3-methylaniline
C7H9N
Consulting for 3-methylaniline
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Identification
- CAS Number
- 108-44-1
- EC Number
- 203-583-1
- UN Number
- 1708
- Index Number
- 612-024-00-4
- PubChem CID
- 7934
Physical-chemical properties
- Molecular Formula
- C7H9N
- Molar Mass
- 107.15 g/mol
- IUPAC Name
- 3-methylaniline
Chemical Identifiers
- InChI
- InChI=1S/C7H9N/c1-6-3-2-4-7(8)5-6/h2-5H,8H2,1H3
- InChI Key
- JJYPMNFTHPTTDI-UHFFFAOYSA-N
Overview
3-methylaniline (CAS 108-44-1) is an aromatic amine compound with a methyl group substituted at the meta position of the aniline ring. This organic chemical intermediate plays a crucial role in various industrial manufacturing processes, particularly in the production of dyes, pharmaceuticals, and specialty chemicals. With its molecular formula C7H9N and molar mass of 107.15 g/mol, 3-methylaniline exhibits the characteristic properties of aromatic amines while offering unique reactivity due to its specific substitution pattern. The compound appears as a colorless to pale yellow liquid with a characteristic amine odor. Safety considerations are paramount when handling 3-methylaniline, as it carries significant hazard classifications including acute toxicity through multiple exposure routes and specific target organ toxicity. The substance requires careful handling protocols due to its GHS06, GHS08, and GHS09 pictograms, indicating acute toxicity, health hazards, and environmental dangers respectively. Its ADR classification as Class 6.1 further emphasizes the need for appropriate transportation and storage measures. Like other aromatic amines in its chemical family, including N-methylaniline, 3-methylaniline can pose risks to both human health and aquatic environments. Industrial applications of 3-methylaniline include its use as an intermediate in pharmaceutical synthesis, particularly for medications requiring meta-substituted aniline building blocks. The compound also serves as a precursor in dye manufacturing, where its specific substitution pattern provides unique color properties. Additionally, it functions as a chemical intermediate in the production of agrochemicals and specialty polymers. OYSI maintains reliable supply chains for 3-methylaniline to support European industrial customers requiring this essential chemical intermediate for their manufacturing operations.
Safety & Classification
Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT RE 2 *; Aquatic Acute 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1708 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | m-Toluidin, flüssig |
| Marine Pollutant | No |
Frequently Asked Questions
What is 3-methylaniline?
3-methylaniline is an aromatic amine compound with the molecular formula C7H9N and CAS number 108-44-1. It consists of an aniline molecule with a methyl group attached to the third carbon position of the benzene ring. This organic compound has a molecular weight of 107.15 g/mol and belongs to the class of substituted anilines, which are important intermediates in chemical synthesis and industrial applications.
What are the physicochemical properties of 3-methylaniline?
3-methylaniline is typically a liquid at room temperature with a characteristic aromatic amine odor. As an aromatic amine, it exhibits moderate solubility in water and good solubility in organic solvents such as ethanol, ether, and benzene. The compound tends to darken upon exposure to air and light due to oxidation. Its boiling point is around 203°C, and it has a density slightly higher than water.
What is 3-methylaniline used for?
3-methylaniline serves as an important intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It is commonly used in the production of azo dyes, particularly those requiring meta-substituted aniline derivatives. The compound also finds applications in the manufacture of pesticides, rubber chemicals, and various organic synthesis processes where aromatic amines are required as building blocks for more complex molecular structures.
How to handle 3-methylaniline safely?
3-methylaniline requires careful handling due to its Acute Tox. 3 classification and potential for organ damage. Always wear appropriate personal protective equipment including nitrile gloves, safety goggles, and respiratory protection when handling. Work in well-ventilated areas or under fume hoods to avoid inhalation. Prevent skin and eye contact, as the substance can be absorbed through skin and cause systemic toxicity.
How to store 3-methylaniline correctly?
3-methylaniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources, oxidizing agents, and strong acids. Keep containers away from direct sunlight to prevent degradation and discoloration. Store separately from incompatible materials and ensure proper labeling with hazard information. Maintain storage temperatures below 25°C and check containers regularly for signs of deterioration or leakage.
What to do in case of contact with 3-methylaniline?
Immediate action is required upon contact with 3-methylaniline due to its toxicity. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with plenty of clean water for 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly for any exposure, especially if symptoms develop.
How to dispose of 3-methylaniline properly?
3-methylaniline must be disposed of as hazardous waste according to local and EU regulations due to its toxicity and environmental hazard classification. Contact licensed waste disposal companies specializing in chemical waste treatment. Never dispose of in regular waste streams, sewers, or water bodies. Small quantities should be collected in appropriate containers and labeled for professional disposal. Follow all applicable waste codes and documentation requirements.
How to transport 3-methylaniline?
3-methylaniline is classified as ADR Class 6.1 (toxic substances), Packing Group II, requiring specific transport regulations. It must be packaged in UN-approved containers with proper hazard labels and documentation. Transport vehicles need appropriate placarding and drivers require ADR certification. The substance requires careful handling during loading and unloading, with emergency response information readily available throughout transport.
Is 3-methylaniline subject to specific regulations?
3-methylaniline is subject to various European regulations including REACH registration requirements and CLP classification as a hazardous substance. While not currently listed as an SVHC (Substance of Very High Concern), it requires safety data sheets and proper hazard communication. Users must comply with occupational exposure limits, environmental discharge restrictions, and industrial emissions regulations where applicable.
Where to buy 3-methylaniline in Europe?
3-methylaniline is available through OYSI, a specialized European distributor of chemical products. As an established chemical supplier, OYSI can provide 3-methylaniline with proper documentation, safety data sheets, and regulatory compliance for European markets. Contact OYSI directly for availability, specifications, and technical support to ensure you receive the appropriate grade and packaging for your specific industrial or research applications.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.