2-aminophenol

2-aminophenol is an organic compound with the molecular formula C6H7NO and CAS number 95-55-6. It belongs to the aminophenol family, featuring both amino (-NH2) and hydroxyl (-OH) groups attached to a benzene ring. With a molecular weight of 109.13 g/mol, this chemical is classified as a mutagenic substance (Category 2) and acutely toxic (Category 4), requiring careful handling in industrial applications.

2-aminophenol typically appears as crystalline solid ranging from white to light brown in color. It exhibits moderate water solubility and is soluble in alcohols and other organic solvents. The compound has a characteristic phenolic odor and tends to darken upon exposure to air and light due to oxidation. Its melting point and other thermal properties make it suitable for various chemical synthesis processes.

2-aminophenol serves primarily as an intermediate in pharmaceutical synthesis and dye manufacturing. It is commonly used in the production of hair dyes, photographic developers, and various organic compounds. The chemical also finds application in the synthesis of benzoxazoles and other heterocyclic compounds. Additionally, it serves as a precursor for certain pharmaceutical compounds and analytical reagents in laboratory settings.

2-aminophenol requires careful handling due to its mutagenic and acute toxicity properties. Workers must wear appropriate personal protective equipment including nitrile gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. The substance carries GHS08 and GHS07 pictograms with a 'Warning' signal word, indicating moderate hazard levels.

2-aminophenol should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. The storage area must be protected from moisture and incompatible materials such as strong oxidizing agents. Containers should be made of compatible materials and properly labeled according to CLP regulations. Regular inspection for container integrity and proper segregation from incompatible chemicals is essential.

2-aminophenol exposure requires immediate action. For skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move the person to fresh air and seek medical attention. For ingestion, do not induce vomiting and seek immediate medical care.

2-aminophenol disposal must comply with local and European waste regulations due to its hazardous classification. The substance cannot be disposed of in regular waste streams and requires treatment by authorized hazardous waste disposal companies. Small laboratory quantities may be collected in appropriate waste containers for chemical disposal. Incineration at high temperatures in specialized facilities is typically the preferred disposal method for this compound.

2-aminophenol is classified under ADR Class 6.1 (toxic substances) Packing Group III, indicating moderate danger during transport. It must be packaged in UN-approved containers with proper labeling and documentation. Transport vehicles require appropriate placarding and trained drivers with ADR certification. The substance must be segregated from incompatible materials and protected from damage during transit according to dangerous goods transportation regulations.

2-aminophenol is regulated under various European frameworks including REACH and CLP regulations due to its hazardous properties. While not currently listed as a SVHC (Substance of Very High Concern), its mutagenic classification (Muta. 2) subjects it to strict handling and reporting requirements. Companies using this substance must comply with worker safety regulations, environmental protection measures, and appropriate risk assessment procedures under occupational health legislation.

2-aminophenol is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI provides this compound to industrial customers across Europe with proper documentation and regulatory compliance. The company ensures appropriate packaging, labeling, and transportation according to ADR requirements. Contact OYSI directly for availability, technical specifications, and delivery options to your specific European location.