4-aminophenol

4-aminophenol is an organic compound with the molecular formula C6H7NO and CAS number 123-30-8. It is an aromatic amine derivative of phenol, featuring both amino and hydroxyl functional groups on a benzene ring. With a molecular weight of 109.13 g/mol, this chemical substance is classified as mutagenic category 2 and acutely toxic category 4, requiring careful handling in industrial applications.

4-aminophenol is typically a white to light brown crystalline solid at room temperature. It has moderate water solubility and can dissolve in polar organic solvents. The compound may darken upon exposure to air and light due to oxidation. Its molecular structure contains both hydrophilic (amino and hydroxyl groups) and hydrophobic (benzene ring) components, influencing its solubility characteristics and chemical reactivity.

4-aminophenol serves as an important intermediate in pharmaceutical manufacturing, particularly in the synthesis of paracetamol (acetaminophen). It is also used in the production of dyes, photographic developers, and other organic compounds. The chemical industry utilizes it as a building block for various aromatic compounds and specialty chemicals. Its dual functional groups make it valuable for chemical modifications and coupling reactions.

4-aminophenol requires careful handling due to its mutagenic and acute toxicity properties. Wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation and avoid inhalation of dust or vapors. Handle in a controlled environment, preferably under a fume hood. Avoid skin and eye contact, and prevent ingestion. Follow proper hygiene practices and wash hands thoroughly after handling.

4-aminophenol should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and oxidation. Store away from incompatible materials such as strong oxidizing agents, acids, and bases. Maintain storage temperatures below 25°C when possible. Ensure proper labeling and access control due to its hazardous classification. Use appropriate secondary containment measures.

In case of skin contact with 4-aminophenol, immediately remove contaminated clothing and wash the affected area with plenty of water for at least 15 minutes. For eye contact, rinse immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a healthcare professional after any significant exposure.

4-aminophenol waste must be disposed of through authorized hazardous waste management companies due to its toxic and mutagenic properties. Never dispose of it in regular waste streams or pour down drains. The substance requires special treatment due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1). Contact certified waste disposal contractors and follow local environmental regulations. Maintain proper waste documentation and manifests as required by law.

4-aminophenol is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation. It requires appropriate hazardous goods packaging, labeling, and documentation during transport. Shipping containers must meet UN specifications and display proper hazard labels including GHS pictograms (GHS07, GHS08, GHS09). Transport vehicles must comply with ADR regulations, and drivers need appropriate hazardous materials training. Proper shipping papers and emergency response information are mandatory.

4-aminophenol is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification obligations. It is classified as Muta. 2, Acute Tox. 4, and carries aquatic hazard classifications, requiring appropriate risk management measures. While not currently listed as an SVHC substance, it requires safety data sheets and proper hazard communication. Manufacturers and importers must comply with registration, evaluation, and authorization requirements under applicable chemical legislation.

4-aminophenol is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI provides quality 4-aminophenol with proper documentation, safety data sheets, and regulatory compliance support. They serve industrial customers across Europe with technical-grade chemicals for pharmaceutical, chemical manufacturing, and research applications. Contact OYSI directly for availability, specifications, and technical support for your 4-aminophenol requirements.