3-methylaniline
C7H9N
Consulting for 3-methylaniline
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Identification
- CAS Number
- 108-44-1
- EC Number
- 203-583-1
- UN Number
- 1708
- Index Number
- 612-024-00-4
- PubChem CID
- 7934
Physical-chemical properties
- Molecular Formula
- C7H9N
- Molar Mass
- 107.15 g/mol
- IUPAC Name
- 3-methylaniline
Chemical Identifiers
- InChI
- InChI=1S/C7H9N/c1-6-3-2-4-7(8)5-6/h2-5H,8H2,1H3
- InChI Key
- JJYPMNFTHPTTDI-UHFFFAOYSA-N
Overview
3-methylaniline (CAS 108-44-1) is an aromatic amine compound with significant industrial applications in chemical synthesis and manufacturing processes. This organic compound, also known by its IUPAC name 3-methylaniline, belongs to the family of substituted anilines featuring a methyl group attached to the benzene ring at the meta position relative to the amino group. With a molecular formula of C7H9N and molecular weight of 107.15 g/mol, 3-methylaniline appears as a colorless to pale yellow liquid that darkens upon exposure to air and light. The compound is characterized by its distinctive amine odor and demonstrates typical properties of aromatic amines. Safety considerations are paramount when handling 3-methylaniline, as it carries significant health hazards. The substance is classified under multiple acute toxicity categories and poses risks for specific target organ toxicity following repeated exposure. Additionally, it presents environmental concerns due to its aquatic acute toxicity classification. The GHS pictograms GHS06, GHS08, and GHS09 indicate toxic, health hazard, and environmental hazard properties respectively, requiring careful handling protocols and appropriate personal protective equipment. In industrial applications, 3-methylaniline serves as a crucial intermediate in the production of dyes and pigments, particularly in the synthesis of azo dyes and other colorants. The chemical industry also utilizes this compound in the manufacture of pharmaceuticals and agrochemicals, where its aromatic amine structure provides essential building blocks for more complex molecules. Like other aromatic amines such as N-methylaniline, 3-methylaniline plays a vital role in organic synthesis reactions. OYSI maintains reliable supply chains for 3-methylaniline to support European industrial customers requiring this essential chemical intermediate.
Safety & Classification
Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE 2 *; Aquatic Acute 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1708 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | m-Toluidin, flüssig |
| Marine Pollutant | No |
Frequently Asked Questions
What is 3-methylaniline?
3-methylaniline is an aromatic amine compound with the molecular formula C7H9N and CAS number 108-44-1. It consists of an aniline molecule with a methyl group attached to the third position of the benzene ring. With a molecular weight of 107.15 g/mol, this organic compound is classified as a toxic substance requiring careful handling due to its acute toxicity and potential health hazards.
What are the physicochemical properties of 3-methylaniline?
3-methylaniline is typically a colorless to pale yellow liquid at room temperature with a characteristic amine odor. It has moderate solubility in water and is miscible with most organic solvents including alcohols and ethers. The compound has a boiling point around 203°C and exhibits basic properties due to the amino group, making it reactive with acids to form salts.
What is 3-methylaniline used for?
3-methylaniline is primarily used as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It serves as a building block for manufacturing various azo dyes and organic colorants used in textile and printing industries. Additionally, it finds applications in the production of agricultural chemicals, rubber additives, and as a chemical intermediate in organic synthesis processes.
How to handle 3-methylaniline safely?
3-methylaniline requires strict safety measures due to its acute toxicity classification. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Avoid skin contact and inhalation as the compound can be absorbed through skin and cause systemic toxicity. Work in fume hoods and ensure emergency shower facilities are readily available.
How to store 3-methylaniline correctly?
3-methylaniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep away from strong oxidizing agents, acids, and incompatible materials. Storage areas must be equipped with appropriate spill containment measures and maintained at controlled temperatures. Ensure containers are properly labeled and stored in secondary containment systems.
What to do in case of contact with 3-methylaniline?
Immediate action is required upon contact with 3-methylaniline. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with water for 15 minutes. Seek immediate medical attention in all cases, as the compound can cause systemic toxicity and requires professional medical evaluation.
How to dispose of 3-methylaniline appropriately?
3-methylaniline must be disposed of as hazardous waste according to local and European regulations. The compound cannot be discharged to sewers or environment due to its aquatic toxicity classification. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities should be collected in appropriate containers and labeled for hazardous waste pickup. Follow all applicable waste codes and documentation requirements.
How to transport 3-methylaniline?
3-methylaniline is classified under ADR as Class 6.1 (toxic substances), Packing Group II, requiring specific transport regulations. It must be packaged in UN-approved containers with proper labeling including GHS06, GHS08, and GHS09 pictograms. Transport vehicles must carry appropriate emergency equipment and documentation. Only certified carriers experienced in handling toxic chemicals should transport this substance.
Is 3-methylaniline subject to specific regulations?
3-methylaniline is subject to various European regulations including REACH registration requirements and CLP classification. It carries the signal word 'Danger' and multiple hazard classifications including acute toxicity and aquatic environmental hazards. While not currently listed as an SVHC substance, it requires compliance with occupational exposure limits, environmental discharge restrictions, and proper hazard communication throughout the supply chain.
Where to buy 3-methylaniline in Europe?
3-methylaniline is available through OYSI, a specialized European distributor of technical chemicals. As an established supplier in the European market, OYSI provides quality chemical products with proper documentation and regulatory compliance. Contact OYSI directly for availability, specifications, and technical support. Ensure any supplier provides complete safety documentation and meets all regulatory requirements for this controlled substance.
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3-methylaniline is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.