4-methylpentan-2-one

C6H12O

CAS108-10-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
108-10-1
EC Number
203-550-1
UN Number
1245
Index Number
606-004-00-4
PubChem CID
7909

Physical-chemical properties

Molecular Formula
C6H12O
Molar Mass
100.16 g/mol
IUPAC Name
4-methylpentan-2-one

Chemical Identifiers

InChI
InChI=1S/C6H12O/c1-5(2)4-6(3)7/h5H,4H2,1-3H3
InChI Key
NTIZESTWPVYFNL-UHFFFAOYSA-N

Overview

4-methylpentan-2-one (CAS 108-10-1) is an organic ketone solvent with excellent dissolving properties and moderate volatility for industrial applications. This branched-chain ketone, also known by its IUPAC designation 4-methylpentan-2-one, represents a versatile organic compound widely utilized across multiple industrial sectors. With the molecular formula C6H12O and a molecular weight of 100.16 g/mol, this colorless liquid solvent exhibits characteristic ketone properties that make it particularly valuable for specialized chemical processes and formulations. The compound's chemical structure features a ketone functional group positioned at the second carbon of a methylated pentane chain, contributing to its distinctive solvent characteristics. This structural arrangement provides balanced polarity and volatility properties, distinguishing it from other industrial solvents like ethylbenzene, which offers different solubility profiles for aromatic compounds. Safety considerations are paramount when handling 4-methylpentan-2-one, as it carries multiple hazard classifications including flammable liquid category 2, suspected carcinogen category 2, and acute toxicity category 4. The substance requires careful storage and handling protocols, with appropriate ventilation and personal protective equipment mandatory during use. Its ADR class 3 classification necessitates compliance with specific transportation regulations for flammable liquids. Primary industrial applications include its use as a specialized solvent in coating formulations, chemical synthesis intermediates, and extraction processes. The compound also serves in pharmaceutical manufacturing and specialty chemical production where its unique solvent properties are essential. OYSI maintains reliable European supply chains for 4-methylpentan-2-one, ensuring consistent availability for technical and industrial customers requiring this specialized ketone solvent.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Carc. 2; Acute Tox. 4; STOT SE 3; Eye Irrit. 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H351

Suspected of causing cancer.

H332

Harmful if inhaled.

H336

May cause drowsiness or dizziness.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1245
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameMethylisobutylketon
Marine PollutantNo

Frequently Asked Questions

What is 4-methylpentan-2-one?

4-methylpentan-2-one is an organic ketone with the molecular formula C6H12O and CAS number 108-10-1. This chemical compound has a molecular weight of 100.16 g/mol and belongs to the family of methyl ketones. It is classified as a flammable liquid with carcinogenic properties and represents significant health hazards requiring careful handling in industrial applications.

What are the physicochemical properties of 4-methylpentan-2-one?

4-methylpentan-2-one is a colorless liquid ketone with a characteristic sweet, fruity odor typical of ketones. It has moderate volatility at room temperature and is partially soluble in water while being fully miscible with most organic solvents like alcohols and ethers. The compound exhibits typical ketone reactivity and maintains stability under normal storage conditions.

What is 4-methylpentan-2-one used for?

4-methylpentan-2-one serves primarily as a solvent in industrial applications and as an intermediate in organic synthesis. It is commonly used in the production of pharmaceuticals, agrochemicals, and specialty chemicals. The compound also finds applications in the formulation of coatings, adhesives, and cleaning products where its ketone properties provide effective solvency for various organic materials.

How to handle 4-methylpentan-2-one safely?

4-methylpentan-2-one requires strict safety protocols due to its flammable and carcinogenic nature. Workers must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Handle only in well-ventilated areas or under fume extraction, avoid all ignition sources, and ensure emergency shower and eyewash stations are readily accessible.

How to store 4-methylpentan-2-one correctly?

4-methylpentan-2-one must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use only approved containers resistant to ketones and ensure proper grounding to prevent static electricity buildup. Store separately from oxidizing agents, strong acids, and bases to prevent incompatible reactions that could lead to fire or explosion.

What to do in case of contact with 4-methylpentan-2-one?

4-methylpentan-2-one exposure requires immediate action depending on contact type. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with clean water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention.

How to dispose of 4-methylpentan-2-one appropriately?

4-methylpentan-2-one disposal must comply with local and European waste regulations as it is classified as hazardous waste. The compound should be collected in appropriate containers and disposed of through licensed hazardous waste disposal facilities. Incineration at high temperatures in specialized facilities is typically the preferred disposal method. Never discharge into sewers or the environment.

How to transport 4-methylpentan-2-one?

4-methylpentan-2-one is classified under ADR as Class 3 (Flammable Liquids), Packing Group II, indicating moderate danger during transport. It must be shipped in UN-approved packaging with proper hazard labels and documentation. Vehicles must be equipped with appropriate fire extinguishers and drivers must have ADR training certificates for transporting flammable liquids.

Is 4-methylpentan-2-one subject to specific regulations?

4-methylpentan-2-one is regulated under European REACH and CLP regulations due to its carcinogenic classification (Carc. 2). While not currently listed as an SVHC substance, its Category 2 carcinogen status requires specific risk management measures and safety data sheet provisions. Users must comply with occupational exposure limits and implement appropriate risk management strategies.

Where to buy 4-methylpentan-2-one in Europe?

4-methylpentan-2-one is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with complete regulatory documentation, safety data sheets, and technical support to ensure compliance with European regulations. As an established chemical distributor, OYSI ensures reliable supply chains and quality assurance for industrial customers across Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.