1,2-dimethoxyethane

C4H10O2

CAS110-71-4
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
110-71-4
EC Number
203-794-9
UN Number
2252
Index Number
603-031-00-3
PubChem CID
8071

Physical-chemical properties

Molecular Formula
C4H10O2
Molar Mass
90.12 g/mol
IUPAC Name
1,2-dimethoxyethane

Chemical Identifiers

InChI
InChI=1S/C4H10O2/c1-5-3-4-6-2/h3-4H2,1-2H3
InChI Key
XTHFKEDIFFGKHM-UHFFFAOYSA-N

Overview

1,2-Dimethoxyethane (CAS 110-71-4) is a glycol ether solvent with excellent solvating properties and chemical stability under controlled conditions. 1,2-Dimethoxyethane, also known by its CAS number 110-71-4, represents an important member of the glycol ether family widely utilized in industrial chemical processes. With the molecular formula C4H10O2 and a molecular weight of 90.12 g/mol, this colorless liquid exhibits exceptional solvent characteristics that make it valuable across multiple industrial sectors. The compound's structure features two methoxy groups attached to an ethane backbone, providing unique chemical properties that distinguish it from other organic solvents. The substance demonstrates excellent miscibility with water and most organic solvents, offering superior performance in applications requiring strong solvating power. Its ability to dissolve a wide range of polar and non-polar compounds makes it particularly valuable in specialized chemical processes. However, 1,2-dimethoxyethane requires careful handling due to its classification as a flammable liquid (Category 2) and reproductive toxicant (Category 1B), indicated by the danger signal word and corresponding GHS pictograms GHS02, GHS08, and GHS07. Primary industrial applications include its use as a reaction medium in organometallic chemistry, where its coordinating properties stabilize metal complexes, and as a solvent in polymer synthesis processes. The compound also serves as an electrolyte component in lithium battery systems, where its chemical stability proves advantageous compared to other glycol ethers. While chemically distinct from aromatic solvents like ethylbenzene, 1,2-dimethoxyethane often provides alternative solvating solutions in applications where aromatic compounds are unsuitable. OYSI maintains reliable supplies of 1,2-dimethoxyethane to support diverse European industrial requirements, ensuring consistent quality and regulatory compliance for technical applications.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Repr. 1B; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H332

Harmful if inhaled.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2252
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name1,2-Dimethoxyethan
Marine PollutantNo

Frequently Asked Questions

What is 1,2-dimethoxyethane?

1,2-dimethoxyethane is an organic solvent with the molecular formula C4H10O2 and CAS number 110-71-4. This ether compound has a molecular weight of 90.12 g/mol and belongs to the glycol ether family. It is classified as a flammable liquid with reproductive toxicity and acute toxicity properties. The substance is widely used in industrial applications due to its excellent solvating properties and ability to form complexes with metal ions.

What are the physicochemical properties of 1,2-dimethoxyethane?

1,2-dimethoxyethane is a colorless liquid at room temperature with a characteristic ether-like odor. It has excellent solubility in water and most organic solvents due to its ether structure. The compound is highly volatile and has a relatively low boiling point. Its chemical structure consists of an ethylene glycol backbone with both hydroxyl groups replaced by methoxy groups, giving it unique chelating properties that make it valuable as a coordinating solvent.

What is 1,2-dimethoxyethane used for?

1,2-dimethoxyethane is primarily used as a polar aprotic solvent in organic synthesis and electrochemistry. It serves as an excellent medium for organometallic reactions, particularly those involving lithium and magnesium compounds. The substance is also employed in battery electrolytes, polymer synthesis, and as a chelating agent in coordination chemistry. Its ability to dissolve both organic and inorganic compounds makes it valuable in pharmaceutical manufacturing and advanced chemical processes.

How to handle 1,2-dimethoxyethane safely?

1,2-dimethoxyethane requires careful handling due to its flammable and toxic properties. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Keep away from ignition sources, heat, and open flames. Use grounded equipment to prevent static discharge. Avoid skin and eye contact, and never eat, drink, or smoke when handling this substance.

How to store 1,2-dimethoxyethane correctly?

1,2-dimethoxyethane must be stored in a cool, dry, well-ventilated area away from heat sources and ignition points. Keep containers tightly closed and store in original packaging or compatible containers. The substance should be segregated from strong oxidizing agents, acids, and bases. Store below 25°C and protect from direct sunlight. Ensure proper grounding of storage containers and maintain appropriate fire suppression systems in storage areas due to its flammable nature.

What to do in case of contact with 1,2-dimethoxyethane?

In case of skin contact with 1,2-dimethoxyethane, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes and seek medical attention. If inhaled, move the person to fresh air and keep them at rest. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any significant exposure.

How to dispose of 1,2-dimethoxyethane appropriately?

1,2-dimethoxyethane must be disposed of as hazardous waste in accordance with local, national, and EU regulations. Never pour down drains or dispose of with regular waste. The substance requires specialized treatment at authorized waste disposal facilities. Container residues should also be treated as hazardous waste. Consult your local waste management authority for specific disposal requirements and approved disposal facilities. Keep proper documentation of waste disposal for regulatory compliance.

How to transport 1,2-dimethoxyethane?

1,2-dimethoxyethane is classified under ADR Class 3 (flammable liquids), Packing Group II, indicating moderate danger level. Transportation requires proper packaging in UN-approved containers with appropriate labeling including GHS02, GHS07, and GHS08 pictograms. Vehicles must carry appropriate safety equipment and drivers need ADR certification. The substance requires proper documentation including transport documents and emergency response information. Ensure compliance with all applicable transportation regulations for dangerous goods.

Is 1,2-dimethoxyethane subject to specific regulations?

1,2-dimethoxyethane is subject to comprehensive EU chemical regulations including REACH and CLP classification. The substance is classified as Flam. Liq. 2, Repr. 1B, and Acute Tox. 4, requiring specific labeling with danger signal word and appropriate pictograms. While not currently listed as SVHC, its reproductive toxicity classification means it may face restrictions in consumer applications. Companies must comply with registration, notification, and safety data sheet requirements under REACH and CLP regulations.

Where to buy 1,2-dimethoxyethane in Europe?

1,2-dimethoxyethane is available through OYSI, a trusted European distributor of technical chemicals. OYSI provides high-quality chemical products with proper documentation and regulatory compliance for industrial and research applications. As a specialized chemical distributor, OYSI ensures appropriate packaging, labeling, and safety data sheets meeting EU requirements. Contact OYSI directly for availability, specifications, and ordering information for 1,2-dimethoxyethane and other specialty chemicals across European markets.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.