7-methylquinolin-8-amine

7-methylquinolin-8-amine is an organic compound with the molecular formula C10H10N2 and CAS number 5470-82-6. This quinoline derivative features an amino group at position 8 and a methyl group at position 7 of the quinoline ring system. With a molecular weight of 158.2 g/mol, it belongs to the class of aminoquinolines and is classified as moderately hazardous with acute toxicity and skin sensitization properties.

7-methylquinolin-8-amine is a solid compound at room temperature with a molecular weight of 158.2 g/mol. As a quinoline derivative, it typically appears as a crystalline solid with characteristic aromatic properties. The compound contains both aromatic and amino functional groups, which influence its solubility and reactivity. Its physicochemical behavior is determined by the presence of the nitrogen-containing heterocyclic ring system and the amino substituent.

7-methylquinolin-8-amine serves as an important intermediate in pharmaceutical and chemical synthesis. This aminoquinoline compound is primarily used in the development of medicinal compounds, particularly those targeting antimalarial and antibacterial applications. It also functions as a building block in organic synthesis for creating more complex molecular structures. The compound's quinoline backbone makes it valuable for research in drug discovery and chemical manufacturing processes.

7-methylquinolin-8-amine requires careful handling due to its Acute Tox. 4 and Skin Sens. 1 classifications. Always wear appropriate personal protective equipment including gloves, safety glasses, and protective clothing to prevent skin contact. Work in well-ventilated areas or use local exhaust ventilation to minimize inhalation exposure. Avoid creating dust and prevent contact with eyes, skin, and clothing. Follow good industrial hygiene practices and wash hands thoroughly after handling.

7-methylquinolin-8-amine should be stored in tightly closed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep the material separated from incompatible substances and oxidizing agents. Store in accordance with local regulations for toxic substances, ensuring proper labeling with GHS pictograms GHS07 and GHS09. Maintain storage temperatures within recommended ranges and implement appropriate inventory management to ensure material integrity.

In case of skin contact with 7-methylquinolin-8-amine, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and seek medical advice if symptoms persist. In case of ingestion, do not induce vomiting and seek immediate medical attention.

7-methylquinolin-8-amine must be disposed of according to local, regional, and national environmental regulations as a hazardous waste. Do not dispose of this material in regular waste streams or pour down drains. Contact licensed waste disposal companies for proper treatment and disposal. The compound's Aquatic Chronic 2 classification requires special attention to prevent environmental contamination. Maintain proper documentation of waste disposal activities and follow all applicable waste management protocols.

7-methylquinolin-8-amine is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation during transport. Use approved containers and ensure proper marking with hazard labels. Transport vehicles must comply with ADR regulations for toxic substances. Drivers require appropriate training and certification. Emergency response information must accompany shipments, and transport must follow designated routes where applicable.

7-methylquinolin-8-amine is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The compound is classified with specific hazard classes requiring appropriate labeling with Warning signal word and GHS pictograms. It is not currently listed as an SVHC (Substance of Very High Concern). Users must comply with occupational safety regulations, environmental protection laws, and transportation requirements under ADR Class 6.1 provisions.

7-methylquinolin-8-amine is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides reliable supply chains for laboratory and industrial customers across Europe, ensuring compliance with REACH regulations and proper documentation. The company offers technical support and maintains appropriate storage and handling capabilities for this ADR Class 6.1 substance. Contact OYSI directly for availability, specifications, and delivery information tailored to your specific requirements.