2-aminophenol

2-aminophenol is an organic compound with the molecular formula C6H7NO and CAS number 95-55-6. It belongs to the aminophenol family, featuring both amino (-NH2) and hydroxyl (-OH) functional groups attached to a benzene ring. With a molecular weight of 109.13 g/mol, this chemical is classified as hazardous with mutagenic properties (Muta. 2) and acute toxicity (Acute Tox. 4). It requires careful handling due to its potential health risks and is widely used in various industrial applications.

2-aminophenol appears as crystalline solid or powder, typically light brown to reddish-brown in color. It has a molecular weight of 109.13 g/mol and is moderately soluble in water, with higher solubility in alcohols and organic solvents. The compound is sensitive to light and air, which can cause oxidation and color changes. It exhibits both acidic and basic properties due to its phenolic hydroxyl group and amino group, making it amphoteric in nature.

2-aminophenol serves primarily as an intermediate in the production of hair dyes, pharmaceuticals, and various organic compounds. It is extensively used in the cosmetic industry for manufacturing permanent and semi-permanent hair colorants. Additionally, it finds applications in pharmaceutical synthesis, particularly in producing certain analgesics and antipyretics. The compound is also utilized in the production of photographic chemicals, rubber antioxidants, and as a chemical intermediate for synthesizing other aminophenol derivatives.

2-aminophenol requires strict safety measures due to its mutagenic and toxic properties. Always wear appropriate personal protective equipment including nitrile gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact completely. Use non-sparking tools and equipment. Implement proper hygiene measures including washing hands thoroughly after handling. Never eat, drink, or smoke while working with this substance. Store and handle according to local safety regulations.

2-aminophenol must be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep containers in secondary containment to prevent spills. Store separately from strong oxidizing agents, acids, and incompatible materials. Maintain storage temperatures below 25°C to prevent degradation. Use original labeled containers and ensure proper inventory management. Implement appropriate fire prevention measures and restrict access to authorized personnel only. Regular inspection of storage conditions is essential.

Immediate action is required upon contact with 2-aminophenol. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any exposure and provide the safety data sheet to medical personnel.

2-aminophenol disposal must comply with local and international waste regulations due to its hazardous classification. Never dispose of this substance in regular waste streams or pour down drains. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may require incineration at authorized facilities with appropriate emission controls. Document all disposal activities according to regulatory requirements. Consider waste minimization strategies and recovery options where applicable. Always consult local environmental authorities for specific disposal guidelines.

2-aminophenol is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. It requires proper packaging in UN-approved containers with appropriate hazard labels and documentation. Transport vehicles must display proper placarding and carry emergency response information. Drivers need hazardous materials training and certification. Shipping papers must include proper shipping names, hazard classes, and emergency contact information. Ensure compliance with international transport regulations (ADR/RID for road/rail, IMDG for sea, IATA for air transport).

2-aminophenol is subject to multiple regulatory frameworks including REACH registration requirements in Europe and CLP classification for hazard communication. Its mutagenic classification (Muta. 2) triggers specific handling and exposure limit requirements under occupational safety regulations. The substance is not currently listed as SVHC under REACH but may be subject to cosmetic regulations when used in hair dye formulations. Companies must maintain safety data sheets, implement risk assessments, and comply with notification requirements for industrial use.

2-aminophenol is available through OYSI, a trusted European distributor of specialty chemicals serving various industries across the continent. OYSI provides high-quality 2-aminophenol with proper documentation, safety data sheets, and regulatory compliance support. As an established chemical distributor, OYSI ensures reliable supply chains, appropriate packaging, and technical support for industrial customers. Contact OYSI directly for availability, specifications, and pricing information tailored to your specific application requirements and volume needs.