7-methylquinolin-8-amine

7-methylquinolin-8-amine is an organic chemical compound with the molecular formula C10H10N2 and CAS number 5470-82-6. This aminoquinoline derivative has a molecular weight of 158.2 g/mol and features a quinoline ring system with an amino group at the 8-position and a methyl substituent at the 7-position. It is classified as a moderately hazardous substance with acute toxicity and skin sensitization properties.

7-methylquinolin-8-amine is a solid organic compound at room temperature with a molecular formula of C10H10N2. As an aminoquinoline derivative, it typically appears as a crystalline solid and exhibits basic properties due to the presence of amino nitrogen atoms. The compound has limited water solubility but dissolves well in organic solvents. Its aromatic quinoline structure contributes to its stability and chemical reactivity patterns.

7-methylquinolin-8-amine serves as an important intermediate in pharmaceutical synthesis and organic chemistry research. The compound is primarily used in the development of quinoline-based drugs and bioactive molecules. Its aminoquinoline structure makes it valuable for medicinal chemistry applications, particularly in the synthesis of antimalarial agents and other therapeutic compounds. It also finds applications in chemical research and development laboratories.

7-methylquinolin-8-amine requires careful handling due to its Acute Tox. 4 and Skin Sens. 1 classifications. Essential protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Work in well-ventilated areas or under fume hoods to avoid inhalation. The compound carries GHS07 and GHS09 pictograms with a Warning signal word, indicating moderate hazards requiring standard laboratory safety precautions.

7-methylquinolin-8-amine should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight. As a skin sensitizer and moderately toxic compound, it must be kept in designated chemical storage areas with appropriate labeling. Store away from incompatible materials and ensure containers are properly sealed to prevent moisture absorption. Maintain storage temperatures within recommended ranges to preserve compound stability.

7-methylquinolin-8-amine exposure requires immediate first aid due to its acute toxicity and skin sensitization properties. For skin contact, immediately remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with clean water for 15 minutes. Seek medical attention if symptoms develop or persist, and always consult safety data sheets for complete emergency procedures.

7-methylquinolin-8-amine disposal must comply with local and national hazardous waste regulations due to its toxic and environmentally hazardous properties. The compound cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment. Contact licensed waste disposal companies for proper collection and treatment. Small laboratory quantities may be suitable for chemical waste incineration at appropriate facilities following regulatory guidelines.

7-methylquinolin-8-amine is classified under ADR Class 6.1 (Toxic substances), Packing Group III, indicating moderate toxicity for transportation purposes. The compound requires appropriate hazardous goods packaging, labeling, and documentation for shipping. Transport containers must meet UN specifications for Class 6.1 materials and display proper hazard labels. Only qualified carriers with hazardous materials certification should handle the transportation of this chemical.

7-methylquinolin-8-amine is subject to standard European chemical regulations including REACH and CLP classifications. The compound is not currently listed as an SVHC (Substance of Very High Concern) under REACH. It must be handled according to its Acute Tox. 4 and Skin Sens. 1 classifications under CLP regulation. Users must comply with workplace safety regulations and maintain appropriate risk assessments and safety documentation.

7-methylquinolin-8-amine is available through OYSI, a European distributor specializing in technical chemicals and pharmaceutical intermediates. OYSI provides reliable supply chains across Europe with proper regulatory compliance and quality documentation. The company ensures appropriate packaging, labeling, and shipping procedures for hazardous chemicals like 7-methylquinolin-8-amine. Contact OYSI directly for availability, specifications, and regulatory documentation requirements for your specific application needs.