmaceutical compounds, agrochemicals, and specialty chemicals. The compound's reactive nitrile and chlorine functional groups make it valuable for further chemical transformations, including nucleophilic substitution reactions and nitrile group modifications in synthetic organic chemistry applications.

2-chlorobenzonitrile requires careful handling due to its classification as Acute Tox. 4 and Eye Irrit. 2. Always wear appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Avoid direct skin and eye contact, and prevent ingestion. Follow proper hygiene practices and wash hands thoroughly after handling.

2-chlorobenzonitrile should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly closed and store in original packaging or compatible chemical-resistant containers. Separate from incompatible materials such as strong oxidizing agents, strong bases, and reducing agents. Maintain storage temperatures below 25°C and protect from moisture to prevent degradation.

Immediate action is required in case of contact with 2-chlorobenzonitrile. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. If eye contact occurs, flush immediately with clean water for at least 15 minutes and seek medical attention. In case of inhalation, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention.

2-chlorobenzonitrile must be disposed of as hazardous chemical waste according to local, national, and EU regulations. Contact licensed waste disposal companies specialized in handling toxic chemicals. Never dispose of in regular waste streams, sewage systems, or environmental waters. Small quantities should be collected in appropriate containers and labeled properly. Follow your local authority's hazardous waste disposal procedures and maintain disposal records.

2-chlorobenzonitrile is classified under ADR Class 6.1 (Toxic substances), Packing Group III, indicating moderate toxicity during transport. It must be packaged in UN-approved containers with proper labeling including GHS07 pictogram and 'Warning' signal word. Transport vehicles must carry appropriate documentation and emergency response information. Only authorized carriers experienced with hazardous materials should handle transportation of this chemical.

2-chlorobenzonitrile is subject to REACH regulation requiring registration for manufacture or import above 1 ton annually in the EU. It falls under CLP classification as Acute Tox. 4 and Eye Irrit. 2, requiring appropriate labeling and safety data sheets. The substance is not listed as SVHC (Substance of Very High Concern), but users must comply with occupational exposure limits and workplace safety regulations.

2-chlorobenzonitrile is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides reliable supply of quality-controlled 2-chlorobenzonitrile to industrial and research customers across Europe. As an established chemical distributor, OYSI ensures proper handling, documentation, and regulatory compliance for all shipments. Contact OYSI directly for pricing, availability, and technical specifications tailored to your specific requirements.